DRSC/TRiP Functional Genomics Resources

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Protein Alignment p38c and MAPK13

DIOPT Version :9

Sequence 1:NP_996277.1 Gene:p38c / 2768679 FlyBaseID:FBgn0267339 Length:356 Species:Drosophila melanogaster
Sequence 2:NP_002745.1 Gene:MAPK13 / 5603 HGNCID:6875 Length:365 Species:Homo sapiens


Alignment Length:346 Identity:146/346 - (42%)
Similarity:216/346 - (62%) Gaps:3/346 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREI 68
            |.:..:|::.||.|..|.....:|.|::|.|.....:.:....|:|:|.|||:.|..||..|||:
Human     9 FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYREL 73

  Fly    69 RLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILR 133
            .|||||.|.|||.||:|| .||.::..|...|||...|..||.:. .....|:::|:.::||:|:
Human    74 LLLKHMQHENVIGLLDVF-TPASSLRNFYDFYLVMPFMQTDLQKI-MGMEFSEEKIQYLVYQMLK 136

  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYT 198
            |||||||||||||||||.|:|||.:.|::||||||:|....:||.:|.|.||.|||:|.....|.
Human   137 GLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHYN 201

  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQ 263
            :.:|:||||||:||::|.:.||:|::|:.|:..::.:.|.|..||:..::.:.:::|::..|...
Human   202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTP 266

  Fly   264 RCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFEN 328
            |.||..||.....||.||:|||||:..:||:|||:|:.||:.....:|....|...| :|.:.|:
Human   267 RKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQP-FDDSLEH 330

  Fly   329 MVLPVKCWKELVSHEIRNFRP 349
            ..|.|..||:.:..||.||.|
Human   331 EKLTVDEWKQHIYKEIVNFSP 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
p38cNP_996277.1 STKc_p38 4..349 CDD:143356 145/344 (42%)
S_TKc 20..305 CDD:214567 127/284 (45%)
MAPK13NP_002745.1 STKc_p38delta 9..351 CDD:143384 145/344 (42%)
TXY 180..182 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165143097
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0660
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D324618at33208
OrthoFinder 1 1.000 - - FOG0000533
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24055
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
65.850

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