Protein Alignment mld and ZNF764

DIOPT Version :10

• Sequence 1: NP_001247289.1
• Gene: mld / 2768685
• FlyBaseID: FBgn0263490
• Length: 1965
• Species: Drosophila melanogaster
• Sequence 2: NP_219363.2
• Gene: ZNF764 / 92595
• HGNCID: 28200
• Length: 408
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 81/263 - (30%)
• Similarity: 115/263 - (43%)
• Gaps: 42/263 - (15%)

  Fly  1643 QSEP-DSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPS-SSPSSSTVDHIPPASP--------- 1696
            |::| ||....::.::.|.     |.|....|||:.||. .||.:      |.|.|
Human   100 QTDPADSRNKKKERQREGT-----GALEKPDPVAAGSPGLKSPQA------PSAGPPYGWEQLSK 153

  Fly  1697 ----ATPASPAPPPSPAVASTVQVSELRTSHHCLYCEERFTNEISLKKHHQLAHGALTTMPYVCT 1757
                ..|:..|.||.|....         .|.|..|.:.|....:|.:|   .:......|:.||
Human   154 APHRGRPSLCAHPPVPRADQ---------RHGCYVCGKSFAWRSTLVEH---VYSHTGEKPFHCT 206

  Fly  1758 ICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFG 1822
            .|.:|:...::|.:|...|..| ||:.|..|...|.:.|.||.| :.||...||:.|.:||::|.
Human   207 DCGKGFGHASSLSKHRAIHRGE-RPHRCLECGRAFTQRSALTSH-LRVHTGEKPYGCADCGRRFS 269

  Fly  1823 TESALKTHIKFH-GELGYQCDGCDRTFEYLKELRKHRRTHS-EMFYKCKFCPSSFMRFTNFRAHM 1885
            ..|||..|.:.| ||..:.|..|.|.|.|..:||:|.|||: |..|.|..|...|.:.:...||.
Human   270 QSSALYQHRRVHSGETPFPCPDCGRAFAYPSDLRRHVRTHTGEKPYPCPDCGRCFRQSSEMAAHR 334

  Fly  1886 KTH 1888
            :||
Human   335 RTH 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mld	NP_001247289.1	zf-AD	186..255	CDD:214871
		PAT1	<959..>1109	CDD:401645
		C2H2 Zn finger	1365..1388	CDD:275368
		C2H2 Zn finger	1396..1416	CDD:275368
		C2H2 Zn finger	1424..1445	CDD:275368
		C2H2 Zn finger	1725..1746	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1756..1776	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1785..1806	CDD:275368	7/20 (35%)
		zf-C2H2	1812..1834	CDD:395048	8/21 (38%)
		C2H2 Zn finger	1814..1834	CDD:275368	8/19 (42%)
		zf-C2H2	1839..1861	CDD:395048	9/21 (43%)
		C2H2 Zn finger	1841..1861	CDD:275368	9/19 (47%)
		zf-C2H2	1866..1888	CDD:395048	6/21 (29%)
		C2H2 Zn finger	1868..1888	CDD:275368	5/19 (26%)
ZNF764	NP_219363.2	KRAB	26..85	CDD:214630
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..167		19/77 (25%)
		C2H2 Zn finger	177..197	CDD:275368	5/22 (23%)
		zf-H2C2_2	190..212	CDD:463886	6/24 (25%)
		C2H2 Zn finger	205..225	CDD:275368	6/19 (32%)
		COG5048	229..>294	CDD:227381	26/65 (40%)
		C2H2 Zn finger	233..253	CDD:275368	7/20 (35%)
		C2H2 Zn finger	261..281	CDD:275368	8/19 (42%)
		C2H2 Zn finger	289..309	CDD:275368	9/19 (47%)
		zf-H2C2_2	301..326	CDD:463886	11/24 (46%)
		C2H2 Zn finger	317..337	CDD:275368	5/19 (26%)
		zf-H2C2_2	333..352	CDD:463886	3/5 (60%)
		C2H2 Zn finger	345..365	CDD:275368