DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38c and srpk1a

DIOPT Version :9

Sequence 1:	NP_996277.1	Gene:	p38c / 2768679	FlyBaseID:	FBgn0267339	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_955944.1	Gene:	srpk1a / 323679	ZFINID:	ZDB-GENE-030131-2399	Length:	634	Species:	Danio rerio

Alignment Length:	297	Identity:	77/297 - (25%)
Similarity:	118/297 - (39%)	Gaps:	75/297 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 EEDAKGTYREIRLLKHMNHRNVISLLNVFHPP---AHNMMEF----------QQVYL-----VTH 104
            |||.:|..:..:||:..:|       |....|   |.:|.|:          |..|.     ...
Zfish   362 EEDEQGDLQYGQLLQEDHH-------NANAGPEDTAQSMYEYCNGAESPELDQACYSNGTSGQEQ 419

  Fly   105 LMDADL-----HRYSRSKRMSDQEIRIILYQILRGLKYIHSAG-VVHRDLKPCNIAVNGNSEVRI 163
            |.|.:|     |:.....|..:|....|....|       ||| ::...|.|.|.   ...:|:|
Zfish   420 LEDGELATEEQHQQKTRTRAREQNKDKIKDDKL-------SAGSLLVNPLDPLNA---DKIKVKI 474

  Fly   164 LDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYTKAIDVWSVGCILAELITDRVLFR---GENY 225
            .|.|.:.......|:.:.|..|.:.|::...|..|.| |:||..|:..||.|...||.   ||:|
Zfish   475 ADLGNACWVHKHFTEDIQTRQYRSLEVLLGSGYNTPA-DIWSTACMAFELATGDYLFEPHSGEDY 538

  Fly   226 ---VSQIRCLINIMG-TPTREFITGISMERSRNYLEGYPLRQRCDFHHLFMGYDVQAID-LMEK- 284
               ...|..:|.::| .|.:..:||   :.|:.:..     ::.|..|:........:| ||:|
Zfish   539 SRDEDHIALIIELLGVVPRKLVLTG---KYSKEFFS-----KKGDLKHITKLKPWGLLDVLMDKY 595

  Fly   285 ----------------MLEMVPEKRITAAEAMLHPYL 305
                            |||::||||.|||:.:.||:|
Zfish   596 EWPQEEAQTFSDFLLPMLELLPEKRATAADCLRHPWL 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	77/297 (26%)
p38c	NP_996277.1	S_TKc	20..305	CDD:214567	76/295 (26%)
srpk1a	NP_955944.1	PKc_like	72..632	CDD:304357	76/295 (26%)
srpk1a	NP_955944.1	S_TKc	82..>224	CDD:214567
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575939
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930