Protein Alignment Myo95E and Myo31DF

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_061516868.1
• Gene: Myo31DF / 1279578
• VectorBaseID: AGAMI1_012998
• Length: 1025
• Species: Anopheles gambiae
• Alignment Length: 1326
• Identity: 323/1326 - (24%)
• Similarity: 545/1326 - (41%)
• Gaps: 397/1326 - (29%)

  Fly     3 QEIGTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGI 67
            ||:|..|.|||:.:::|.|::|:.:|::...||||||...:::|||..::.:..:.|..|..:.:
Mosquito     7 QEVGVQDFVLLDAVTQDKFMDNLKRRFQAGKIYTYIGEVCISVNPYREMNIYGPEYVNRYKGREL 71

  Fly    68 FQLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLR 132
            |:..|||:.:.:.||:.||.::.|.|::::|||||||||..|:|:.::
Mosquito    72 FENAPHIFAIADAAYRVLKQRNNDTCIMISGESGAGKTEASKIIMKYI----------------- 119

  Fly   133 KQSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIE 197
                                                                             
Mosquito   120 ----------------------------------------------------------------- 119

  Fly   198 RQSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPK 262
                                                                             
Mosquito   120 ----------------------------------------------------------------- 119

  Fly   263 YAVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHS 327
                                                       .|.||..
Mosquito   120 -------------------------------------------AAVTNQG--------------- 126

  Fly   328 TESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRM 392
              .|.|.||.::.|:.|
Mosquito   127 --KQGEIERVKNVLIKS------------------------------------------------ 141

  Fly   393 RECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGER 457
                   :..||..|||.|.:|:||||:||..|||.|:||||:|..||:|:|||:|:.....|||
Mosquito   142 -------NAILECFGNAKTNRNDNSSRFGKYMDIEFDYKGDPVGGIITNYLLEKSRVIQQQSGER 199

  Fly   458 NFHIFYQLLLGADLQLLKSLKLYRNVEKYELL-RNTTAMEEDRMNFHYTKRSLDVLGLSCEESNS 521
            |||.|||||.|.....|:...|.|:...|... :.:|.:..::.::..|...|..||.|.||.:.
Mosquito   200 NFHCFYQLLRGGANNELQQYNLVRDPAAYHYTNQGSTEILSEKSDYRATTGGLQALGFSAEEISM 264

  Fly   522 IFRVIAVVLKLGNFIF------VPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANS 580
            ::|.:|.:|.|||..|      :.|.|     |..::||      ||||.:.|:.:...||  ..
Mosquito   265 VWRTVAAILHLGNIEFKMKDEKITIAN-----GKTLANV------AQLLQVTAEEMRAALT--ER 316

  Fly   581 TNSAQEDVGCEM-DARQAATNRNTLCRTLYSRLFTWLVNKINESL----KSTQREKN--LALLDF 638
            ..:|:.::..:. |.:||...|:.|.:.:|.|:|||::.:||:::    .:||:..|  :.:||.
Mosquito   317 VIAARGEIMTKSHDTKQAEYGRDALAKAIYDRMFTWIIQRINKAIVVPGSTTQKRYNKVIGVLDI 381

  Fly   639 YGFEALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPS 703
            ||||..|.||||||.|||..||:.|.|:..||:.|||.|.|||:||:.|:||:|:.||.|:::..
Mosquito   382 YGFEIFDRNSFEQFCINYCNEKLQQLFIELVLKQEQEEYNREGIEWTNIEYFNNQIICALVEQAD 446

  Fly   704 YGILSLINEPHLN----SNDALLLRVQQCCAGHPNFMTTGSNSM--------CFQIRHYASVVNY 756
            .|:::::||..||    :::.||..:.:..:.||::.:.....|        .|:|.|||..|.|
Mosquito   447 KGVIAIMNEACLNVGKITDEMLLGDMDKKLSHHPHYSSRQLKPMDKELRHKEDFRITHYAGDVIY 511

  Fly   757 SIHRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEG-NPRRQVTKKPSTLSSNIRTQLQTLLAIV 820
            ||..|:|||.|.|.:......|.|...::.|::||| ....:.||:|.|..:..:..:..|:|.:
Mosquito   512 SISGFIEKNRDTLFQDFKRLLYGSHDKVISSMWPEGAQDIAKTTKRPLTAGTLFQKSMAELVATL 576

  Fly   821 KHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKLLNS 885
            ..:...||.|:|||:.|.|..||...|:|||||:.|:..|.:.|.|..:...:.||..|||:::.
Mosquito   577 LRKEPLYVRCVKPNDIKSPTVFDDVRVEHQVRYLGLLENVRVRRAGFVHRQRYDKFLLRYKMISQ 641

  Fly   886 LTWPHFHGGSQVEGIALII--RNLPLPSAEFTIGTKNVFVRSPRTVYELEQFRRLRISELAVLIQ 948
            .|||:|.||:..:|:.:::  :|.   ..:...|...:|:|||:|::.|||.|...|..:..|:|
Mosquito   642 YTWPNFRGGNDRDGVKVLMNEKNF---GHDVRFGKTKIFIRSPQTLFALEQQRNDMIPHIVTLLQ 703

  Fly   949 TMFRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYRSLKYKRQVR 1013
            ...|                    .|                       :||::|:.:|
Mosquito   704 KQVR--------------------GW-----------------------IARQKYKKMK------ 719

  Fly  1014 WAIDIIGRYYRQWKIRQFLLTIPLRL-PPNTLSPL--STEWPVAPAFLADASRHLRSIYHRWKCY 1075
             |..:|.|:||::|::.::..:.:|. ...||...  ..:||..|.....|.|.||.:|.||:..
Mosquito   720 -AALVIMRHYRKYKLKSYVQDLAVRFRNARTLRDYGKGIQWPQPPLVGRQAERQLRMLYSRWRAA 783

  Fly  1076 IYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFVGDYVRL--------RHNQQWKKICA 1132
            :....:.:....::|.::.|:..|:.|:..:|..  ..::|:|:.:        .:|...:.|..
Mosquito   784 MILRKYPREEWPQLRLQIIAASAFRKRRKCWGHD--RRWLGNYLSIVAENSNYSSYNASVRNIKN 846

  Fly  1133 ETNDQYVVFADIINKIARSSGKFVPILLVLSTSSLLLLD---QRTLQIKYRVPASEIYRMSLSPY 1194
            ..|...:||:..:.|..:.: |.....::::..::..||   .:...:|..|...||..:|:||.
Mosquito   847 VDNFDTIVFSAFVKKFNKCN-KSADRAIIVTDGTIYKLDGPKNKFRNMKRTVAIREITSISVSPG 910

  Fly  1195 LDDIAVFHVKASEFGRKKGDFV--FQTGH-----------VIEIVTKMFLVIQNATGKPPEIHIS 1246
            .|.:||||      .....|.:  .|..|           |..::.:.|.:.|...    .::::
Mosquito   911 RDQLAVFH------SHHNNDLIVSLQGEHQPLKEDRIGELVAHVIRRYFAICQQEL----PVNVA 965

  Fly  1247 TEFEANFGQQTVIFSFKYGGMSDLAQ 1272
            :......|.::...|.:.....|:.:
Mosquito   966 STIPLRLGNKSRSLSIEAAAGQDMPE 991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	43/119 (36%)
		Motor_domain	<403..937	CDD:473979	205/562 (36%)
		Myosin_TH1	1092..1288	CDD:461801	36/205 (18%)
Myo31DF	XP_061516868.1	None