Protein Alignment p38c and MAPK13

DIOPT Version :10

• Sequence 1: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 146/346 - (42%)
• Similarity: 216/346 - (62%)
• Gaps: 3/346 - (0%)

  Fly     4 FVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREI 68
            |.:..:|::.||.|..|.....:|.|::|.|.....:.:....|:|:|.|||:.|..||..|||:
Human     9 FYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYREL 73

  Fly    69 RLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILR 133
            .|||||.|.|||.||:|| .||.::..|...|||...|..||.:. .....|:::|:.::||:|:
Human    74 LLLKHMQHENVIGLLDVF-TPASSLRNFYDFYLVMPFMQTDLQKI-MGMEFSEEKIQYLVYQMLK 136

  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYT 198
            |||||||||||||||||.|:|||.:.|::||||||:|....:||.:|.|.||.|||:|.....|.
Human   137 GLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILSWMHYN 201

  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQ 263
            :.:|:||||||:||::|.:.||:|::|:.|:..::.:.|.|..||:..::.:.:::|::..|...
Human   202 QTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAKSYIQSLPQTP 266

  Fly   264 RCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFEN 328
            |.||..||.....||.||:|||||:..:||:|||:|:.||:.....:|....|...| :|.:.|:
Human   267 RKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQQP-FDDSLEH 330

  Fly   329 MVLPVKCWKELVSHEIRNFRP 349
            ..|.|..||:.:..||.||.|
Human   331 EKLTVDEWKQHIYKEIVNFSP 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	145/344 (42%)
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	145/344 (42%)
		TXY	180..182		1/1 (100%)