DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCAP-R and oxtra

DIOPT Version :9

Sequence 1:	NP_001368957.1	Gene:	CCAP-R / 2768688	FlyBaseID:	FBgn0039396	Length:	521	Species:	Drosophila melanogaster
Sequence 2:	NP_001186299.1	Gene:	oxtra / 100001530	ZFINID:	ZDB-GENE-110805-2	Length:	388	Species:	Danio rerio

Alignment Length:	388	Identity:	121/388 - (31%)
Similarity:	188/388 - (48%)	Gaps:	30/388 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ETGGNSTSSDPGEFDNLNSFYFYETEQFA-----VLWILFTVIVLGNSAVLFVMFINKNRKSRMN 159
            |:..|:|:...|....:|.  ....|:.|     ||.::..:.:.||..||..:...|:.:|||.
Zfish    15 ESSRNATNETYGVNQTVNP--LKRNEEVAKVEVTVLALVLFLALAGNLCVLIAIHTAKHSQSRMY 77

  Fly   160 YFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDA 224
            ||:|.|::|||.|.:..||..:||.||..:...::.|:.:::.|....::|||:||.|||||..|
Zfish    78 YFMKHLSIADLVVAVFQVLPQLIWDITFRFYGPDILCRLVKYLQTVGMFASTYMLVLMSIDRCMA 142

  Fly   225 ITHPMNFSKSWKRARHLVAGAWLISALFSLPILVLYEEKLI-QGHPQCWIELGSPIAWQVYMSLV 288
            |..|:. |...::.|..|..:|.:|.|||:|.:.::..:.: .|...||.:...|...:.|::.:
Zfish   143 ICQPLR-SLHKRKDRCYVICSWALSLLFSIPQVYIFSLREVGSGVYDCWGDFVQPWGAKAYITWI 206

  Fly   289 SATLFAIPALIISACYAIIVKTIW-------AKGSIFVPTERAGFGAAPARRASSRGIIPRAKVK 346
            |.|::.||..|:|.||.:|...||       .:......|.:|..|.|.| |.||..:|.:||:.
Zfish   207 SLTIYIIPVTILSVCYGLISFKIWQNFKRKTKRDQCITLTPKASKGNALA-RVSSVKLISKAKIT 270

  Fly   347 TVKMTLTIVFVFIICWSPYIIFDLLQVFG-QIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSS 410
            |||||..||..:|:||:|:....:...:. :.|.......|:..   ||.|||..||.||..|:.
Zfish   271 TVKMTFVIVLAYIVCWTPFFSVQMWSAWDPEAPREAMPFIISML---LASLNSCCNPWIYMFFAG 332

  Fly   411 QVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTN 473
            .:|..|.:.     ..||...|..:||.........|..||    .|.....|.|:||..:|:
Zfish   333 HLFHDLKQN-----LFCCSTLYLKSSQCRYDPEQDSRKSNS----STYVIKSTSSQRSITQTS 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCAP-R	NP_001368957.1	7tmA_NPSR	124..416	CDD:320325	101/305 (33%)
		TM helix 1	126..150	CDD:320325	7/28 (25%)
		TM helix 2	159..182	CDD:320325	10/22 (45%)
		TM helix 3	197..219	CDD:320325	7/21 (33%)
		TM helix 4	240..256	CDD:320325	6/15 (40%)
		TM helix 5	282..305	CDD:320325	8/22 (36%)
		TM helix 6	348..370	CDD:320325	10/21 (48%)
		TM helix 7	384..409	CDD:320325	10/24 (42%)
oxtra	NP_001186299.1	7tm_1	58..327	CDD:278431	93/273 (34%)
oxtra	NP_001186299.1	7tm_4	59..>241	CDD:304433	61/182 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	163	1.000	Domainoid score	I3913
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I4004
OMA	1	1.010	-	-		QHG45270
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24293
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.060