DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCAP-R and C04C3.6

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_500342.1	Gene:	C04C3.6 / 182197	WormBaseID:	WBGene00015416	Length:	344	Species:	Caenorhabditis elegans

Alignment Length:	381	Identity:	76/381 - (19%)
Similarity:	140/381 - (36%)	Gaps:	100/381 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 STSSDPGEFDNLNSFYFYETEQFAVLW------ILFTVI---VLGNSAVLFVMFI--NKNRKSRM 158
            |:||:|.:.|       .|.:.|...|      :.:|||   |:...|::| |||  .|.:||..
Worm     3 SSSSEPRDLD-------AERDAFIKEWTATSQLLYYTVICVSVVTLPALIF-MFIVLRKYKKSNY 59

  Fly   159 NYFIKQLALAD---LCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYV---LVAM 217
            .:|:..:...:   |.....||::|....|......|.:.||   .|...|..||.:|   .|||
Worm    60 YHFLCAIMAGNFVLLATIFSNVISDRNVMIFAGIIPGVVVCK---LSAFLVNTSSFFVHWAWVAM 121

  Fly   218 SIDRYDAITHPMNFSKSWKRARHLVAGAWLISALFSL--PILV--------------LYEEKLIQ 266
            .:.|:..:..|:...::..:::.::...:..|.:..|  |||:              ..|:..|.
Worm   122 YVQRFLHVFFPLRSHRAGDKSKEIIGVLFAFSVISQLWTPILITELSVGADASSGTYCAEDPRIF 186

  Fly   267 GHPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVP----TERAGFG 327
            |.    |.|...|.::.:|:      |.:|          :|.|:....|:.:.    |.:..|.
Worm   187 GE----ITLRYLIFFECFMT------FFLP----------LVLTVITDFSVLIMRNPCTSKNAFT 231

  Fly   328 AAPA---------RRASSRGIIPRAKV--------KTVKMTLTIVFVFIICWSPYIIFDLLQVFG 375
            ...|         ...|...|:.::|:        ..::..|.:..|.::...|.....|:..|.
Worm   232 LISADEIVHHESTDEKSPLKIVHKSKIMLDIRRRNDAIRRCLLLATVTLLLNLPNYSLQLIDEFY 296

  Fly   376 QIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKS 431
            ....|:.......|::        |:.::|.::       |.:||....:..|.|:
Worm   297 HFRESEDLADRRRFVR--------ADAIVYIIY-------LLQFPTVPLYMYCLKT 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	65/345 (19%)
		TM helix 1	126..150	CDD:320325	9/32 (28%)
		TM helix 2	159..182	CDD:320325	5/25 (20%)
		TM helix 3	197..219	CDD:320325	9/24 (38%)
		TM helix 4	240..256	CDD:320325	2/17 (12%)
		TM helix 5	282..305	CDD:320325	3/22 (14%)
		TM helix 6	348..370	CDD:320325	3/21 (14%)
		TM helix 7	384..409	CDD:320325	3/24 (13%)
C04C3.6	NP_500342.1	7tm_GPCRs	<96..>221	CDD:391938	30/147 (20%)
		TM helix 3	100..130	CDD:341315	11/32 (34%)
		TM helix 4	142..162	CDD:341315	2/19 (11%)
		TM helix 5	193..221	CDD:341315	7/43 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24224
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100