Protein Alignment Myo95E and Myo1c

DIOPT Version :9

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_038942736.1
• Gene: Myo1c / 65261
• RGDID: 620443
• Length: 1063
• Species: Rattus norvegicus
• Alignment Length: 1335
• Identity: 351/1335 - (26%)
• Similarity: 552/1335 - (41%)
• Gaps: 376/1335 - (28%)

  Fly     5 IGTWDSVLLENL-SEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIF 68
            :|..|.|||||. ||.:||.|:.:|::.:.||||||..:|::|||..:..::..::..|.....:
  Rat    46 VGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYTRQHMERYRGVSFY 110

  Fly    69 QLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRK 133
            ::|||::.:.:..|::|:.:..||.|:::|||||||||..|.::.|.
  Rat   111 EVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFY------------------ 157

  Fly   134 QSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIER 198
                                                                             
  Rat   158 ----------------------------------------------------------------- 157

  Fly   199 QSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKY 263
                                                                             
  Rat   158 ----------------------------------------------------------------- 157

  Fly   264 AVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHST 328
                                                       |.|.|| |.||..   :|....
  Rat   158 -------------------------------------------AETCPA-PERGGA---VRDRLL 175

  Fly   329 ESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMR 393
            :|.|
  Rat   176 QSNP------------------------------------------------------------- 179

  Fly   394 ECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERN 458
                    .|||.|||.||:|:||||:||..|::.||||.|:|.||..|:|||:|:.....||||
  Rat   180 --------VLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERN 236

  Fly   459 FHIFYQLLLGADLQLLKSLKLYRNVEKY-ELLRNTTAME---EDRMNFHYTKRSLDVLGLSCEES 519
            ||:|||||.|.:.:.|:.|.|.||.:.| .|::...|..   .|:.::...:::|.|:..:.:|.
  Rat   237 FHVFYQLLEGGEEEALRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALSVIDFTEDEV 301

  Fly   520 NSIFRVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANSTNSA 584
            ..:..::|.||.|||..|.    .|.....||:...:::...:||.:|...|...||........
  Rat   302 EDLLSIVASVLHLGNIHFA----ADEDSNAQVTTENQLKYLTRLLGVEGTTLREALTHRKIIAKG 362

  Fly   585 QEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKSTQREKN-------LALLDFYGFE 642
            :|.:. .::..|||..|:.|.:.:|||.|||||.|||.||.|...|..       |.|||.||||
  Rat   363 EELLS-PLNLEQAAYARDALAKAVYSRTFTWLVRKINRSLASKDAESPSWRSTTVLGLLDIYGFE 426

  Fly   643 ALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYGIL 707
            ...|||||||.|||..||:.|.|:...|:||||.|..||:.|..:.||:|:.||:|:::...||:
  Rat   427 VFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGII 491

  Fly   708 SLINEPHLNSNDA----LLLRVQQCCAGHPNFMT-------------TGSNSMCFQIRHYASVVN 755
            |:::|..|...:|    .|.:::.....||:|:|             .|.    |::.|||..|.
  Rat   492 SILDEECLRPGEATDLTFLEKLEDTIKHHPHFLTHKLADQKTRKSLDRGE----FRLLHYAGEVT 552

  Fly   756 YSIHRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEGNPRRQVTKKPSTLSSNIRTQLQTLLAIV 820
            ||:..||:||:|:|.:.:......|...::...|.:.....:  |:|.|:::..:..|..|:.|:
  Rat   553 YSVTGFLDKNNDLLFRNLKETMCSSTNPIMAQCFDKSELSDK--KRPETVATQFKMSLLQLVEIL 615

  Fly   821 KHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNS 885
            :.:...|:.|||||:.|||.:||..|::|||:|:.||..:.:.|.|..|...:..|..|||.|..
  Rat   616 RSKEPAYIRCIKPNDAKQPGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRKYEAFLQRYKSLCP 680

  Fly   886 LTWPHFHGGSQVEGIALIIRNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQTM 950
            .|||.:.|..| :|:|:::|:|.....|:.:|...:|:|.|:|::..|....:|...||..||..
  Rat   681 ETWPVWTGRPQ-DGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDSLEVRRQSLATKIQAA 744

  Fly   951 FRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKRQVRWA 1015
            :|.:|.|::|.|::.|.:.|.|.||         ...|||      :.|:.           :||
  Rat   745 WRGFHWRQKFLRVKRSAICIQSWWR---------GTLGRR------KAAKR-----------KWA 783

  Fly  1016 IDIIGRYYRQWKIR-----------------QFLLTIPLRLPPNTLSPLSTEWPVAPAFLADASR 1063
            ...|.|..|.:.:|                 .|||.:..:||.|.   |.|.||..|..|.:||.
  Rat   784 AQTIRRLIRGFILRHAPRCPENAFFLDHVRTSFLLNLRRQLPRNV---LDTSWPTPPPALREASE 845

  Fly  1064 HLRSIYHR---WKCYIYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFVGDYVRLRHNQ 1125
            .||.:..:   ||   |..|.....:.::::|..||.|||.:|.:|.:||...|:.  .||...:
  Rat   846 LLRELCMKNMVWK---YCRSISPEWKQQLQQKAVASEIFKGKKDNYPQSVPRLFIS--TRLGTEE 905

  Fly  1126 QWKKICAETNDQYVVFADIINKIARSSGKFVPILLVLSTSSLLLLDQRTLQIKYRVPASEIYRMS 1190
            ...::......:.:.:|..:.|..|...|.....|:|:.|::::::.  .::|.|:..:.:..:|
  Rat   906 ISPRVLQALGSEPIQYAVPVVKYDRKGYKPRSRQLLLTPSAVVIVED--AKVKQRIDYANLTGIS 968

  Fly  1191 LSPYLDDIAVFHVKASEFGRKKGDFVFQTGHVIEIVTKMFLVIQNATGKPPEIHISTEFEANFGQ 1255
            :|...|.:.|.||: .|..::|||.|.|:.||||.:||..|......            ..|..|
  Rat   969 VSSLSDSLFVLHVQ-REDSKQKGDVVLQSDHVIETLTKTALSADRVN------------NININQ 1020

  Fly  1256 QTVIFSFKYG--GMSDLAQGPPKVTRKANRMEIIV 1288
            .::.|:...|  |:.|...|...:..||....:.|
  Rat  1021 GSITFAGGPGRDGIIDFTSGSELLITKAKNGHLAV 1055

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	19..>118	CDD:277568	34/98 (35%)
		Motor_domain	403..924	CDD:277568	198/548 (36%)
		Myosin_TH1	1092..1267	CDD:283635	45/176 (26%)
Myo1c	XP_038942736.1	MYSc_Myo1	62..718	CDD:276829	242/931 (26%)
		IQ	756..776	CDD:197470	9/34 (26%)
		Myosin_TH1	874..1055	CDD:399188	50/197 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105718at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720