Protein Alignment Myo95E and myo1cb

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_073779253.1
• Gene: myo1cb / 566459
• ZFINID: ZDB-GENE-090429-3
• Length: 1069
• Species: Danio rerio
• Alignment Length: 1304
• Identity: 352/1304 - (26%)
• Similarity: 572/1304 - (43%)
• Gaps: 364/1304 - (27%)

  Fly     5 IGTWDSVLLEN-LSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIF 68
            :|..|.||||| .||.:||.|:.:|:|.:.||||||:.:|::|||..:..::..::..|.....:
Zfish    53 VGVQDFVLLENHTSEVAFIENLRKRFKENLIYTYIGSVLVSVNPYKDLEIYTKQHMERYRGVNFY 117

  Fly    69 QLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRK 133
            ::.||||.:.:.||:|::.:..|||:|::|||||||||..|.::.:
Zfish   118 EVSPHIYAVADNAYRSMRTERRDQCILISGESGAGKTEASKKVLQY------------------- 163

  Fly   134 QSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIER 198
                                                                             
Zfish   164 ----------------------------------------------------------------- 163

  Fly   199 QSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKY 263
                                                                            |
Zfish   164 ----------------------------------------------------------------Y 164

  Fly   264 AVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHST 328
            ||.     |....|.:.|:.:.|:                     :||.
Zfish   165 AVT-----CPASDHVQTVKDRLLQ---------------------SNPV---------------- 187

  Fly   329 ESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMR 393
                                                                             
Zfish   188 ----------------------------------------------------------------- 187

  Fly   394 ECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERN 458
                     |||.|||.||:|:||||:||..||:.||||.|:|.||.:|:|||:|:.....||||
Zfish   188 ---------LEAFGNAKTLRNDNSSRFGKYMDIQFDFKGAPVGGHILNYLLEKSRVVHQSNGERN 243

  Fly   459 FHIFYQLLLGADLQLLKSLKLYRNVEKYELLRNTTAME----EDRMNFHYTKRSLDVLGLSCEES 519
            |||||||:.|.:..||:.|.|.||.::|:.|......:    .||.::...:::|.|:|.:.:|.
Zfish   244 FHIFYQLIEGGEDDLLRRLGLERNAQQYQYLVKGNCPKVSSINDRNDWKTVRKALSVIGFTDDEV 308

  Fly   520 NSIFRVIAVVLKLGNFIFVPITNIDGTE---GCQVSNVYEVQETAQLLNMEAQILINCLTRANST 581
            ..:..:||.||.|||..:       |.|   ...::...:::..|:||.::..:|...||. ...
Zfish   309 EELLNIIASVLHLGNVQY-------GGEDSGSAYITTDTQIKYLARLLGVDGTVLKEALTH-KKI 365

  Fly   582 NSAQEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLK------STQREKNLALLDFYG 640
            .:..|::...::..|||:.|:.|.:.:|.|.|:|||||||:||.      |::....:.|||.||
Zfish   366 IAKGEELMSPLNQEQAASARDALSKAIYGRTFSWLVNKINDSLAFKDESFSSKNASVIGLLDIYG 430

  Fly   641 FEALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYG 705
            ||...:||||||.|||..||:.|.|:...|:||||.|..||:.|..:.||:|:.||:|:::...|
Zfish   431 FEVFQNNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGITWEPVQYFNNKIICDLVEEKFKG 495

  Fly   706 ILSLINEPHLNSNDA----LLLRVQQCCAGHPNFMT----TGSNSMC-----FQIRHYASVVNYS 757
            |:|:::|..|...||    .|.:::....||.:|:|    .|.....     |::.|||..|||:
Zfish   496 IISILDEECLRPGDASDITFLEKLENTVGGHAHFLTHKLADGKTRKVMGREEFRLIHYAGEVNYN 560

  Fly   758 IHRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEGNPRRQVT--KKPSTLSSNIRTQLQTLLAIV 820
            :..||:||:|:|.:.:......|:..::...|    .|.:::  |:|.|.::..:..|..|:.|:
Zfish   561 VKGFLDKNNDLLFRNLKQVMCMSENKILNQCF----DREELSDKKRPETAATQFKNSLAKLMEIL 621

  Fly   821 KHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNS 885
            ..:...||.|||||:.||..:||..|::|||:|:.||..:.:.|.|..|...:..|..|||.|..
Zfish   622 MSKEPSYVRCIKPNDAKQAGRFDEVLIRHQVKYLGLMENLRVRRAGFAYRRRYETFLQRYKSLCP 686

  Fly   886 LTWPHFHGGSQVEGIALIIRNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQTM 950
            .|||:: .|.||:|::.::::|.....|:.:|...:|:|.|:|::..|....:|...||..:|:.
Zfish   687 DTWPNW-DGRQVDGVSTLVKHLGYKPEEYKLGRTKIFIRFPKTLFATEDALEVRKHSLATQLQSS 750

  Fly   951 FRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKRQVRWA 1015
            ::.|..:.::|:||||.:.|.:.||       ||             :||   |:.|.:|:   |
Zfish   751 WKGYSQKTKYQKMRHSAVWIQAWWR-------GI-------------LAR---RAAKRRRE---A 789

  Fly  1016 IDIIGRYYRQWKIR-----------------QFLLTIPLRLPPNTLSPLSTEWPVAPAFLADASR 1063
            .|.|.|:.:.:..|                 .||:.:. |..|.|:  |...||..|..|.:||:
Zfish   790 ADTIRRFIKGFIYRHQPRCPENEYFLDYVRYSFLMNLH-RCQPKTV--LDKSWPTPPPALVEASQ 851

  Fly  1064 HLRSIYHRWKCYIYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFVGDYVRLRHNQQWK 1128
            |||.:..:.....|..:.:...:::|.:||.||.||||:|.:|.:||...||.  .||.......
Zfish   852 HLRKLCMQNMVRKYCKNINPEWKHQMEQKVVASKIFKDKKDNYPQSVPKLFVN--TRLNGEDINP 914

  Fly  1129 KICAETNDQYVVFADIINKIARSSGKFVPILLVLSTSSLLLLDQRTLQIKYRVPASEIYRMSLSP 1193
            |:.....::.:.:|..:.|..|...|.....|:|.:.|.:::::.  ::|.|:..:.:..:|:|.
Zfish   915 KVLQALGNEKMKYAVPVIKYDRKGYKARNRQLLLMSDSAVIVEEG--KLKQRIDYNSLKGISVSS 977

  Fly  1194 YLDDIAVFHVKASEFGRKKGDFVFQTGHVIEIVTKMFLVIQNATGKPPEIHI---STEFEANFGQ 1255
            ..|.:.|||| |||..::|||.|.|..||||.:||:.:    ...|..:|:|   |.:|:...|:
Zfish   978 LSDGMFVFHV-ASEDNKQKGDVVLQNEHVIETLTKVAI----CADKMDDININQGSIKFDVAQGK 1037

  Fly  1256 QTVI 1259
            :.:|
Zfish  1038 EGII 1041

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	46/118 (39%)
		Motor_domain	<403..937	CDD:473979	201/561 (36%)
		Myosin_TH1	1092..1288	CDD:461801	54/171 (32%)
myo1cb	XP_073779253.1	None