DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33337 and oac-20

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_507007.3	Gene:	oac-20 / 185375	WormBaseID:	WBGene00009488	Length:	719	Species:	Caenorhabditis elegans

Alignment Length:	747	Identity:	203/747 - (27%)
Similarity:	309/747 - (41%)	Gaps:	186/747 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 IEFADYFQNVT--LNDLSLFDSRLPTQADLLCLND-------------------LTKLVS----A 80
            |:..:||.|..  ...|.|..|:..|..:..|.||                   |:|..|    .
Worm    11 IQLGNYFANAKEWKETLLLHHSKNLTGVNPQCNNDTETWLHSLDILTEVSLECILSKKCSKKEEL 75

  Fly    81 LQGGQYWAFKMIDAWGGIPS-GIFTGNVYDLGNFDECINIKKDSIRGK--------YCFL----- 131
            |....::|.:.:|::|..|| |:|...:...|::.||     :.|.||        ||::
Worm    76 LLRDNFYALEQLDSFGKFPSIGLFEVPLIFDGSYQEC-----ERISGKSETKYETNYCYVLLIPG 135

  Fly   132 ------------DVSPAKILGVESSLAGILKIKTATCFPASCSATHMNKFVDTILKRILNVSIPS 184
                        |:||..:.           .::|.|.|.||:...::..::.|      ..||.
Worm   136 KNSSHCHETKSGDLSPTTLF-----------FRSAVCMPNSCNQREISDIINEI------SDIPF 183

  Fly   185 TAMSISDDSCQTAESEPWSGLTILTIVILSLMGVIVAIATLYDYFL--------VKSQDQLHTAV 241
            ||......|....::..:.|.::..||::|    |..:||..||.|        .:.:::.|..:
Worm   184 TACGSQCSSYPVEKNSAFWGFSVFMIVMIS----IAILATSVDYILDAIATDEEQREKNKRHLLL 244

  Fly   242 KL---FSARANSCALFRIVVNQSNPNVIECLHGIRCMSLFWVVWIHQYDNVFSAPNINRFRFLSW 303
            |:   ||...|  |...:.|.:.....|:||..||.:|:.|||..|...|:.       |..:..
Worm   245 KILISFSLWTN--AELILSVKEQKVGFIKCLDCIRFLSMLWVVSGHTVSNIM-------FPDVLL 300

  Fly   304 LQTPFTMFF-----LEGNFSVDSFFFIGGFLVSLNALGTMEKNNGKINVP----RMYIRRFIRIF 359
            ..|.||..|     |....|||:||.:.|.:||........|:: :|..|    ..|:.|::|:.
Worm   301 PVTTFTKHFWNHLLLNAFVSVDTFFLLSGIVVSYLFFKNRMKSS-QIKSPLTWILFYVHRYLRLT 364

  Fly   360 P---ILAMSILVYTQLTGVLGDGPLFKGG-----YSKKASCAKTWYMTLLFVVNFAND--MCLDH 414
            |   |.....:||::..    .||....|     ||.: ||.|||:..||::.||.:.  .|...
Worm   365 PPYMIFLGFYIVYSEYV----QGPTAAAGLNAAIYSVE-SCKKTWWRNLLYINNFGDSTHACYAI 424

  Fly   415 TWYLAVDMQLFLISPILLFAL---YKWGKKAAAAIGVLIVLLSGCLFATMMVNHYSIKS------ 470
            |||||||.||:||:||:|.||   :.||..|.||         ||  |..:|..|.:.:
Worm   425 TWYLAVDTQLYLIAPIVLIALWFSFVWGALAVAA---------GC--AGSIVTVYVLYAEYHLPA 478

  Fly   471 --------LDFSLQKKTYFYTHTHAAPWLIGFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAMLF 527
                    |||.  |..|........|:|||.|.||.:.:...|:.:::|.....||::...:..
Worm   479 DQFGKGSLLDFG--KILYQKPWVRCTPYLIGLLVGYGLAVFGKRRVRLHWALAVVGWLIAFGIAV 541

  Fly   528 TSIFAL--YPKLESGKPWLMTTLEVSSYYTLTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQ 590
            ..:|:.  |.|   |..|  :..|.::||..:|..|.:||.||:.|...|:||..|.|:|.|:||
Worm   542 ACLFSTNDYDK---GAVW--SDFEKATYYNFSRFFWAIAVSWVIVANHMGWGGPINNFMSHPIWQ 601

  Fly   591 PISKLSYSIYIWHSFIQEINKRIVRTNT-YFSNYQVMLN--------------FWSTMGFTVLFS 640
            |..||||..||.|.|:......|..... |:|.:||.:.              |||.: |.:...
Worm   602 PFGKLSYCAYIVHFFLISWYTNISEAPMHYYSTFQVWIYYAVPVTIIAYIFAFFWSCL-FEIPTL 665

  Fly   641 YLLYLLIEA-----------PIGGLDRLLRPK 661
            .|..:||||           .:|.|::.:.|:
Worm   666 KLEKMLIEAILGAGHTRASGKVGELEKPVEPR 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	29/136 (21%)
		Acyl_transf_3	266..645	CDD:280013	135/431 (31%)
		OafA	300..666	CDD:224748	130/426 (31%)
oac-20	NP_507007.3	NRF	80..192	CDD:214781	28/133 (21%)
oac-20	NP_507007.3	Acyl_transf_3	270..654	CDD:376607	130/414 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.680