DRSC/TRiP Functional Genomics Resources

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Protein Alignment p38c and Mapk12

DIOPT Version :9

Sequence 1:NP_996277.1 Gene:p38c / 2768679 FlyBaseID:FBgn0267339 Length:356 Species:Drosophila melanogaster
Sequence 2:XP_006521121.1 Gene:Mapk12 / 29857 MGIID:1353438 Length:390 Species:Mus musculus


Alignment Length:369 Identity:145/369 - (39%)
Similarity:228/369 - (61%) Gaps:26/369 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 FVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREI 68
            |.|..:.::.||...:|:.::.:|.|::|.|.......|.|..|:|:|.|||:.|..||..|||:
Mouse    11 FYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGNKVAIKKLYRPFQSELFAKRAYREL 75

  Fly    69 RLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQILR 133
            ||||||.|.|||.||:|| .|..::.:|...|||...|..||.:..:.:.:|:..|:.::||:|:
Mouse    76 RLLKHMRHENVIGLLDVF-TPDESLDDFTDFYLVMPFMGTDLGKLMKHETLSEDRIQFLVYQMLK 139

  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQYT 198
            ||||||:|||:||||||.|:|||.:.|::||||||:|....:||.:|.|.||.|||:|....:||
Mouse   140 GLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNWMRYT 204

  Fly   199 KAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFI--------------TGISM 249
            :.:|:||||||:||:||.::||:|.:::.|::.::.|.|||..||:              .|:.:
Mouse   205 QTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKLQSAEVSGSGWWAGLGL 269

  Fly   250 ---------ERSRNYLEGYPLRQRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYL 305
                     .:::||:||.|..::.||..:......||::|:|:||.:..|:|:|||||:.|||.
Mouse   270 GGWPITLFPSQAKNYMEGLPELEKKDFASVLTNASPQAVNLLERMLVLDAEQRVTAAEALTHPYF 334

  Fly   306 RDLIEPHHHAEDTAPVYDQNFENMVLPVKCWKELVSHEIRNFRP 349
            ..|.:...  |..|..||.:|:::...::.||.:...|:.:|:|
Mouse   335 ESLRDTED--EPKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKP 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
p38cNP_996277.1 STKc_p38 4..349 CDD:143356 144/367 (39%)
S_TKc 20..305 CDD:214567 129/307 (42%)
Mapk12XP_006521121.1 STKc_p38gamma 11..376 CDD:143385 144/367 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0660
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000533
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24055
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
54.910

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