Protein Alignment mld and ZNF629

DIOPT Version :10

• Sequence 1: NP_001247289.1
• Gene: mld / 2768685
• FlyBaseID: FBgn0263490
• Length: 1965
• Species: Drosophila melanogaster
• Sequence 2: NP_001073886.1
• Gene: ZNF629 / 23361
• HGNCID: 29008
• Length: 869
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 106/384 - (27%)
• Similarity: 144/384 - (37%)
• Gaps: 90/384 - (23%)

  Fly  1579 PRKILCCPDCE-------DCTSGHSHANEQFEELQTLQAPPTVLTPPSTIVSVPSPQPMVYSQHI 1636
            |...|..||.:       |...|....||:....|.......::..|:     .||:    |:..
Human     3 PETALWGPDLQGPEQSPNDAHRGAESENEEESPRQESSGEEIIMGDPA-----QSPE----SKDS 58

  Fly  1637 TMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPSSSPSSS--------------- 1686
            |..|.|:|..|.:..    :.....:|...||....|:..|:|...|:.|
Human    59 TEMSLERSSQDPSVP----QNPPTPLGHSNPLDHQIPLDPPAPEVVPTPSDWTKACEASWQWGAL 119

  Fly  1687 TVDHIPPASPATPAS--------PAPPPSPAVA-----STVQVSEL---------RTSHHCLYCE 1729
            |..:.||..||...|        ||....|.:.     |..|.|:|         ...:.|..|.
Human   120 TTWNSPPVVPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECG 184

  Fly  1730 ERFTNEISLKKH---------------------------HQLAHGALTTMPYVCTICKRGYRMRT 1767
            :.||....|.:|                           ||..|..  ..||.||.|::.:...|
Human   185 KSFTQSSHLVQHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTG--EKPYKCTECEKAFTQST 247

  Fly  1768 ALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIK 1832
            .|.:|..||..| :||:|..||..|.|.|.|..|:.| |...||:.|.||||:||....|..|.|
Human   248 NLIKHQRSHTGE-KPYKCGECRRAFYRSSDLIQHQAT-HTGEKPYKCPECGKRFGQNHNLLKHQK 310

  Fly  1833 FH-GELGYQCDGCDRTFEYLKELRKHRRTHS-EMFYKCKFCPSSFMRFTNFRAHMKTHL 1889
            .| ||..|:|..|.::|....||.:|:|||: |..|:|..|..||...:....|.:|||
Human   311 IHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHL 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mld	NP_001247289.1	zf-AD	186..255	CDD:214871
		PAT1	<959..>1109	CDD:401645
		C2H2 Zn finger	1365..1388	CDD:275368
		C2H2 Zn finger	1396..1416	CDD:275368
		C2H2 Zn finger	1424..1445	CDD:275368
		C2H2 Zn finger	1725..1746	CDD:275368	8/47 (17%)
		C2H2 Zn finger	1756..1776	CDD:275368	6/19 (32%)
		C2H2 Zn finger	1785..1806	CDD:275368	9/20 (45%)
		zf-C2H2	1812..1834	CDD:395048	10/21 (48%)
		C2H2 Zn finger	1814..1834	CDD:275368	10/19 (53%)
		zf-C2H2	1839..1861	CDD:395048	8/21 (38%)
		C2H2 Zn finger	1841..1861	CDD:275368	7/19 (37%)
		zf-C2H2	1866..1888	CDD:395048	6/21 (29%)
		C2H2 Zn finger	1868..1888	CDD:275368	5/19 (26%)
ZNF629	NP_001073886.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..105		25/114 (22%)
		PTZ00449	<3..>149	CDD:185628	34/158 (22%)
		zf-C2H2	150..172	CDD:395048	4/21 (19%)
		C2H2 Zn finger	152..172	CDD:275368	4/19 (21%)
		zf-C2H2	179..200	CDD:395048	6/20 (30%)
		C2H2 Zn finger	180..200	CDD:275368	6/19 (32%)
		COG5048	204..512	CDD:227381	61/170 (36%)
		C2H2 Zn finger	208..228	CDD:275368	2/19 (11%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		C2H2 Zn finger	264..284	CDD:275368	9/20 (45%)
		C2H2 Zn finger	292..312	CDD:275368	10/19 (53%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		C2H2 Zn finger	348..368	CDD:275368	5/19 (26%)
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	571..591	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	607..651
		C2H2 Zn finger	664..684	CDD:275368
		C2H2 Zn finger	716..736	CDD:275368
		C2H2 Zn finger	770..790	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	787..837
		C2H2 Zn finger	844..864	CDD:275368