Protein Alignment p38c and Cdk6

DIOPT Version :10

• Sequence 1: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_034003.1
• Gene: Cdk6 / 12571
• MGIID: 1277162
• Length: 326
• Species: Mus musculus
• Alignment Length: 308
• Identity: 103/308 - (33%)
• Similarity: 164/308 - (53%)
• Gaps: 18/308 - (5%)

  Fly    11 ESLWEFPDIYEFVRFLGGGSFGQVAKVR-LRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHM 74
            :||......||.|..:|.|::|:|.|.| |:....:.|:||:......|.....|.||:.:|:|:
Mouse     4 DSLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRHL 68

  Fly    75 ---NHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRY---SRSKRMSDQEIRIILYQILR 133
               .|.||:.|.:|.  .........::.||...:|.||..|   .....:..:.|:.:::|:||
Mouse    69 ETFEHPNVVRLFDVC--TVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLR 131

  Fly   134 GLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKM--TDHVGTMWYLAPEIIFLRGQ 196
            ||.::||..||||||||.||.|..:.::::.||||:|:.:.:|  |..|.|:||.|||:: |:..
Mouse   132 GLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVL-LQSS 195

  Fly   197 YTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTRE-FITGISMERSRNYLEGYP 260
            |...:|:||||||.||:...:.||||.:.|.|:..:::|:|.|..| :...:::.|     :.:.
Mouse   196 YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDIIGLPGEEDWPRDVALPR-----QAFH 255

  Fly   261 LRQRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDL 308
            .:............|....||:.|.|...|.|||:|..|:.|||.:||
Mouse   256 SKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDL 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	103/308 (33%)
Cdk6	NP_034003.1	STKc_CDK6	11..300	CDD:270846	98/296 (33%)