Protein Alignment p38c and MAPK7

DIOPT Version :10

• Sequence 1: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: XP_006721620.1
• Gene: MAPK7 / 5598
• HGNCID: 6880
• Length: 822
• Species: Homo sapiens
• Alignment Length: 344
• Identity: 135/344 - (39%)
• Similarity: 207/344 - (60%)
• Gaps: 16/344 - (4%)

  Fly    18 DIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISL 82
            |.||.:..:|.|::|.|:..|.|.|....|:|::...|:...:||.|.||:::|||..|.|:|::
Human    53 DEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAI 117

  Fly    83 LNVFHPPAHNMMEFQQV------YLVTHLMDADLHRYSRSKR-MSDQEIRIILYQILRGLKYIHS 140
            .::..|.. ...||:.|      |:|..||::|||:...|.: ::.:.:|..|||:||||||:||
Human   118 KDILRPTV-PYGEFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHS 181

  Fly   141 AGVVHRDLKPCNIAVNGNSEVRILDFGLSR-MCADK------MTDHVGTMWYLAPEIIFLRGQYT 198
            |.|:||||||.|:.||.|.|::|.|||::| :|...      ||::|.|.||.|||::....:||
Human   182 AQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT 246

  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQ 263
            :|||:||||||..|::..|.||.|:|||.|::.::.::|||:...|..:..||.|.|::..|.||
Human   247 QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQSLPPRQ 311

  Fly   264 RCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNFEN 328
            ...:..::.|.|.||:.|:.:||...|..||:||.|:.||:|....:|... .|.||.:|..|:.
Human   312 PVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDE-PDCAPPFDFAFDR 375

  Fly   329 MVLPVKCWKELVSHEIRNF 347
            ..|..:..||.:..||.:|
Human   376 EALTRERIKEAIVAEIEDF 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	135/344 (39%)
MAPK7	XP_006721620.1	STKc_ERK5	49..390	CDD:270842	132/338 (39%)