Protein Alignment p38c and CDK3

DIOPT Version :10

• Sequence 1: NP_996277.1
• Gene: p38c / 2768679
• FlyBaseID: FBgn0267339
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 98/293 - (33%)
• Similarity: 164/293 - (55%)
• Gaps: 15/293 - (5%)

  Fly    18 DIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHRNVISL 82
            |:::.|..:|.|::|.|.|.:.|.|....|:|::....|.|.......|||.|||.:.|.|::.|
Human     2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRL 66

  Fly    83 LNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRII---LYQILRGLKYIHSAGVV 144
            |:|.|       ..:::|||...:..||.:|..|...|:..:.:|   |:|:|:|:.:.||..|:
Human    67 LDVVH-------NERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRVI 124

  Fly   145 HRDLKPCNIAVNGNSEVRILDFGLSRMCADKM---TDHVGTMWYLAPEIIFLRGQYTKAIDVWSV 206
            ||||||.|:.:|....:::.||||:|.....:   |..|.|:||.||||:.....||.|:|:||:
Human   125 HRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTAVDIWSI 189

  Fly   207 GCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLRQRCDFHHLF 271
            |||.||::|.:.||.|::.:.|:..:..::|||:.:...|::  :..:|...:|...|.....:.
Human   190 GCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVT--QLPDYKGSFPKWTRKGLEEIV 252

  Fly   272 MGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPY 304
            ...:.:..||:.::|:..|.:||||..|:.|||
Human   253 PNLEPEGRDLLMQLLQYDPSQRITAKTALAHPY 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	98/293 (33%)
CDK3	NP_001249.1	STKc_CDK2_3	3..286	CDD:270844	97/292 (33%)