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Protein Alignment p38c and MAPK1

DIOPT Version :9

Sequence 1:	NP_996277.1	Gene:	p38c / 2768679	FlyBaseID:	FBgn0267339	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_002736.3	Gene:	MAPK1 / 5594	HGNCID:	6871	Length:	360	Species:	Homo sapiens

Alignment Length:	363	Identity:	135/363 - (37%)
Similarity:	214/363 - (58%)	Gaps:	32/363 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PEFVRVAINESLWEFPDIYEFVRFLGGGSFGQVA-------KVRLRGTENYFAMKRLMRPFEREE 59
            ||.||    ..:::....|..:.::|.|::|.|.       |||:       |:|:: .|||.:.
Human    11 PEMVR----GQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRV-------AIKKI-SPFEHQT 63

  Fly    60 DAKGTYREIRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEI 124
            ..:.|.|||::|....|.|:|.:.::...|....|  :.||:|..||:.||::..:::.:|:..|
Human    64 YCQRTLREIKILLRFRHENIIGINDIIRAPTIEQM--KDVYIVQDLMETDLYKLLKTQHLSNDHI 126

  Fly   125 RIILYQILRGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADK-------MTDHVGT 182
            ...||||||||||||||.|:||||||.|:.:|...:::|.||||:|: ||.       :|::|.|
Human   127 CYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARV-ADPDHDHTGFLTEYVAT 190

  Fly   183 MWYLAPEIIFLRGQYTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGI 247
            .||.||||:.....|||:||:|||||||||::::|.:|.|::|:.|:..::.|:|:|::|.:..|
Human   191 RWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCI 255

  Fly   248 SMERSRNYLEGYPLRQRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPH 312
            ...::||||...|.:.:..::.||...|.:|:||::|||...|.|||...:|:.||||....:|.
Human   256 INLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPS 320

  Fly   313 HHAEDTAPV-YDQNFENMVLPVKCWKELVSHEIRNFRP 349
            ......||. :|...::  ||.:..|||:..|...|:|
Human   321 DEPIAEAPFKFDMELDD--LPKEKLKELIFEETARFQP 356

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.