Protein Alignment Myo95E and MYA1

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_173201.2
• Gene: MYA1 / 838333
• AraportID: AT1G17580
• Length: 1520
• Species: Arabidopsis thaliana
• Alignment Length: 1266
• Identity: 293/1266 - (23%)
• Similarity: 482/1266 - (38%)
• Gaps: 400/1266 - (31%)

  Fly     6 GTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYH---HISEHSLDNVRNYGDKGI 67
            |..|...|..|.|...:.|:..||:.:.||||.|..::|:||:.   ||.|  .|.:..|....:
plant    60 GVDDMTKLSYLHEPGVLRNLETRYELNEIYTYTGNILIAVNPFQRLPHIYE--TDMMEQYKGIAL 122

  Fly    68 FQLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLR 132
            .:|.||::.:.:.||:::.::.::..:|::||||||||||.||::.:|..:..||
plant   123 GELSPHVFAIGDAAYRAMINEGKNNSILVSGESGAGKTETTKMLMRYLAFLGGRS---------- 177

  Fly   133 KQSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIE 197
                                                                             
plant   178 ----------------------------------------------------------------- 177

  Fly   198 RQSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPK 262
                                   .:.|
plant   178 -----------------------GVEG-------------------------------------- 181

  Fly   263 YAVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHS 327
                            :.|..|.||                     :||.
plant   182 ----------------RTVEQQVLE---------------------SNPV--------------- 194

  Fly   328 TESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRM 392
                                                                             
plant   195 ----------------------------------------------------------------- 194

  Fly   393 RECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTR---ITDPII 454
                      |||.|||.||:||||||:||..:|:.|..|...|..|..|:||::|   |:||
plant   195 ----------LEAFGNAKTLRNNNSSRFGKFVEIQFDKNGRISGAAIRTYLLERSRVCQISDP-- 247

  Fly   455 GERNFHIFYQLLLGADLQLLKSLKLYRNVEKYELLRNTTAME----EDRMNFHYTKRSLDVLGLS 515
             |||:|.|| ||..|..:.:|..|| .|..|:..|..::..:    :|...:..|:|::||:|:|
plant   248 -ERNYHCFY-LLCAAPPEDIKKYKL-ENPHKFHYLNQSSCYKLDGVDDASEYLETRRAMDVVGIS 309

  Fly   516 CEESNSIFRVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANS 580
            .||..:||||:|.:|.|||..|.....||       |:|.:.:::...|||.|::|   :..|.|
plant   310 NEEQEAIFRVVAAILHLGNIDFGKGEEID-------SSVIKDKDSRSHLNMAAELL---MCNAQS 364

  Fly   581 TNSA---------QEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKSTQREKN-LAL 635
            ...|         :|.:...:|...|..:|:||.:|:||.||.|:|||||.|:....|.|: :.:
plant   365 LEDALIRRVMVTPEEIITRTLDPDNAIASRDTLAKTIYSHLFDWIVNKINTSIGQDPRSKSIIGV 429

  Fly   636 LDFYGFEALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELID 700
            ||.||||:...||||||.||::.||:.|:|..||.:.|||.|.:|.:.||.|::.||:.:.|||:
plant   430 LDIYGFESFKCNSFEQFCINFTNEKLQQHFNQHVFKMEQEEYTKEEIAWSYIEFIDNQDVLELIE 494

  Fly   701 KPSYGILSLINEPHL---NSNDALLLRVQQCCAGHPNFMTTGSNSMCFQIRHYASVVNYSIHRFL 762
            |...||:||::|..:   ::::....::.|....|..|.....:...|.|.|||..|.|..:.|:
plant   495 KKPGGIISLLDEACMFPKSTHETFSQKLFQTFKEHERFAKPKLSRTDFTISHYAGEVTYQSNHFI 559

  Fly   763 EKNSDMLPKYISAAFYQSKLSLVQSLFPEGNPRRQVTKKPSTLSSNIRTQLQTLLAIVKHRRSHY 827
            :||.|.:.....|.|..|....|..||...:.....:.|.|::.|..:.||.:|:..:.....||
plant   560 DKNKDYIVAEHQALFTASNCKFVAGLFHALHEDSSRSSKFSSIGSRFKQQLHSLMESLNGTEPHY 624

  Fly   828 VFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNSLTWPHFH 892
            :.|||||...:|..|:...|.||:|...::..:.:...|:...|....|..|:.||.    |...
plant   625 IRCIKPNNVLKPGIFENFNVIHQLRCGGVLEAIRISCAGYPTRLAFYDFLDRFGLLA----PEVL 685

  Fly   893 GGSQVEGIA--LIIRNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQTMFRMYH 955
            .|:..:.:|  :|:....|  .::.||...:|:|:.: :.||:..|...:...|.:||..||...
plant   686 EGNYDDKVACQMILDKKSL--TDYQIGKTKIFLRAGQ-MAELDARRAEVLGNAARVIQRQFRTCM 747

  Fly   956 ARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKRQVRWAIDIIG 1020
            |||.::.:|::.:::.|..|.                    .:||..::.|:    :..|...:.
plant   748 ARKNYRSIRNAAIVLQSFLRG--------------------EIARAVHKKLR----IEAAALRVQ 788

  Fly  1021 RYYRQWKIRQFLLT--------------------IPLRLPPNTLSPLSTEWPVAPAFLADASRHL 1065
            :.:|::..|:..:|                    ..||........|...|....||
plant   789 KNFRRYVDRKSFVTTRSSTIVLQTGLRAMIARSEFRLRRQRKAAIVLQAHWRGRQAF-------- 845

  Fly  1066 RSIYHR-----------WKCYIYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFVGDYV 1119
             |.|.|           |:|.:.|......   :|..:.|.::  ||.|....:.|      :.:
plant   846 -SYYTRLQKAAIVTQCAWRCRLARRELRML---KMAARDTGAL--KDAKNKLEQRV------EEL 898

  Fly  1120 RLRHNQQWKKICAETNDQYVVFADIINKIARSSGKFVPILLVL-STSSLLLLDQRTLQIKYRVPA 1183
            .||.:.: |::..:..:..|      .::|:.......:.|.| .|:::::.:|...    ||..
plant   899 SLRLHLE-KRLRTDLEEAKV------QEVAKLQEALHTMRLQLKETTAMVVKEQEAA----RVAI 952

  Fly  1184 SEIYRMSLSP-YLDDIAVFHVKASEFGRKKG 1213
            .|...::..| .::|.......::|..|.||
plant   953 EEASSVNKEPVVVEDTEKIDSLSNEIDRLKG 983

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	41/119 (34%)
		Motor_domain	<403..937	CDD:473979	189/555 (34%)
		Myosin_TH1	1092..1288	CDD:461801	23/124 (19%)
MYA1	NP_173201.2	Myosin_N	8..47	CDD:460670
		MYSc_Myo11	73..717	CDD:276835	230/929 (25%)
		sbcc	<718..>1117	CDD:129705	57/322 (18%)
		COG1340	<868..1047	CDD:440951	25/138 (18%)
		MyosinXI_CBD	1099..1486	CDD:271259