Protein Alignment Myo95E and myo1a

DIOPT Version :9

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001008063.1
• Gene: myo1a / 493425
• XenbaseID: XB-GENE-979281
• Length: 1073
• Species: Xenopus tropicalis
• Alignment Length: 1343
• Identity: 382/1343 - (28%)
• Similarity: 610/1343 - (45%)
• Gaps: 332/1343 - (24%)

  Fly     1 MEQEIGTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDK 65
            |:..:|..|.:|||:|||:|.:.|:.:|:|.|.||||||..|:::|||..:..:|.:.|..|.:.
 Frog     8 MDGMVGVGDMILLESLSEESLLVNLKERFKSDEIYTYIGNVVISVNPYKSLPIYSPEKVEEYRNC 72

  Fly    66 GIFQLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNV 130
            .::||.||||.:.:.|||||:|:..|||:|:||||||||||..|::::::..:
 Frog    73 NLYQLKPHIYAVADDAYQSLRDRDRDQCILITGESGAGKTEASKLVMSYVAAV------------ 125

  Fly   131 LRKQSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAES 195
                                                                             
 Frog   126 ----------------------------------------------------------------- 125

  Fly   196 IERQSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGS 260
                                                                             
 Frog   126 ----------------------------------------------------------------- 125

  Fly   261 PKYAVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQ 325
                          ||                                       :|:..|.:::
 Frog   126 --------------CG---------------------------------------KGTEVNQVKE 137

  Fly   326 HSTESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQ 390
            ...:|.|
 Frog   138 QLLQSNP---------------------------------------------------------- 144

  Fly   391 RMRECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIG 455
                       .|||.|||.|::|:||||:||..|||.||||||||..|::|:|||:|:...:.|
 Frog   145 -----------VLEAFGNAKTIRNDNSSRFGKYMDIEFDFKGDPMGGVISNYLLEKSRVVKNVKG 198

  Fly   456 ERNFHIFYQLLLGADLQLLKSLKLYRNVEKYELLRNTTAMEE---DRMNFHYTKRSLDVLGLSCE 517
            |||||||||||.|...:||..|||..:..||..|.|..:...   |..||...|.:::::|||..
 Frog   199 ERNFHIFYQLLAGGGTELLGKLKLVPDCSKYNYLNNDPSSLNGMGDNENFQIVKNAMEIIGLSDA 263

  Fly   518 ESNSIFRVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANSTN 582
            |..||..::||:|||||.........:|...|.:::...::|...|:.:::.:|.|..: ..:..
 Frog   264 EVTSILEIVAVILKLGNVEIKGQFQANGMAACYITDTKGIKEIGALIGLDSSMLENAFS-VRTVE 327

  Fly   583 SAQEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKST--QREKNLALLDFYGFEALD 645
            :.||.|...::..|....|:.|.:.||.|||:|||.:||||:|.:  |..|.:.:||.||||.|:
 Frog   328 AKQEKVVTTLNQSQGIYARDALAKNLYDRLFSWLVQRINESIKVSEFQGRKVMGVLDIYGFEILE 392

  Fly   646 HNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYGILSLI 710
            .||||||.|||..||:.|.|:...|:.|||.|.|||::|:||.|.|||.||.||:..:.|||:::
 Frog   393 VNSFEQFIINYCNEKLQQIFIQMTLKEEQEEYTREGIKWTRIVYTDNEVICTLIEDNTNGILAVL 457

  Fly   711 NE----PHLNSNDALLLRVQQCCAGHPNF-------------MTTGSNSMCFQIRHYASVVNYSI 758
            :|    |...|:...|.::......|.:|             :|...|  ||:|.|||..|.|:.
 Frog   458 DEECLRPGKVSDATFLAKLGTKFKNHKHFQSKVTQNDKRIADLTLPDN--CFRIEHYAGQVTYNT 520

  Fly   759 HRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEGNPRRQVTKKPSTLSSNIRTQLQTLLAIVKHR 823
            ..||:||:|:|.:.:|.|.:.:|..|:::|||||:|:....|:|.|:....|..:.||:..:..:
 Frog   521 DGFLDKNNDLLFRDLSQAMWNAKHQLLKTLFPEGDPKNSSLKRPPTVGFQFRNSVSTLMKNLYAK 585

  Fly   824 RSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNSLTW 888
            ..:|:.|:|||..|:|..||..||:.|:.|:.|:..|.:.|.|..|..|:..|..|||:::..||
 Frog   586 NPNYIRCLKPNSSKKPSLFDDVLVKTQILYLGLLENVKVRRAGFAYRQLYKPFLERYKMISKKTW 650

  Fly   889 PHFHGGSQVEGIALIIRNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQTMFRM 953
            |.:.|.:: :|:|.::..|.:|..|..:|...:|:|:|.|:::||..||.|:.|||.||||:||.
 Frog   651 PQWAGEAR-DGVAAMMAELGIPDEEAALGHTKIFIRTPSTLFDLEDRRRRRLDELATLIQTLFRG 714

  Fly   954 YHARKRFQRMRHSQMIISSAWR------TWRECRF-GIPFTGRRHLWSLYRVAREEYRSLKYKRQ 1011
            :..|..|..||.||::||:.:|      .:::.:| .:........|.    ||...|..|..::
 Frog   715 WRCRTHFLLMRKSQIVISAFYRGHAQKKEYQKIKFSALLLQAYVRGWK----ARVLLRKFKLDKR 775

  Fly  1012 VRWAIDIIGRYYRQWKIRQ-------------------------FLLTIPLRLPPNTLSPLSTEW 1051
            ...|...|..|:|.:|:|:                         :.|.:...:|  ::||.:..|
 Frog   776 KESASSTICAYWRGYKVRKEFRKRFKSTASKKLANFIYLRILQMYFLGLKKNVP--SMSPTNKTW 838

  Fly  1052 -PVAPAFLADASRHLRSIYHRWKCYIYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFV 1115
             |....|||.||:.:..|:|.|||..:|.:.....:..:::|:.||.:|..:|..|..||..||.
 Frog   839 APPKYKFLAPASQEIMRIFHHWKCKKFRENLTPQKKAILQDKLCASELFNGKKKCYPASVAKPFQ 903

  Fly  1116 GDYVRLRHNQQWKKICAETNDQYVVFADIINKIARSSGKFVPILLVLSTSSLLLLDQRTLQIKYR 1180
            ||||.::.|.:.:|..:..:.:.:|.|: :.:|.:::||..|:||:|:.:.|.|:..:. |:|..
 Frog   904 GDYVGIQKNPKLQKGASGVSGKLLVAAN-VERITKTNGKGSPMLLLLTNTHLGLMTTKG-QVKSL 966

  Fly  1181 VPASEIYRMSLSPYLDDIAVFHVKASEFGRKKGDFVFQTGHVIEIVTKMFLVIQNATGKPPEIHI 1245
            ....||..:|:|.:.|.|.|..:..:.....||||:..:.:.|||::|::..:..||.....:.|
 Frog   967 AKLDEIASVSVSKFNDGIFVIQLTPTATAGLKGDFLLSSLNTIEILSKLYQSVLEATKNKLNVKI 1031

  Fly  1246 STEFEANFGQQTVIFSFKYGGMSDLAQGPPKVTRKANRMEIIV 1288
            |.||...|.:..:...|....:.: .:||....:.:..:|:.|
 Frog  1032 SDEFSVKFKKDPIALKFIEASVQN-GKGPVYKKKSSQTVEVFV 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	19..>118	CDD:277568	45/98 (46%)
		Motor_domain	403..924	CDD:277568	211/542 (39%)
		Myosin_TH1	1092..1267	CDD:283635	52/174 (30%)
myo1a	NP_001008063.1	MYSc_Myo1	31..685	CDD:276829	261/921 (28%)
		Myosin_TH1	880..1073	CDD:399188	55/195 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I8358
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105718at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13140
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.110