DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38c and mapk13

DIOPT Version :9

Sequence 1:	NP_996277.1	Gene:	p38c / 2768679	FlyBaseID:	FBgn0267339	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_031751532.1	Gene:	mapk13 / 100144715	XenbaseID:	XB-GENE-490713	Length:	377	Species:	Xenopus tropicalis

Alignment Length:	350	Identity:	145/350 - (41%)
Similarity:	214/350 - (61%)	Gaps:	8/350 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EFVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYRE 67
            :|.:..:|::|||.|..|..:..:|.|::|.|.......|....|:|:|.|||:.|..||..:||
Frog     8 KFRKEEVNKTLWEIPLRYASLCLVGSGAYGSVCSAIDLKTGEKVAIKKLSRPFQSEIFAKRAFRE 72

  Fly    68 IRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSKRMSDQEIRIILYQIL 132
            :.|||||||.|||.||:|| ..|.:..:|...|||...|..||.:. ....:|:.:::.::||:|
Frog    73 LTLLKHMNHENVIGLLDVF-TSATSFNDFHNFYLVMPYMQIDLQKI-MGHHLSEDKVQYLVYQML 135

  Fly   133 RGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQY 197
            .||||||:||::||||||.|:|||.:.|::||||||:|....:||.:|.|.||.|||:|.....|
Frog   136 CGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAPEVILNWMHY 200

  Fly   198 TKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPLR 262
            .|.:|:||||||:.|::|.:.||:|::|:.|:..::.:.|.|..|||..:....::.|::..|..
Frog   201 NKTVDIWSVGCIMGEMLTGKTLFKGKDYLDQLTQILKVTGVPGPEFIQKLEDMAAKKYIQSLPKI 265

  Fly   263 QRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDT-APVYDQNF 326
            .:.:|..||......|:||:|||||:..|||:||.||:.|||..:.   |...|:| ||.||.:.
Frog   266 PKKEFSLLFPNASDLAVDLLEKMLELDVEKRLTATEALEHPYFDEF---HDADEETEAPPYDDSL 327

  Fly   327 ENMVLPVKCW--KELVSHEIRNFRP 349
            |...|.|:.|  ||....|:.|:.|
Frog   328 EGEKLSVEEWRSKEYTYEEVINYTP 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	144/347 (41%)
p38c	NP_996277.1	S_TKc	20..305	CDD:214567	122/284 (43%)
mapk13	XP_031751532.1	STKc_p38delta	9..352	CDD:143384	144/347 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020