DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33337 and CG17707

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_001162627.1	Gene:	CG17707 / 5740408	FlyBaseID:	FBgn0025835	Length:	990	Species:	Drosophila melanogaster

Alignment Length:	787	Identity:	164/787 - (20%)
Similarity:	286/787 - (36%)	Gaps:	236/787 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 ADYFQNVTLNDLSLFD------SRLPTQADLLCLNDLTKLVSALQGGQYWAFKMIDAWGGIPSGI 102
            |:|||.|.    :|:|      |.:.|.....|..::...::||.....||.|..|:.|.....:
  Fly   251 ANYFQLVA----NLYDHFYWQISEIRTNVHTGCGLEMQAYLTALHSSYEWAQKAYDSSGRYRGQL 311

  Fly   103 FTGNVYDLGNFDECINIKKDSIRGKYCFLDVS--PAKILGVESSLAGILKIKTATCFPASCSATH 165
            ..||...||....|..:.:.|:..:....|:.  .|.:.....||...:.:....|.|.|||
  Fly   312 LFGNDKWLGQLSFCYELNRQSLTEERQHFDLQFYVADVALHLPSLNRSMLLSLGECLPKSCS--- 373

  Fly   166 MNKFVDTILKRILNVSIPSTAMSISDDSCQTAESEPWSGLTILTI-------------VILSLM- 216
                 |..:|.||::...:..:::......:.:..|...|.:.|:             |.:|.|
  Fly   374 -----DIDVKSILSLDPYARMLTVLGAHNTSMQQPPLQILHVRTVPGIYSHWRQLKFQVFISFML 433

  Fly   217 --GVIVAIATLY----------------------------------------------------- 226
              .:::.:|:.|
  Fly   434 TLFLVILVASYYQLKIDERRLVVAPIAAISGKCDGTSTKNDVFYGKSFELFQMRPLGCTSSSTDD 498

  Fly   227 ------------------------------------------DY-------------FLVKSQDQ 236
                                                      ||             :..|....
  Fly   499 PEVDVNGNRQRCGDSSDMENGVQREFADPNTSTSVGEKSEMGDYQMETGSCAGGTGTYEAKQSVA 563

  Fly   237 LHTAVKL-FSARANSCALFRIVVNQSNPNVIECLHGIRCMSLFWVVWIHQYDNVFSAPNINRF-R 299
            ||..:.| |:.:.|:.|:..|  |::......||||:|..|:.|.:.:|.|..:| |...|:| |
  Fly   564 LHQQILLCFALQTNAKAILNI--NKTKEIHTACLHGLRVFSVLWTMMVHTYLQMF-AIGENKFER 625

  Fly   300 FLS----WLQTPFTMFFLEGN--FSVDSFFFIGGFLVSLNALGTMEKNNGKINVP---------- 348
            .::    |.|       :.||  |||||||||.|.||::..|    |.|.|....
  Fly   626 IITERSFWYQ-------VIGNATFSVDSFFFISGLLVTMLYL----KQNRKYPTETCLFIKSCFS 679

  Fly   349 ---RMYIRRFIRIFPILAMSILVYTQLTGVLG-DGPLFKGGYSKKASCAKTWYMTLLFVVNF--A 407
               .|.:.|::|:.|:. :.::::.......| |..:|:....:..:|...|:..:|::.|:  .
  Fly   680 ESLMMLLYRYLRLTPVY-LFVVIFNDFAVRQGLDTSVFQPAKIEHNTCRMYWWRNILYINNYFPQ 743

  Fly   408 NDMCLDHTWYLAVDMQLFLISPILLFALYKWGKKAAAAIGVLIVLLSGCLFATMMVNHYSIKSLD 472
            .:||:..:||:|.:||.::::.:||....|:.|  |.||.:.:.|||.          :||..:
  Fly   744 TEMCMMWSWYMANEMQFYVMAALLLALARKYFK--AVAITLFVFLLSS----------WSISGI- 795

  Fly   473 FSLQKKTYFYTH-----------THAAPW------LIGFLYGYFVFLNK-----GRKFKMNWIAV 515
            .||   ||.|||           .:..||      ::|...||.::..|     .|:..:
  Fly   796 ISL---TYQYTHKVSLPFESFDFLYDKPWQRVGSYIMGMCTGYVLYKVKTPPLISRRLNL----- 852

  Fly   516 WSGWILCLAMLFTSIFALYPKLESGKPWLMTTLEVSSYYT-LTRVGWPMAVGWVVFACMQGYGGM 579
             |.|...|.:|...:|.::      :..|.||  .|::|. :....:...:.|:|.:|..|....
  Fly   853 -SLWACSLFVLLIVVFGVW------EGHLGTT--SSAFYVGVAHTAFGCGLVWIVLSCCWGLVPT 908

  Fly   580 ANTFLSSPLWQPISKLSYSIYIWHSFIQEINKRIVRTNTYFSNYQVMLNFWSTMGFTVLFSYLLY 644
            .|..||..:..|:|:|:|..|:.|..|..|....:....:.||..::..|......:...::::.
  Fly   909 VNAILSYRVMWPLSRLTYCAYLIHPIIMFICSSHMSGTVHLSNPLILTLFLGNAVVSFGCAFVIS 973

  Fly   645 LLIEAPI 651
            ...|||:
  Fly   974 AFFEAPV 980

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	24/112 (21%)
		Acyl_transf_3	266..645	CDD:280013	106/424 (25%)
		OafA	300..666	CDD:224748	95/397 (24%)
CG17707	NP_001162627.1	NRF	294..399	CDD:214781	24/112 (21%)
		Acyl_transf_3	595..973	CDD:280013	105/420 (25%)
		OafA	597..985	CDD:224748	106/427 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	6	5.920