Protein Alignment p38c and MAPK3

DIOPT Version :10

• Sequence 1: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_002737.2
• Gene: MAPK3 / 5595
• HGNCID: 6877
• Length: 379
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 133/345 - (38%)
• Similarity: 208/345 - (60%)
• Gaps: 20/345 - (5%)

  Fly    20 YEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISLLN 84
            |..::::|.|::|.|:.......:...|:|:: .|||.:...:.|.|||::|....|.|||.:.:
Human    42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKI-SPFEHQTYCQRTLREIQILLRFRHENVIGIRD 105

  Fly    85 VFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILRGLKYIHSAGVVHRDLK 149
            :..  |..:...:.||:|..||:.||::..:|:::|:..|...||||||||||||||.|:|||||
Human   106 ILR--ASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLK 168

  Fly   150 PCNIAVNGNSEVRILDFGLSRMCADKMTDHVG-------TMWYLAPEIIFLRGQYTKAIDVWSVG 207
            |.|:.:|...:::|.||||:|: ||...||.|       |.||.||||:.....|||:||:||||
Human   169 PSNLLINTTCDLKICDFGLARI-ADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVG 232

  Fly   208 CILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQRCDFHHLFM 272
            |||||::::|.:|.|::|:.|:..::.|:|:|::|.:..|...::||||:..|.:.:..:..||.
Human   233 CILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFP 297

  Fly   273 GYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNF----ENMVLPV 333
            ..|.:|:||:::||...|.||||..||:.||||....:|     ...||.::.|    |...||.
Human   298 KSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDP-----TDEPVAEEPFTFAMELDDLPK 357

  Fly   334 KCWKELVSHEIRNFRPDQLD 353
            :..|||:..|...|:|..|:
Human   358 ERLKELIFQETARFQPGVLE 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	131/339 (39%)
MAPK3	NP_002737.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_ERK1_2_like	36..370	CDD:270839	130/336 (39%)
		TXY	202..204		0/1 (0%)