Protein Alignment mld and CG1602

DIOPT Version :10

• Sequence 1: NP_001247289.1
• Gene: mld / 2768685
• FlyBaseID: FBgn0263490
• Length: 1965
• Species: Drosophila melanogaster
• Sequence 2: NP_610291.2
• Gene: CG1602 / 35684
• FlyBaseID: FBgn0033186
• Length: 577
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 129/611 - (21%)
• Similarity: 215/611 - (35%)
• Gaps: 129/611 - (21%)

  Fly  1363 LKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPMAFAGRTKRSQHI--------LSHHVV 1419
            ::|.:|......:...|:..||.::|..|........|:  ...:..|.|:        ....:.
  Fly    18 MRCSYCPTDVEVAQWQEFVLHIRNVHSKVRSMEDDFEPV--GENSTESGHVDPPEEKPQAEESIF 80

  Fly  1420 QQYQC--GQCSHV-FPAQKALDVHIQRFHMTLKTDPSGAVKVEDVQLQITSERRPRGRPYKPRLQ 1481
            ||.:.  |.|..: ..|.::.....:...::|.||...:|:.||              |.:|.|.
  Fly    81 QQDESADGACVQLHIDAVRSSTNETEESDVSLVTDEEESVQDED--------------PSEPALD 131

  Fly  1482 LQQHQLQPQQKLQVQQHQQQQKALQQLP-QAQH-------HQQQQQPQLQQEVLQQVQ-QLQVQV 1537
            ....:..|..|......::..:.::.:. ..:|       |...::|:..:|.|:::. .|:..|
  Fly   132 DANLKTTPTYKFHPSFFRRDHRTIKFIEIYKEHPCLWNPAHSDYKEPKKCKEALKRMAIDLEATV 196

  Fly  1538 Q------------PQQHQQ----HQQVLQVQQPQQQPLMQPQSPHPSTVEMQASPTTPRKILCC- 1585
            .            .:.|.|    |::|:..:|       :|||...|..:           |||
  Fly   197 SVFLNEMALKLAIKKVHMQFNTVHKRVVSGKQ-------KPQSLAFSIYK-----------LCCF 243

  Fly  1586 ----PDCEDCTSGH------SHANEQFEELQTLQAP-PTVLTPPSTIVSVPSPQPMVY---SQHI 1636
                .|.|..|:..      |..|:...:|..:.|. |.:........|..|.:...|   :..|
  Fly   244 LNASNDEEGATNNEKIKLDFSKKNKLTTDLIEMYANFPQLYDSNHKEFSNMSSRKQAYESMAAEI 308

  Fly  1637 TMPSPEQSEPD---STTTLRQY----RKRGVIVGPQGPLHLATPVASPSPSSSPSSSTV------ 1688
            ::|:.:.:..|   :...|||:    .|..:..|.... .....|....|:.......|
  Fly   309 SVPNVDINSDDIFRAIQNLRQWYYKNTKHAIYAGSTAE-KFYLEVCRFMPAKMYKQRLVCEFCHQ 372

  Fly  1689 ----DHIPPASPATPASPAPPPSPAVASTVQVSELRTSHHCLYCEERFTNEISLKKHHQLAHGAL 1749
                ||:..:.              :.....:.||  ...|..|:..|.....|..|.|..|...
  Fly   373 ITSSDHVLQSH--------------IFKAHNIGEL--PFKCTLCDRSFVGRCELANHIQRVHIGK 421

  Fly  1750 TTMPYVCTICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTC 1814
            |   :.||.|:|.:.:.:.|..|:.:| ...:||.|..|...|...||:|||...:|...:...|
  Fly   422 T---HKCTHCERSFAVMSDLQLHIRTH-TGHKPYVCEHCGKAFRLRSQMTLHVTAIHTKIRAFKC 482

  Fly  1815 DECGKQFGTESALKTHIKFHGELGYQ-CDGCDRTFEYLKELRKHRRTHSEM-FYKCKFCPSSFMR 1877
            ..|.|.|..:..|..|||.|..:..: |..|.:.|.....|.:||:.|||: .:.||.|.|.|.:
  Fly   483 TMCPKDFVKKVDLSDHIKGHLNIRDKICSVCGKGFTSCHALIRHRQIHSEVKKFVCKLCDSRFSQ 547

  Fly  1878 FTNFRAHMK-THLPLGVFRNEDAASK 1902
            |.....||| ||   .:.||.....|
  Fly   548 FVGLNTHMKRTH---NILRNNSQKGK 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mld	NP_001247289.1	zf-AD	186..255	CDD:214871
		PAT1	<959..>1109	CDD:401645
		C2H2 Zn finger	1365..1388	CDD:275368	5/22 (23%)
		C2H2 Zn finger	1396..1416	CDD:275368	3/27 (11%)
		C2H2 Zn finger	1424..1445	CDD:275368	3/23 (13%)
		C2H2 Zn finger	1725..1746	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1756..1776	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1785..1806	CDD:275368	8/20 (40%)
		zf-C2H2	1812..1834	CDD:395048	8/21 (38%)
		C2H2 Zn finger	1814..1834	CDD:275368	8/19 (42%)
		zf-C2H2	1839..1861	CDD:395048	6/22 (27%)
		C2H2 Zn finger	1841..1861	CDD:275368	6/19 (32%)
		zf-C2H2	1866..1888	CDD:395048	9/22 (41%)
		C2H2 Zn finger	1868..1888	CDD:275368	9/20 (45%)
CG1602	NP_610291.2	MADF_DNA_bdg	157..244	CDD:463144	19/104 (18%)
		MADF_DNA_bdg	273..356	CDD:463144	15/83 (18%)
		C2H2 Zn finger	367..388	CDD:275368	2/34 (6%)
		C2H2 Zn finger	397..418	CDD:275368	6/20 (30%)
		C2H2 Zn finger	425..445	CDD:275368	6/19 (32%)
		zf-H2C2_2	437..460	CDD:463886	7/23 (30%)
		C2H2 Zn finger	453..470	CDD:275368	7/16 (44%)
		C2H2 Zn finger	482..502	CDD:275368	8/19 (42%)
		C2H2 Zn finger	510..530	CDD:275368	6/19 (32%)
		C2H2 Zn finger	538..559	CDD:275368	9/20 (45%)