DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCAP-R and ops-1

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_500956.1	Gene:	ops-1 / 188465	WormBaseID:	WBGene00005744	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	391	Identity:	69/391 - (17%)
Similarity:	144/391 - (36%)	Gaps:	124/391 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 LFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTD------IIWRITISWRA 191
            |:.|:.:   .:|.:.:::|...|.....:.|..:|||...|:..:|:      :|.....::::
Worm    29 LYLVVFV---CLLRLRYVSKTYNSTFYSILLQHCIADLLAMLIFFVTNPMRTIPLIREFFFNYQS 90

  Fly   192 GNLACKAIRFSQVCVTYSSTYV--------LVAMSIDRYDAITHPM-NFSKSWKRARHL--VAGA 245
                     |.....:|:|.|.        ::.:|:.||..|..|| .|:...:.|..|  |...
Worm    91 ---------FYIAAASYNSIYYFLYIRCTGIIFLSLQRYFVICCPMLQFTYKIQNASKLTIVVIY 146

  Fly   246 WLISALFSLPIL--------------VLYEEKLIQGHPQCWIELGSPIAWQVYMSLVSATLFAIP 296
            |::..:.|..:|              ::.::.:||.:                 :|::..:..:.
Worm   147 WIVPTVISAVVLKDTDFSYDSFERMAIIADQDVIQRN-----------------TLMALVVVGLT 194

  Fly   297 ALIISACYAIIVKTIWAKGSIF--VPTERAGFGAAPARRASSRGIIPRAKVKTVKMTLTI-VFVF 358
            .::.|..|          |::|  :....||...:..|                ::.|.. |||.
Worm   195 CILCSLAY----------GALFYYIRKHTAGLSRSLRR----------------ELHLAFQVFVL 233

  Fly   359 IICWSPYIIFDLLQVFGQIPHSQT-NIAIATFIQSLAP----LNSAANPLIYCL------FSSQV 412
            ::.:...:::...|.:    .||| |.....::::|.|    |.|..||  :|:      .:.||
Worm   234 LLAFFAILVYYAFQNY----FSQTHNTGPIFYMRALYPVANGLLSYINP--FCILFLNRDLARQV 292

  Fly   413 FRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVV 477
            .:|:.           |..|:.:..|     |...:..|  :.|.....:.:.|||:.:...:|:
Worm   293 IKTIK-----------CSKYQVSDAQ-----VSGNVTTS--TKRASKKGIDLLRRSSEEPTPQVL 339

  Fly   478 I 478
            |
Worm   340 I 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	57/327 (17%)
		TM helix 1	126..150	CDD:320325	3/16 (19%)
		TM helix 2	159..182	CDD:320325	6/28 (21%)
		TM helix 3	197..219	CDD:320325	4/29 (14%)
		TM helix 4	240..256	CDD:320325	4/17 (24%)
		TM helix 5	282..305	CDD:320325	2/22 (9%)
		TM helix 6	348..370	CDD:320325	4/22 (18%)
		TM helix 7	384..409	CDD:320325	7/34 (21%)
ops-1	NP_500956.1	7TM_GPCR_Srv	19..298	CDD:370977	58/340 (17%)
		TM helix 2	51..74	CDD:341315	6/22 (27%)
		TM helix 3	86..124	CDD:341315	7/46 (15%)
		TM helix 4	137..157	CDD:341315	5/19 (26%)
		TM helix 5	179..204	CDD:341315	5/51 (10%)
		TM helix 6	221..247	CDD:341315	5/41 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24224
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100