DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38c and mapk13

DIOPT Version :9

Sequence 1:	NP_996277.1	Gene:	p38c / 2768679	FlyBaseID:	FBgn0267339	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_001337833.2	Gene:	mapk13 / 100002318	ZFINID:	ZDB-GENE-041111-17	Length:	362	Species:	Danio rerio

Alignment Length:	348	Identity:	148/348 - (42%)
Similarity:	217/348 - (62%)	Gaps:	7/348 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 EFVRVAINESLWEFPDIYEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYRE 67
            ||.|..||.::||.|..|..::.:|.|::|.|.......|:...|:|:|.|||:.|..||..|||
Zfish     6 EFSREEINSTVWEVPAKYVCLKQIGTGAYGSVCSSINNKTKEKVAIKKLHRPFQSEIFAKRAYRE 70

  Fly    68 IRLLKHMNHRNVISLLNVFHPPAHNMMEFQQVYLVTHLMDADLHRYSRSK-RMSDQEIRIILYQI 131
            :||||||.|.|||.||:|| .||..:.|||..|||...|..||   |:.| .:::..|:.::||:
Zfish    71 LRLLKHMKHENVIGLLDVF-TPATRLDEFQDFYLVMPYMYTDL---SKVKGLLTEDRIQFLVYQM 131

  Fly   132 LRGLKYIHSAGVVHRDLKPCNIAVNGNSEVRILDFGLSRMCADKMTDHVGTMWYLAPEIIFLRGQ 196
            |.||||||.||::||||||.|:|||.:.|::||||||:|....:||.:|.|.||.|||:|.....
Zfish   132 LCGLKYIHGAGIIHRDLKPGNLAVNQDCELKILDFGLARHTDAEMTGYVVTRWYRAPEVILNWMH 196

  Fly   197 YTKAIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGISMERSRNYLEGYPL 261
            ||:.:|:||||||:.|:...:.||:|::|:.|:..::.:.|||..||:..:....:::|:...|.
Zfish   197 YTQTVDIWSVGCIMGEMFNGKTLFKGKDYMDQLTQIMKVAGTPGPEFVEKLESPEAKSYVRSLPH 261

  Fly   262 RQRCDFHHLFMGYDVQAIDLMEKMLEMVPEKRITAAEAMLHPYLRDLIEPHHHAEDTAPVYDQNF 326
            ....||..||.....:|::|:||||.:..:.|:||:.|:.|.|...|.:|....|.||  ||.::
Zfish   262 YPHRDFSTLFPRASKKAVELLEKMLVLDADARLTASGALAHSYFDGLRDPDDWPEPTA--YDDSY 324

  Fly   327 ENMVLPVKCWKELVSHEIRNFRP 349
            :|..||::.||.|...|:|:|.|
Zfish   325 DNATLPLEEWKRLSFKEVRSFVP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38c	NP_996277.1	STKc_p38	4..349	CDD:143356	146/345 (42%)
p38c	NP_996277.1	S_TKc	20..305	CDD:214567	122/285 (43%)
mapk13	XP_001337833.2	PKc_like	7..347	CDD:304357	146/345 (42%)
mapk13	XP_001337833.2	S_TKc	23..305	CDD:214567	122/285 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850