Protein Alignment Myo95E and Myo1d

DIOPT Version :9

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_036012676.1
• Gene: Myo1d / 338367
• MGIID: 107728
• Length: 1010
• Species: Mus musculus
• Alignment Length: 1224
• Identity: 293/1224 - (23%)
• Similarity: 498/1224 - (40%)
• Gaps: 380/1224 - (31%)

  Fly    28 RYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIFQLPPHIYGLTNLAYQSLKDQSEDQ 92
            |:::..|||:||..||::|||..::.:..|.|..|..:.:::.|||::.:.:.||:::|.:|:|.
Mouse    36 RFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDT 100

  Fly    93 CVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRKQSSTSSASGLVMHAHRRASSSCSG 157
            |::::|||||||||..|.|:.::..|.:
Mouse   101 CIMISGESGAGKTEASKYIMQYIAAITN------------------------------------- 128

  Fly   158 TANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIERQSRRHMREKIVDFDFSHHKSSENI 222
                                       ||||:
Mouse   129 ---------------------------PSQRA--------------------------------- 133

  Fly   223 SGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKYAVPTVYGGCRQCGHSKCVRAQSLE 287
                                                                             
Mouse   134 ----------------------------------------------------------------- 133

  Fly   288 KEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHSTESQPERERDRSSLMGSTQRISLYD 352
                                                         |.||.::.|:.|
Mouse   134 ---------------------------------------------EIERVKNMLLKS-------- 145

  Fly   353 AHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMRECVTCADVFLEAMGNACTLKNNNS 417
                                                     .||      |||.|||.|.:|:||
Mouse   146 -----------------------------------------NCV------LEAFGNAKTNRNDNS 163

  Fly   418 SRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERNFHIFYQLLLGADLQLLKSLKLYRN 482
            ||:||..||..||||||:|.||.:|:|||:|:.....|||:||.|||||.|...|:|.||.|.::
Mouse   164 SRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKS 228

  Fly   483 VEKYELLRNTTAME---EDRMNFHYTKRSLDVLGLSCEESNSIFRVIAVVLKLGNFIFVPITNID 544
            :..|..:|....::   .|...|.....::.|:|...||..::::::||:|.|||..|:    :|
Mouse   229 LSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFI----VD 289

  Fly   545 GTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANSTNSAQEDVGCEMDARQAATNRNTLCRTLY 609
            | :...:.|...|...|:||:.:|.::...|. ..:..:.::.:..:...::|:..|:...:.:|
Mouse   290 G-DTPLIENGKVVSVIAELLSTKADMVEKALL-YRTVATGRDIIDKQHTEQEASYGRDAFAKAIY 352

  Fly   610 SRLFTWLVNKINESLK-----STQREKN--LALLDFYGFEALDHNSFEQFAINYSAEKIHQNFVF 667
            .|||.|:|.:||:.::     :|...||  :.:||.||||..|:||||||.|||..||:.|.|:.
Mouse   353 ERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQ 417

  Fly   668 HVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYGILSLINEPHLN---SNDALLLRVQQCC 729
            .||:.|||.|.|||:.|..||||:|:.|.:|:::...||::::::..:|   ..|.:.|......
Mouse   418 LVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSK 482

  Fly   730 AG-HPNFMTTGSNSMC-----------FQIRHYASVVNYSIHRFLEKNSDMLPKYISAAFYQSKL 782
            .| |.:|   .|...|           |:|||||..|.||...|::||.|.|.:......|.|..
Mouse   483 LGKHGHF---SSRKTCASDKILEFDRDFRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNSSN 544

  Fly   783 SLVQSLFPEGN-PRRQVTKKPSTLSSNIRTQLQTLLAIVKHRRSHYVFCIKPNEGKQPHQFDMAL 846
            .::::::|||. ...:|||:|.|.::..:..:..|:..:..:..:||.|||||:.|.|..||...
Mouse   545 PVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDER 609

  Fly   847 VQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNSLTWPHFHGGSQVEGIALIIRNLPLPS 911
            .:|||.|:.|:..|.:.|.|..:...:.||.||||:::..|||:....|..|.:..:|.......
Mouse   610 CRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQD 674

  Fly   912 AEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQTMFRMYHARKRFQRMRHSQMIISSAWRT 976
             :...|...:|:|:|||::.||:.|...:..:.:.:|.::|...||.|::|.:.:..||
Mouse   675 -DVAYGKSKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTII------ 732

  Fly   977 WRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKRQVRWAIDIIGRYYRQWKIRQFLLTIPLRLPP 1041
                                                        ||||::|::.::..:..|.
Mouse   733 --------------------------------------------RYYRRYKVKSYIHEVARRF-- 751

  Fly  1042 NTLSPL-----STEWPVAPAFLADASRHLRSIYHRWKCYIYRNSFDQTARNRMREKVTASIIFKD 1101
            :.:..:     ..:||..|..|......|:||::||:......:...:...::|.||.|..:.|.
Mouse   752 HGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKG 816

  Fly  1102 RKASYGRSVGHPFVGDYVRLR-------------HNQQWKKICAETNDQY--VVFADIINKIARS 1151
            ::|..|  :...:.|:|:..:             .|:..:|      |:|  |:|:..:.|:.|.
Mouse   817 QRADLG--LQRAWEGNYLASKPDTPQTSGTFVPVANELKRK------DKYMNVLFSCHVRKVNRF 873

  Fly  1152 SGKFVPILLVLSTSSLLLLD-QRTLQIKYRVPASEIYRMSLSPYLDDIAVFHVK 1204
            | |.....:.::...|..:| .:..::...:|...:..:|:|...|.:.|||.|
Mouse   874 S-KVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTK 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	19..>118	CDD:277568	34/89 (38%)
		Motor_domain	403..924	CDD:277568	188/546 (34%)
		Myosin_TH1	1092..1267	CDD:283635	28/129 (22%)
Myo1d	XP_036012676.1	MYSc_Myo1	36..686	CDD:276829	234/921 (25%)
		Myosin_TH1	807..1000	CDD:399188	28/129 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122881at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.720