DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33337 and CG32645

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster

Alignment Length:	773	Identity:	173/773 - (22%)
Similarity:	288/773 - (37%)	Gaps:	208/773 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 CLNDLTKLVSALQGGQYWAFKMIDAWGGIPSGIFTGNVYDLGNFDECINIKKDSI---------- 124
            |..|:...:..|...:.||.||.||.|...||.|.||.|.:|:...|..|....|
  Fly   106 CSRDMRSYLGGLSDAKMWAVKMDDASGHYTSGFFYGNNYWMGSLALCDAIDDGQIVAPGKDNSSS 170

  Fly   125 ---------------------RGKYCFLDVSPAKILGV--------ESSLAGILK-IKTATCFPA 159
                                 :|.....:..|..:.|.        |:....:|: |....|.|:
  Fly   171 AASSPESETKNSGLPFAAAHTQGYSSVYNAPPPFVPGFYVIKMQLNETLPTQVLRIIYVGMCLPS 235

  Fly   160 SCSATHMNKFVDTILKRILNVSIPSTAMSISDDSCQT-AESEPWSGLTI-LTIVILSLMGVIVAI 222
            |||...:.:     :....:|.:||..:.:.|....| .|...|:..|. |.||:.|::..::..
  Fly   236 SCSIADIGQ-----MSSRAHVELPSRDLRVLDIRVPTDKEFNIWADKTFCLLIVVSSIVLGLICC 295

  Fly   223 ATLYDYFL-------VKSQDQ-------------------------------------------- 236
            .||::.:|       ::.||:
  Fly   296 GTLFEIYLRRKLKEALRRQDKEMMNNSETSSGIGCASSDYSDTMTAHDDPLKQSDHSQSSNSLKQ 360

  Fly   237 -------------------------------------------------LHTAVKL--------- 243
                                                             ||...||
  Fly   361 LDALVLNLPPNDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKLSIYSELLLS 425

  Fly   244 FSARANSCALFRIVVNQS-NPNVIECLHGIRCMSLFWVVWIHQYDNVFS-APNINRFRFLSWLQT 306
            |||..|    |..:.::: ..:.|.|:||:|..|:.||:..|....||. :.|:...:.:.  |.
  Fly   426 FSAITN----FNAICDRNVGADTIPCIHGLRAFSMAWVILGHTCIVVFKYSDNMEMRKEVE--QN 484

  Fly   307 PFTMFFLEGNFSVDSFFFIGGFLVS-----------LNAL--GTMEKNNGKINVPRMYIRRFIRI 358
            .|......|.||||:||||.|||:|           ||.|  |..|...|..:...:...||:|:
  Fly   485 FFFQAITNGPFSVDTFFFISGFLISYIYFRTNAKGKLNKLSKGANEFTAGTAHFFGLVAYRFMRL 549

  Fly   359 -FPILAMSILVYTQLT-GVLGDGPLFKGGYSKKASCAKTWYMTLLFVVNF--ANDMCLDHTWYLA 419
             .|.|  .:|...|:| ..|....:|........:|...|:..:|::...  .::||:..:||||
  Fly   550 TAPYL--FVLGVVQVTMKYLATYSIFDPPTMDHITCPDYWWRNILYINTLFPVDEMCMLWSWYLA 612

  Fly   420 VDMQLFLISPILLFALYKWGKKAAAAIGVLIVLLSGCLFATMMV---NHYSIKSLDFSLQKKTYF 481
            .|.|.::|..|:|....:..|  .:||..|:.|:...:...::.   ||........:|..|.|.
  Fly   613 NDTQFYMIGAIILIVGVRHFK--LSAITTLVFLVLSWITTAVIAFTNNHRPNTDDPLALFDKIYD 675

  Fly   482 YTHTHAAPWLIGFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAMLFTSIFALYPKLESGKPWLMT 546
            ...|...|:|||...|:.:| ....|.::..:.|.:.|.|.:..||..:|.|| |.:      ::
  Fly   676 KPWTRLGPYLIGMAVGWILF-RTNCKIRLPKLTVATAWTLAMLNLFVLVFGLY-KAD------LS 732

  Fly   547 TLEVSSYYTLTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQPISKLSYSIYIWHSFIQEINK 611
            ....::|.:|:...|.:::.|:..||..||||..|:.||:|...|.|:::|..|:.|..:  |..
  Fly   733 QFTAAAYSSLSHSAWALSLAWITIACSTGYGGYINSLLSAPCLYPFSRVTYCAYLVHPIV--IRS 795

  Fly   612 RIVRTNTYF---SNYQVMLNFWSTMGFTV---LFSYLLYLLIEAPIGGLDRLLRPKKK 663
            ..:.::...   .:..|::.|    |.||   ..|:::.:..|||:..:.::|.|.:|
  Fly   796 MALNSDAPLHLGGDLMVVMFF----GLTVASYFLSFVVSMSFEAPVVTMLKILSPSRK 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	32/150 (21%)
		Acyl_transf_3	266..645	CDD:280013	110/405 (27%)
		OafA	300..666	CDD:224748	104/390 (27%)
CG32645	NP_727670.1	NRF	121..272	CDD:214781	34/155 (22%)
		Acyl_transf_3	445..831	CDD:280013	110/405 (27%)
		OafA	450..853	CDD:224748	113/420 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
	8	7.770