DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment p38c and zgc:171775

DIOPT Version :9

Sequence 1:	NP_996277.1	Gene:	p38c / 2768679	FlyBaseID:	FBgn0267339	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001104637.1	Gene:	zgc:171775 / 562552	ZFINID:	ZDB-GENE-030131-4309	Length:	359	Species:	Danio rerio

Alignment Length:	347	Identity:	147/347 - (42%)
Similarity:	221/347 - (63%)	Gaps:	3/347 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREI 68
            |.|:.|.::.|:.||.|..::.:|.|::|.|.....:.|:...|:|:|.|||:....||..|||:
Zfish     9 FHRLDIQKTTWDVPDRYTSLKPVGSGAYGTVCFAVDQKTKEKVAIKKLYRPFQSLIHAKRAYREL 73

  Fly    69 RLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILR 133
            |||:|:.|.|||.|||||.|.: ::.:|...|:|...:..||....:.|:::...|..:.|||||
Zfish    74 RLLRHIQHDNVICLLNVFTPDS-SLEKFDTFYMVMPFVAQDLGHIMKRKQLTSNVITYLFYQILR 137

  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYT 198
            |||||||||::||||||.|:||:.|.|::||||||:|....:||.:|.|.||.|||:||....||
Zfish   138 GLKYIHSAGIIHRDLKPNNLAVDENCELKILDFGLARHTETEMTGYVVTRWYRAPEVIFNWMHYT 202

  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQ 263
            :.:|||:.||||||:||..|||.|.:.:.|::.::|:.|||....:..:..:.:::|:...|:::
Zfish   203 QTVDVWTAGCILAEMITGEVLFPGSDSIDQLKKILNLTGTPNSTLVLKMQSKDAQSYVRSLPVQK 267

  Fly   264 RCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFEN 328
            :..|..:|.|.|..||||:|.||.:.||.|::|...:.||||.:..:|.:  |..:|.||.:||:
Zfish   268 KKAFKEVFSGMDPNAIDLLEGMLVLDPEVRLSAKNGLSHPYLSEFHDPEN--EPVSPPYDDSFES 330

  Fly   329 MVLPVKCWKELVSHEIRNFRPD 350
            |.|.|..||.|:..||..|.|:
Zfish   331 MDLAVSEWKSLIHMEIMTFDPN 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	146/344 (42%)
p38c	NP_996277.1	S_TKc	20..305	CDD:214567	122/284 (43%)
zgc:171775	NP_001104637.1	STKc_p38	9..351	CDD:143356	146/344 (42%)
zgc:171775	NP_001104637.1	S_TKc	25..309	CDD:214567	122/284 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575940
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850