DRSC/TRiP Functional Genomics Resources

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Protein Alignment mld and Zfp770

DIOPT Version :9

Sequence 1:NP_001247289.1 Gene:mld / 2768685 FlyBaseID:FBgn0263490 Length:1965 Species:Drosophila melanogaster
Sequence 2:NP_780675.1 Gene:Zfp770 / 228491 MGIID:2445100 Length:705 Species:Mus musculus


Alignment Length:299 Identity:68/299 - (22%)
Similarity:105/299 - (35%) Gaps:69/299 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1725 CLYCEERFTNEISLKKHHQLAHGALTTMPYVCTICKRGYRMRTALHRHMESHDVEGRPYECNICR 1789
            |..|.:.|.....|.:|:.:..|   ..|:.|.:|.:.:|....|.||..:|::   |:.||||:
Mouse    33 CNICFKHFETPSKLARHYLIHTG---QKPFECDVCHKNFRQLVHLERHQLTHNL---PFSCNICQ 91

  Fly  1790 VRFPRPSQLTLH-------------------------------------KITVHLLSKP------ 1811
            ..|........|                                     :..:|..||.      
Mouse    92 RHFKNLKTFVKHQQLHNESYHNDVKVRRLLETKQEKPVYGMCNTFTADERWALHPCSKSDATYST 156

  Fly  1812 -------HTCDECGKQFGTESALKTHIKFH-GELGYQCDGCDRTFEYLKELRKHRRTHS-EMFYK 1867
                   |.|..|||.|.::|.|..|...| |:..::|..|.::|.....|:.|:.||| |..::
Mouse   157 TKRRKNIHACTICGKMFPSQSKLDRHSLIHTGQRPFKCVLCSKSFRQSTHLKIHQLTHSEERPFQ 221

  Fly  1868 CKFCPSSFMRFTNFRAHMKTHLPLGVFRNEDAASKSPSN----NNSHASSDKLE--NPATPIEET 1926
            |.||...|...:....|.:.|......:|.....|||.:    |..:|..|..|  :.....|..
Mouse   222 CCFCQKGFKIQSKLLKHKQIHTRNKTLQNLPLKVKSPESCPLPNKLNAKQDAFESGDMGESEENN 286

  Fly  1927 PLTPMSSGGHLYHSPDEYPNSVESCAGNSVALESYATTP 1965
            ||...|    :|..|.:. :..|.|..:...|..:...|
Mouse   287 PLDVHS----IYIVPFQC-SECEECFESEQILNGHKCLP 320

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mldNP_001247289.1 zf-AD 186..255 CDD:214871
C2H2 Zn finger 1365..1388 CDD:275368
C2H2 Zn finger 1396..1416 CDD:275368
C2H2 Zn finger 1424..1445 CDD:275368
C2H2 Zn finger 1725..1746 CDD:275368 5/20 (25%)
C2H2 Zn finger 1756..1776 CDD:275368 6/19 (32%)
C2H2 Zn finger 1785..1806 CDD:275368 6/57 (11%)
C2H2 Zn finger 1814..1834 CDD:275368 8/19 (42%)
zf-C2H2 1839..1861 CDD:278523 5/21 (24%)
C2H2 Zn finger 1841..1861 CDD:275368 5/19 (26%)
C2H2 Zn finger 1868..1888 CDD:275368 5/19 (26%)
Zfp770NP_780675.1 C2H2 Zn finger 33..53 CDD:275368 5/19 (26%)
zf-H2C2_2 46..70 CDD:404364 6/26 (23%)
C2H2 Zn finger 61..81 CDD:275368 6/19 (32%)
C2H2 Zn finger 87..107 CDD:275368 6/19 (32%)
C2H2 Zn finger 166..186 CDD:275368 8/19 (42%)
zf-H2C2_2 179..203 CDD:404364 7/23 (30%)
C2H2 Zn finger 194..214 CDD:275368 5/19 (26%)
C2H2 Zn finger 222..242 CDD:275368 5/19 (26%)
C2H2 Zn finger 487..507 CDD:275368
zf-H2C2_2 500..524 CDD:404364
C2H2 Zn finger 515..535 CDD:275368
C2H2 Zn finger 642..662 CDD:275368
zf-H2C2_2 655..679 CDD:404364
C2H2 Zn finger 670..690 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24376
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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