Protein Alignment Myo95E and myo1d

DIOPT Version :10

• Sequence 1: NP_001027208.1
• Gene: Myo95E / 2768680
• FlyBaseID: FBgn0039157
• Length: 1288
• Species: Drosophila melanogaster
• Sequence 2: XP_002935562.1
• Gene: myo1d / 100497691
• XenbaseID: XB-GENE-5877220
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 1314
• Identity: 317/1314 - (24%)
• Similarity: 520/1314 - (39%)
• Gaps: 452/1314 - (34%)

  Fly     2 EQE---IGTWDSVLLENLSEDSFINNIHQRYKRDHIYTYIGTSVVALNPYHHISEHSLDNVRNYG 63
            |||   .|..|.||:::::...|:.|:..|:::..|||:||..||::|||.::..:..|.:..|.
 Frog     3 EQEGLQFGKADFVLMDSVTLPEFMENLKLRFEKGRIYTFIGEVVVSVNPYKNLPIYGRDTIEQYK 67

  Fly    64 DKGIFQLPPHIYGLTNLAYQSLKDQSEDQCVLLTGESGAGKTETFKMIVNFLTHIQDRSHCPPTP 128
            .:.:::.|||::.:.:.||:::|.:.:|.|::::|||||||||..|.|:.::..|.:
 Frog    68 GRELYERPPHLFSIADAAYKAMKRRCKDTCIVISGESGAGKTEASKYIMQYIAAITN-------- 124

  Fly   129 NVLRKQSSTSSASGLVMHAHRRASSSCSGTANFIICKNRAENPSGSVSRRQSPSPGPSQRSRTRA 193
                                                                    ||||:
 Frog   125 --------------------------------------------------------PSQRA---- 129

  Fly   194 ESIERQSRRHMREKIVDFDFSHHKSSENISGLPESHAHHMHPTKSCFKHQQTQVSACTAMPAAAK 258
                                                                             
 Frog   130 ----------------------------------------------------------------- 129

  Fly   259 GSPKYAVPTVYGGCRQCGHSKCVRAQSLEKEERDDLRGSNCRLSTIATATTNPAHPHRGSCSNLM 323
                                                                             
 Frog   130 ----------------------------------------------------------------- 129

  Fly   324 RQHSTESQPERERDRSSLMGSTQRISLYDAHKLSKVLGDLPPPPPSSVSPTPSASSSLHRRHKSP 388
                     |.||.::.|:.|
 Frog   130 ---------EVERVKNMLLKS-------------------------------------------- 141

  Fly   389 TQRMRECVTCADVFLEAMGNACTLKNNNSSRYGKLFDIEIDFKGDPMGVHITHYMLEKTRITDPI 453
                 .||      |||.|||.|.:|:||||:||..||..||||||:|.||::|:|||:|:....
 Frog   142 -----NCV------LEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHISNYLLEKSRVIVQQ 195

  Fly   454 IGERNFHIFYQLLLGADLQLLKSLKLYRNVEKYELLRNTTAME---EDRMNFHYTKRSLDVLGLS 515
            :||||||.|||::|||..|.|:||.|.:::..|...|:...::   .|..:|.....::.|:|..
 Frog   196 LGERNFHSFYQMILGAPEQTLRSLHLQKDISLYAYTRSLAQLKSSNNDTGDFKDVAEAMKVIGFK 260

  Fly   516 CEESNSIFRVIAVVLKLGNFIFVPITNIDGTEGCQVSNVYEVQETAQLLNMEA-QILINCLTRAN 579
            .||..::::::|.:|.|||..||    :|| :...:.|...:...|.||...: |:....|.|..
 Frog   261 PEEIQTVYKILAAILHLGNLKFV----LDG-DTTLIENGKVISVVADLLGTRSEQVEKALLFRTV 320

  Fly   580 STNSAQEDVGCEMDARQAATNRNTLCRTLYSRLFTWLVNKINESLKSTQRE-----KN--LALLD 637
            :|  .::.:..:...::|...|:...:.:|.|||.|:||:||:.:...|::     ||  :.:||
 Frog   321 AT--GRDVIDKQHTEKEANYGRDAFAKAIYERLFCWIVNRINDVIDVKQQDAALHGKNTVIGVLD 383

  Fly   638 FYGFEALDHNSFEQFAINYSAEKIHQNFVFHVLRSEQELYIREGLEWSRIDYFDNESICELIDKP 702
            .||||..|:||||||.|||..||:.|.|:..||..||..|.|||:.|..||||||:.|.:|:::.
 Frog   384 IYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLTQEQAEYQREGIPWKHIDYFDNQIIVDLVEQQ 448

  Fly   703 SYGILSLINEPHLN----SNDALLLRVQQCCAGHPNFMTTGSNSMC-----------FQIRHYAS 752
            ..||::|:::..:|    :::..|..:.:....|.::   .|..:|           |:|||||.
 Frog   449 HRGIIALLDDACMNVGKVTDNMFLEALDKQLGKHAHY---SSRKVCATDKALEYNRDFRIRHYAG 510

  Fly   753 VVNYSIHRFLEKNSDMLPKYISAAFYQSKLSLVQSLFPEGN-PRRQVTKKPSTLSSNIRTQLQTL 816
            .|.||:..|::||.|.|.:......:.|..:::::::|||. ...:|||:|.|.::..:..:..|
 Frog   511 DVVYSVVGFIDKNKDTLFQDFKRLMFNSSNAVLKAMWPEGKLSITEVTKRPLTAATLFKNSMIAL 575

  Fly   817 LAIVKHRRSHYVFCIKPNEGKQPHQFDMALVQHQVRYMSLMPLVHLCRTGHCYHLLHVKFFHRYK 881
            :..:..:..:||.||||||.|.|..||....:|||.|:.|:..|.:.|.|..|..::.||.||||
 Frog   576 VDNLASKEPYYVRCIKPNEKKSPALFDEVRCKHQVEYLGLLENVRVRRAGFAYRQVYEKFLHRYK 640

  Fly   882 LLNSLTWPHFHGGSQVEGIALIIRNLPLPSAEFTI---------------GTKNVFVRSPRTVYE 931
            |::|||||                |..|||....:               |...:|:|:|||::.
 Frog   641 LISSLTWP----------------NHSLPSDRIAVERFMVDCGLNHDAAYGKTKIFIRTPRTLFF 689

  Fly   932 LEQFRRLRISELAVLIQTMFRMYHARKRFQRMRHSQMIISSAWRTWRECRFGIPFTGRRHLWSLY 996
            ||:.|...:..:.:.:|.::|...||:|.:|:|....|:
 Frog   690 LEERRSEMLIRIILFLQKLWRGTLARRRCKRIRAGLTIL-------------------------- 728

  Fly   997 RVAREEYRSLKYKRQVRWAIDIIGRYYRQWKIRQFLLTIPLRLPPNTLS-----PLSTEWPVAPA 1056
                                    ||||::|::.:|..:..|.  |.:.     ....:||..|.
 Frog   729 ------------------------RYYRRYKVKSYLREVMHRF--NGVKNSRDYGKHVKWPTPPK 767

  Fly  1057 FLADASRHLRSIYHRWKCYIYRNSFDQTARNRMREKVTASIIFKDRKASYGRSVGHPFVGDYVRL 1121
            .|......|:.||:||:.|....|.......::|.||.|....|..:...|  :...:.|.|:.|
 Frog   768 VLRRFQEALQHIYNRWRGYQIIRSLPPAEIPKVRAKVAAFENLKGHRVDMG--LQRCWEGSYLAL 830

  Fly  1122 RHNQQWKKICAETNDQYVVFADIINKIARSS-----GKFVPILL---VLSTSSLLLLDQRTLQIK 1178
              ||:    ....:|.:|         :|||     .||:..|.   |...:....::.|.:.|.
 Frog   831 --NQE----NGRDSDLFV---------SRSSELQRKDKFMQALFSCHVRKVNRFNKVEDRAIFIT 880

  Fly  1179 ----YRVPASEIYRMSLSPYL------------DDIAVFHVKASEFGRKKGDFVFQTGHVIEIVT 1227
                |::...:.|::..|..|            |.:.|||.|.:
 Frog   881 DRHLYKMDPGKAYKVMTSTPLYNVSGISVTSGKDQLVVFHTKDN--------------------- 924

  Fly  1228 KMFLVIQNATGKPP 1241
            |..:|....:|:||
 Frog   925 KDLIVCLGCSGQPP 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo95E	NP_001027208.1	Motor_domain	3..>123	CDD:473979	41/122 (34%)
		Motor_domain	<403..937	CDD:473979	200/575 (35%)
		Myosin_TH1	1092..1288	CDD:461801	35/174 (20%)
myo1d	XP_002935562.1	MYSc_Myo1	24..682	CDD:276829	240/945 (25%)
		Myosin_TH1	803..1004	CDD:461801	35/174 (20%)