Protein Alignment Myo95E and myo7ba

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_068078080.2
• Gene: myo7ba / 108190403
• ZFINID: ZDB-GENE-100914-4
• Length: 2220
• Species: Danio rerio
• Alignment Length: 1144
• Identity: 277/1144 - (24%)
• Similarity: 436/1144 - (38%)
• Gaps: 363/1144 - (31%)

  Fly     6 GTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYGDKGIFQL 70
            |..|.:.|.:|:|...:.|:..|||...||||.|:.:||:|||..:..::.:.|..|.|:.:..|
Zfish    60 GVDDMIRLGDLNEAGLLRNLLVRYKEGAIYTYTGSILVAVNPYQLLPIYTPEQVEQYTDRRLGDL 124

  Fly    71 PPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTPNVLRKQS 135
            |||::.:.:..:.:::...:|||.:::|||||||||:.|:::.||
Zfish   125 PPHVFAIADSCFFNMRRNRKDQCCIISGESGAGKTESTKLMLQFL-------------------- 169

  Fly   136 STSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRAESIERQS 200
              ::.||                                            |||
Zfish   170 --AAVSG--------------------------------------------QRS----------- 177

  Fly   201 RRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAKGSPKYAV 265
                                                                             
Zfish   178 ----------------------------------------------------------------- 177

  Fly   266 PTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLMRQHSTES 330
                          .:..|.||                     .||
Zfish   178 --------------WIEQQVLE---------------------ANP------------------- 188

  Fly   331 QPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSPTQRMREC 395
                                                                             
Zfish   189 ----------------------------------------------------------------- 188

  Fly   396 VTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPIIGERNFH 460
                  .|||.|||.|::|:||||:||..||..:..|...|..|..|:|||:|:......|||:|
Zfish   189 ------ILEAFGNAKTIRNDNSSRFGKYIDIHFNKSGAIEGARIEQYLLEKSRVCRQASQERNYH 247

  Fly   461 IFYQLLLGADLQLLKSLKLYRNVE-KYELLRNTTAME--EDRMNFHYTKRSLDVLGLSCEESNSI 522
            |||.:|:|......|.|.|....| .|..:...|:.|  :|...:...:.::.:|..:..::..|
Zfish   248 IFYCMLMGMPADQKKILSLGNAAEYNYLTMGKCTSCEGRDDIKEYASFRSAMKILTFTENDTWEI 312

  Fly   523 FRVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEAQILINCLT-RANSTNSAQE 586
            .:::|.:|.|||..|.. |.::..|||.:.:....:...|||.:....|...|| |:..||  :|
Zfish   313 NKLLASILHLGNVDFEE-TIMNNLEGCDILSSTHFKMATQLLEVAPNALDASLTQRSLMTN--RE 374

  Fly   587 DVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKSTQRE------KNLALLDFYGFEALD 645
            .|...:.:.||...|:...:.:|.|||.|:|.|||.::.....:      .::.|||.:|||...
Zfish   375 SVTKPLTSAQALDGRDAFVKAIYGRLFVWIVTKINSAIYKPPSDDPKHVRHSIGLLDIFGFENFK 439

  Fly   646 HNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKPSYGILSLI 710
            :|||||..||::.|::.|.||.||.:.||:.|.||.:.|..|::.||:|..:::...|..|||||
Zfish   440 NNSFEQLCINFANEQLQQFFVKHVFKLEQQEYAREDIVWKNIEFNDNQSTLDVLAIKSLNILSLI 504

  Fly   711 NEPHL--NSNDALLLRVQQCCAGHPNFMTTGSNS--MCFQIRHYASVVNYSIHRFLEKNSDMLPK 771
            :|...  ...||.:|.......|..:......|:  ..|.|||:|.||:|....|||||.|.|..
Zfish   505 DEESRFPKGTDATMLNKMNQHHGKGDIYMPPKNNHDTQFGIRHFAGVVHYDSKGFLEKNRDALSS 569

  Fly   772 YISAAFYQSKLSLVQSLF-------------------PEGNPRRQV-TKKP-STLSSNIRTQLQT 815
            .|....:.|...|::.:|                   |:.:.|:.. |||. .||:...|..|.:
Zfish   570 DIIQLIHTSSNKLLKQIFHSEISTIEGKTSINHTIVTPKSSLRQTADTKKQVPTLTGQFRQSLDS 634

  Fly   816 LLAIVKHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHV--KFFH 878
            |:..:...:..::.|||||:.|:|..||..|...|:||..:|..:.:.:.|  |.:.|.  :|..
Zfish   635 LMKTLTACQPFFIRCIKPNDFKKPMLFDRELCIRQLRYSGMMETIRIRKAG--YPIRHTFDEFLE 697

  Fly   879 RYKLL--NSLTWPHFHGGSQ-VEGIALIIRNLPLPSAEFTIGTKNVFVRS-PRTVYELEQFRRLR 939
            ||::|  :::..|......: .|.|..||    |...::.||...||::. ..||.||.:.:.|
Zfish   698 RYRVLLKSTVCDPQTETVKKCCESICKII----LTEDDWKIGKTKVFLKDFHDTVLELARDKAL- 757

  Fly   940 ISELAVLIQTMFRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLYRVAREEYR 1004
             :|.|:|||.:.|.|..||.|.|.|.:.:.|...||..:         ||:    ||||.:..|.
Zfish   758 -NEKALLIQKVLRGYKHRKAFLRKRGAAVTIQKTWRGHK---------GRK----LYRVVQLGYA 808

  Fly  1005 SLKYK---RQVRWAIDIIGRYYRQWKIRQFLLTIPLRLPPNTLSPLS-TEWPVAPAFLADASRHL 1065
            .|:.:   |::.|.       |:| |.:..||     |...|...|: .||           :..
Zfish   809 RLQAQVRSRKMAWE-------YKQ-KRKATLL-----LQSQTRGCLARKEW-----------KRK 849

  Fly  1066 RSIYHRWKCYIYRNSFDQTARNRMREKVTASIIFKDRKA 1104
            |......:.|. |.:..:.|.|:|:.....|:  ::|:|
Zfish   850 RDAVILLQAYT-RGTLARKAVNKMKRDAFLSL--QERRA 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	41/116 (35%)
		Motor_domain	<403..937	CDD:473979	181/574 (32%)
		Myosin_TH1	1092..1288	CDD:461801	3/13 (23%)
myo7ba	XP_068078080.2	None