Protein Alignment Myo95E and Myo10A

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_061508751.1
• Gene: Myo10A / 1274922
• VectorBaseID: AGAMI1_013284
• Length: 3076
• Species: Anopheles gambiae
• Alignment Length: 1043
• Identity: 260/1043 - (24%)
• Similarity: 396/1043 - (37%)
• Gaps: 326/1043 - (31%)

  Fly     6 GTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISE-HSLDNVRNYGDKGIFQ 69
            |..|...||:|.|.|.:.|:..||....|||..|:.::|:|||....| :.::..:.|..:.:..
Mosquito    99 GVEDMTQLEDLHEASLLWNLKLRYDNGLIYTNAGSILIAINPYKMFPESYGIEMAKLYSGRPLGT 163

  Fly    70 LPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRKQ 134
            ||||::.:.:.|:.:|   ...|.|:::||||:||||:.|:::.:|..:
Mosquito   164 LPPHLFAIGSAAHAAL---PSPQVVVISGESGSGKTESTKLVMQYLAAV---------------- 209

  Fly   135 SSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIERQ 199
                                                                             
Mosquito   210 ----------------------------------------------------------------- 209

  Fly   200 SRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKYA 264
                                                                             
Mosquito   210 ----------------------------------------------------------------- 209

  Fly   265 VPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHSTE 329
            ||   ||                                             ||.|.::.:...|
Mosquito   210 VP---GG---------------------------------------------GSASTVITEQILE 226

  Fly   330 SQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMRE 394
            :.|
Mosquito   227 AAP-------------------------------------------------------------- 229

  Fly   395 CVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFK-GDPMGVHITHYMLEKTRITDPIIGERN 458
                   .|||.|||.|::|:||||:||.  :|:.|| |..:|..||.|:|||:||.....||||
Mosquito   230 -------LLEAFGNARTVRNDNSSRFGKY--LEVYFKSGAIIGAKITQYLLEKSRIVTQAAGERN 285

  Fly   459 FHIFYQLLLG-ADLQLLKSLKLYRNVEKYELL-RNTTAMEEDRMNFHYTKRSLDVLGLSCEESNS 521
            :|:||:||.| |:.:.:|...|  ..:||..| :..:.....||::...:.::.|||::..|...
Mosquito   286 YHVFYELLGGLAEPERMKYGLL--EADKYFYLNQGGSDCAPGRMDWASLQSAMQVLGVTESEREG 348

  Fly   522 IFRVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLTRANSTNSAQE 586
            |.:|:|.||.|||..|.......|.||.::.:..|::..|.||.:.::.::..|| :..|.:..|
Mosquito   349 IVKVLASVLHLGNVYFHRRQLRHGQEGVEIGSDAEIKWAAHLLQLPSEGILKSLT-SRITETRSE 412

  Fly   587 DVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLK--STQREKNLALLDFYGFEALDHNSF 649
            .:...:...||...|:.|.:.|||.||.|||.:||..:.  .|...:.|::||.:|||.|..|||
Mosquito   413 RLYTPLGIDQALDARDALAKALYSGLFNWLVLRINSIVHRGGTHDAQRLSILDIFGFEDLAENSF 477

  Fly   650 EQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYGILSLI---- 710
            ||..|||:.|.:...|..||.:.||..|.||.|||:.:::.||..:..|:.|...||..|:
Mosquito   478 EQLCINYANESLQLYFNKHVFKLEQAEYARERLEWTNLEWEDNLPVIHLLAKKPVGIFHLLDDES 542

  Fly   711 NEPHLNSNDALLLRVQQCCAGH--------PNFMTTGSNSMCFQIRHYASVVNYSIHRFLEKNSD 767
            |.|..|.:..|    ::|...|        |.   .|:..  |.|.|||..|.|.:..|||||.|
Mosquito   543 NFPRANDSSFL----EKCHYNHALNELYSRPR---VGAQE--FGITHYAGQVWYCVDGFLEKNRD 598

  Fly   768 MLPKYISAAFYQSKLSLVQSL-------------FPEGNPRRQVTKKP--STLSSNIRTQLQTLL 817
            .|...:......|...||..:             .|:|:..|.||.||  .|:::.....||.||
Mosquito   599 ALRMDVIELLSSSTEPLVGEMTKQLRAQRDVGKTLPKGSNGRFVTMKPRTPTVAARFSDSLQQLL 663

  Fly   818 AIVKHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYKL 882
            ..:......:|.|:|||..||..:.||..|..|:||:.::..:.:.::|:...|....|..||:.
Mosquito   664 QSMAKCNPWFVRCVKPNNDKQALRMDMPCVLQQLRYLGMLDTIKIRQSGYPVRLRFQHFVERYRH 728

  Fly   883 LNSLTWPHFHGGSQVEGIALIIRNLPLPSAE---FTIGTKNVFVRSP--RTVYELEQFRRLRISE 942
            |.....|  .|....|....::..||..:.|   |.:|...||:|..  ||: |..:..|||::
Mosquito   729 LMRTPLP--KGTPYRELCRFVLDELPGTTTEGPDFQLGATRVFLREALHRTL-EASRADRLRLA- 789

  Fly   943 LAVLIQTMFRMYHARKRFQRMRHSQMIISSAWRTWRE-CRFGIPFTGRRHLWSLYR--VAREEYR 1004
             ||.||...|...|||:.||.....:.|...||.:|: .|:.....|.....:||:  :.|:.|.
Mosquito   790 -AVTIQRTVRGMLARKKVQREVRGAVTIQRYWRGYRDRNRYLTIKNGVVKYQALYKGHMQRKRYA 853

  Fly  1005 SLK 1007
            .||
Mosquito   854 KLK 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	38/117 (32%)
		Motor_domain	<403..937	CDD:473979	188/570 (33%)
		Myosin_TH1	1092..1288	CDD:461801
Myo10A	XP_061508751.1	None