DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38c and mapk14

DIOPT Version :9

Sequence 1:	NP_996277.1	Gene:	p38c / 2768679	FlyBaseID:	FBgn0267339	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001005824.1	Gene:	mapk14 / 448296	XenbaseID:	XB-GENE-1018617	Length:	361	Species:	Xenopus tropicalis

Alignment Length:	353	Identity:	166/353 - (47%)
Similarity:	236/353 - (66%)	Gaps:	9/353 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREI 68
            |.|..:|::|||.||.|:.:..:|.|::|.|.......||...|:|:|.|||:....||.||||:
Frog     9 FYRQELNKTLWEVPDRYQNLTPVGSGAYGSVCSAFDTRTELRVAVKKLSRPFQSIIHAKRTYREL 73

  Fly    69 RLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILR 133
            ||||||.|.|||.||:|| .||.:..||..||||||||.|||:...:.::::|..::.::|||||
Frog    74 RLLKHMKHENVIGLLDVF-TPAKSFEEFNDVYLVTHLMGADLNNIVKCQKLTDDHVQFLIYQILR 137

  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYT 198
            |||||||||::||||||.|:|||.:.|::||||||:|...::||.:|.|.||.||||:.....|.
Frog   138 GLKYIHSAGIIHRDLKPSNLAVNEDCELKILDFGLARHTDEEMTGYVATRWYRAPEIMLNWMHYN 202

  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQ 263
            :.:|:||||||:|||:|.|.||.|.:::.|::.::.::|||..|.:..||.|.:|||::..|...
Frog   203 QTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPEPELLQKISSEAARNYIQSLPYMP 267

  Fly   264 RCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPV---YDQN 325
            :.:|..:|:|.:.||:||:||||.:..:||||||||:.|||.     ..:|..|..|:   |||:
Frog   268 KMNFEDVFLGANPQAVDLLEKMLVLDTDKRITAAEALAHPYF-----AQYHDPDDEPIAEPYDQS 327

  Fly   326 FENMVLPVKCWKELVSHEIRNFRPDQLD 353
            ||:..|.::.||.|...|:..|.|..||
Frog   328 FESRELDIEEWKRLTYEEVICFVPPPLD 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	163/347 (47%)
p38c	NP_996277.1	S_TKc	20..305	CDD:214567	140/284 (49%)
mapk14	NP_001005824.1	STKc_p38alpha	7..351	CDD:143382	163/347 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010