Protein Alignment Myo95E and myo1ca

DIOPT Version :9

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_005165404.1
• Gene: myo1ca / 567536
• ZFINID: ZDB-GENE-070705-190
• Length: 1045
• Species: Danio rerio
• Alignment Length: 1331
• Identity: 364/1331 - (27%)
• Similarity: 560/1331 - (42%)
• Gaps: 377/1331 - (28%)

  Fly     5 IGTWDSVLLEN-LSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIF 68
            :|..|.:|||| .||.:||.|:.:||:...||||||:.:|::|||..:..:|..|:..:.....:
Zfish    28 VGVQDFLLLENHNSEAAFIENLRRRYREGLIYTYIGSVLVSVNPYKELEIYSKQNMERHRGVNFY 92

  Fly    69 QLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRK 133
            ::.|||:.|.:.:|::|:.:..|||:|::|||||||||..|.|:.:.|||     ||
Zfish    93 EISPHIFALADNSYRALRTERRDQCILISGESGAGKTEASKKILQYYTHI-----CP-------- 144

  Fly   134 QSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIER 198
                                                                             
Zfish   145 ----------------------------------------------------------------- 144

  Fly   199 QSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKY 263
                                                                             
Zfish   145 ----------------------------------------------------------------- 144

  Fly   264 AVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHST 328
                                                        |.|..|        .:|:...
Zfish   145 --------------------------------------------TRNNTH--------TIRERLL 157

  Fly   329 ESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMR 393
            :|.|
Zfish   158 QSNP------------------------------------------------------------- 161

  Fly   394 ECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERN 458
                    .|||.|||.||:|:||||:||..||:.|:||.|:|.||.:|:|||:|:.....||||
Zfish   162 --------VLEAFGNAKTLRNDNSSRFGKYMDIQFDYKGAPIGGHILNYLLEKSRVAHQNHGERN 218

  Fly   459 FHIFYQLLLGADLQLLKSLKLYR-NVEKYELLRN----TTAMEEDRMNFHYTKRSLDVLGLSCEE 518
            ||||||||.|.:..|||.|.|.: |.:.|..|..    ..:...|:..:...:.:|.::|...||
Zfish   219 FHIFYQLLEGGEDLLLKRLGLDKTNPQHYHYLIKGNCPRVSSISDKNGWKVVRNALTIIGFEDEE 283

  Fly   519 SNSIFRVIAVVLKLGNFIFVPITNIDGTEG-CQVSNVYEVQETAQLLNMEAQILINCLTRANSTN 582
            ..::..::|.||.|||..|.     :..|| ..::...::|..:|||.::..:|...||......
Zfish   284 IQALMEIVASVLHLGNTQFG-----EDEEGETHITTEAQLQFLSQLLGVDGSVLKAALTHKKIVA 343

  Fly   583 SAQEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLK-------STQREKNLALLDFYG 640
            ..:|.:. .:...||.:.|::..:.:|.|.|||||.|:|.||.       |::....:.|||.||
Zfish   344 KGEEMIS-PLSLEQALSARDSFAKAIYGRAFTWLVQKLNRSLAFKDEIYYSSKCSSVIGLLDIYG 407

  Fly   641 FEALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYG 705
            ||...|||||||.|||..||:.|.|:...|:||||.|..||:.|.|::||:|:.||:|:::...|
Zfish   408 FEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGVVWERVEYFNNKIICDLVEEKHKG 472

  Fly   706 ILSLINEPHLNSNDA----LLLRVQQCCAGHPNFMTTGSNSMC------------FQIRHYASVV 754
            |:::::|..|...||    .|.:::....||.:|:|   :.|.            |::.|||..|
Zfish   473 IIAILDEECLRRGDASDITFLEKLEDTLGGHAHFIT---HKMANGKIRKAIGREEFRLVHYAGEV 534

  Fly   755 NYSIHRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEGNPRRQVTKKPSTLSSNIRTQLQTLLAI 819
            ||:::.||:||:|:|.:::.....||...:|...|.......|  ::|.|.::..:..|..|:.|
Zfish   535 NYNVNGFLDKNNDLLYRHLKEVLCQSTNHIVSQCFHADELMDQ--RRPETAATQFKLSLAKLMDI 597

  Fly   820 VKHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLN 884
            :..:...||.|||||:||||.:||..||:|||:|:.||..:.:.|.|..|...:..|..|||.|.
Zfish   598 LMSKEPSYVRCIKPNDGKQPGRFDEVLVRHQVKYLGLMENLRVRRAGFAYRRSYEAFLERYKSLC 662

  Fly   885 SLTWPHFHGGSQVEGIALIIRNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQT 949
            ..|||::| |:..||:|.::::|.....||.:|...:|:|.|||::..|.....:...:||.:|.
Zfish   663 PDTWPNWH-GNLPEGVATLVKHLNYKPEEFKLGRSKIFIRFPRTLFITEDALEAQKQTIAVTLQK 726

  Fly   950 MFRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKRQVRW 1014
            .:|.|..|..:.|:||:.::|.|.||       |:  .||              |..|::||
Zfish   727 SWRGYRERANYHRIRHAVIVIQSWWR-------GV--KGR--------------RKAKHRRQ--- 765

  Fly  1015 AIDIIGRYYRQWKIR-----------------QFLLTIPLRLPPNTLSPLSTEWPVAPAFLADAS 1062
            |.|.|..:.:.:.:|                 .||:.:...||.   |.|...||..|..|.:||
Zfish   766 AADTIRNFIKGFILRNEPRCPDNEYFLDHVRFSFLMKVKRNLPK---SVLDKSWPKPPPSLTEAS 827

  Fly  1063 RHLRSIYHRWKCYIYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFVGDYVRLRHNQ-Q 1126
            .|:..|..|.....|........|.::.:||.||.|||.:|..|.|||...||.  .||...: .
Zfish   828 EHIHRICIRNLVNDYCRRIQPEWRKQLEQKVVASGIFKGQKDGYSRSVPKLFVA--TRLEAEEIN 890

  Fly  1127 WKKICAETNDQYVVFADIINKIARSSGKFVPIL--LVLSTSSLLLLDQRTLQIKYRVPASEIYRM 1189
            .|.:....:|..|.:...:.|..|..  |.|.:  |:|:|||.:|:.:  .:||.|:....:..:
Zfish   891 LKVLQTLGSDNKVKYGIAVTKYDRHG--FRPRVRQLLLTTSSAVLVQE--AKIKQRIDYGALLGI 951

  Fly  1190 SLSPYLDDIAVFHVKASEFGRKKGDFVFQTGHVIEIVTKMFLVIQNATGKPPEIHISTEFEANFG 1254
            |:|...|...|.|:..:: .::|||.|.|..||||.|||:.::..       :||     ..|..
Zfish   952 SVSSLSDGFFVLHIPTAD-SKQKGDLVLQCDHVIEAVTKLAIMAD-------KIH-----NVNIS 1003

  Fly  1255 QQTVIFSFKYG--GMSDLAQGPP-KVTRKAN 1282
            |.::.|:...|  |:.|...|.. :|.:..|
Zfish  1004 QDSIRFAIARGKEGVIDFTSGSDLRVVKSKN 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	19..>118	CDD:277568	39/98 (40%)
		Motor_domain	403..924	CDD:277568	201/549 (37%)
		Myosin_TH1	1092..1267	CDD:283635	55/179 (31%)
myo1ca	XP_005165404.1	MYSc	25..714	CDD:214580	263/961 (27%)
		MYSc_Myo1	44..701	CDD:276829	250/932 (27%)
		IQ	739..761	CDD:197470	11/44 (25%)
		Myosin_TH1	857..1026	CDD:283635	58/187 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105718at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720