Protein Alignment Myo95E and Myo1g

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: NP_001423969.1
• Gene: Myo1g / 289785
• RGDID: 1306016
• Length: 1018
• Species: Rattus norvegicus
• Alignment Length: 1255
• Identity: 306/1255 - (24%)
• Similarity: 490/1255 - (39%)
• Gaps: 376/1255 - (29%)

  Fly     4 EIGTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIF 68
            |.|..|.|||:.|:.:.|:.|:..|:::..||||||..:|::|||..:..:..:.:..|..:.::
  Rat     8 EYGKPDFVLLDQLTMEEFMKNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIAKYQGRELY 72

  Fly    69 QLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRK 133
            :.|||:|.:.|.||:::|.:|.|.|::::|||||||||..|.|:.::
  Rat    73 ERPPHLYAVANAAYKAMKRRSRDTCIVISGESGAGKTEASKHIMQYI------------------ 119

  Fly   134 QSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIER 198
                                                                             
  Rat   120 ----------------------------------------------------------------- 119

  Fly   199 QSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKY 263
                                                                             
  Rat   120 ----------------------------------------------------------------- 119

  Fly   264 AVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHST 328
                                                      .|.|||:
  Rat   120 ------------------------------------------AAVTNPS---------------- 126

  Fly   329 ESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMR 393
             .:.|.||.:..|:.||
  Rat   127 -QRAEVERVKDVLLKST------------------------------------------------ 142

  Fly   394 ECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERN 458
             ||      |||.|||.|.:|:||||:||..||..||||||:|.||..|:|||:|:....:||||
  Rat   143 -CV------LEAFGNARTNRNHNSSRFGKYMDINFDFKGDPVGGHIHSYLLEKSRVLKQHVGERN 200

  Fly   459 FHIFYQLLLGADLQLLKSLKLYRNVEKYELLRN--------TTAMEEDRMNFHYTKRSLDVLGLS 515
            ||.|||||.|::.|.|:.|.|.||...|...|.        ..|:..|..:......::.::|.|
  Rat   201 FHAFYQLLRGSEDQELQELHLERNPAVYNFTRQGAGLNMGVHNALGSDEKSHQGVMEAMKIIGFS 265

  Fly   516 CEESNSIFRVIAVVLKLGNFIFVPITNIDGTE--GCQVSNVYEVQETAQLLNMEAQILINCLTRA 578
            .||..||.|::|.:|.|||..||. |..:|.:  |.:|::...|...|:|....:.:::..|...
  Rat   266 PEEVESIHRILAAILHLGNIEFVE-TEENGPQKGGLEVADEALVGYVAKLTATPSDLVLRTLLAR 329

  Fly   579 NSTNSAQEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKSTQREKN-------LALL 636
            ...:..:|.:.......:|:..|:...:.:|.|||.|:|||||..::...|:..       :.:|
  Rat   330 TVASGGREVIEKSHTVAEASYARDACAKAMYQRLFEWVVNKINSIMEPRDRDPRRDGKDTVIGVL 394

  Fly   637 DFYGFEALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDK 701
            |.||||....||||||.|||..||:.|.|:..:|:.|||.|.|||:.|..|:||:|.:|.||:::
  Rat   395 DIYGFEVFPVNSFEQFCINYCNEKLQQLFIQLILKQEQEEYEREGITWQSIEYFNNATIVELVEQ 459

  Fly   702 PSYGILSLINEPHLNS---NDALLLR-VQQCCAGHPNFMTTGSNSMC-----------FQIRHYA 751
            |..|||::::|....:   .|.:.|: :......||::   .|..:|           |||:|||
  Rat   460 PRRGILAVLDEACSTAGPITDRIFLQTLDTHHRHHPHY---SSRQLCPTDKTMEFGRDFQIKHYA 521

  Fly   752 SVVNYSIHRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEGNPR-RQVTKKPSTLSSNIRTQLQT 815
            ..|.||:..|::||.|.|.:......|.|....:::::|:|... .:|||:|.|..:..:..:..
  Rat   522 GDVTYSVEGFIDKNRDSLFQDFKRLLYNSMDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMIA 586

  Fly   816 LLAIVKHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRY 880
            |:..:..:...||.||||||.|.|.:.|.|..:|||.|:.|:..|.:.|.|......:.:|..||
  Rat   587 LVENLASKEPFYVRCIKPNEDKVPGRLDEAHCRHQVEYLGLLENVRVRRAGFASRQPYPRFLLRY 651

  Fly   881 KLLNSLTWPHFHGGSQVEGIALIIRNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAV 945
            |:....|||:...||..|.::.::....| ..:...|...:|:|||||:..|||.|...|..:.:
  Rat   652 KMTCEYTWPNHLLGSDREAVSALLEQHGL-QGDVAFGHSKLFIRSPRTLVTLEQSRAHLIPIIVL 715

  Fly   946 LIQTMFRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKR 1010
            |:|..:|...||.|.:|:|
  Rat   716 LLQKAWRGTLARWRCRRLR---------------------------------------------- 734

  Fly  1011 QVRWAIDIIGRYYRQWKIRQFLLTIPLRLPPNTLSPL---STEWPVAPAFLADASRHLRSIYHRW 1072
                ||..|..::|:.|:|..|:.:..|.......||   ...||..||.|.........::.||
  Rat   735 ----AIYTIMGWFRRHKVRAHLIELQRRFQAARQPPLYGRDLVWPTPPAVLQPFQDTCHILFSRW 795

  Fly  1073 KCYIYRNSFDQTARNRMREKVTASIIFKDRKASYG--RSVGHPFVG---DYVRLRH--NQQWKKI 1130
            :......:...:...:::.||.|....:..:..:|  |:....::.   |.....|  .:|.|.:
  Rat   796 RARQLVKNIPPSDMTQIKAKVAAMGALQGLRQDWGCQRAWARDYLSSDTDNPTASHLFAEQLKAL 860

  Fly  1131 CAETNDQYVVFADIINKIARSSGKFVPILLVLSTSSLLLLDQRTLQI----KYR----VPASEIY 1187
            ..:.....|:|:..:.|:.|...:        ...:|||.|:...::    :||    ||...:.
  Rat   861 REKDGFGTVLFSSHVRKVNRFRKR--------RDRALLLTDRHLYKLEPGRQYRVMRAVPLDAVT 917

  Fly  1188 RMSLSPYLDDIAVFHVKASE 1207
            .:|::...|.:.|.|.:..:
  Rat   918 GLSVTSGRDQLVVLHAQGHD 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	43/118 (36%)
		Motor_domain	<403..937	CDD:473979	199/566 (35%)
		Myosin_TH1	1092..1288	CDD:461801	25/131 (19%)
Myo1g	NP_001423969.1	None