DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33337 and oac-3

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_506446.2	Gene:	oac-3 / 182290	WormBaseID:	WBGene00007361	Length:	691	Species:	Caenorhabditis elegans

Alignment Length:	718	Identity:	187/718 - (26%)
Similarity:	308/718 - (42%)	Gaps:	128/718 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LEEYQRLRKLKPLGIEFADYFQNVT---LNDLSLFDSRLP--TQADLLCL---NDLTKLVSALQG 83
            |.:|.::...:|.. .|.:| .:||   ..|:..:.|.:.  |.|...||   |....:::.|:.
Worm    22 LFDYGKIESFEPFS-SFINY-SHVTPECTKDMKTWISSIEQFTAASSDCLFFKNCTASILNILKD 84

  Fly    84 GQYWAFKMIDAWGGIPSG--IFTGNVYDLGNFDECINIKKDSIRGKYCFLDVSP---AKILGVES 143
            ..| |.:..||:..|||.  :....|:| |::.||..|........||::.:.|   |...|...
Worm    85 NIY-AIQQYDAFAKIPSAGLLEVSLVFD-GSYQECHRISGVKYETNYCYVLLVPGRNANCSGGSI 147

  Fly   144 SLAGI-LKIKTATCFPASCSATHMNKFVDTI-LKRILNVSIPSTAMSISDDSCQTAESEPWSGLT 206
            ..||. :..:.|.|.|.||:::      ||: |...|: ::|.||.:.........:...:.|.:
Worm   148 QNAGTSVAFRRAVCMPKSCASS------DTVDLYNQLS-ALPLTACATFCSQRDVPKDSAFWGFS 205

  Fly   207 ILTIVILSLMGVIVAIATLYDYF----------LVKSQDQLHTAVKLFSARANSCALFRIVVNQS 261
            ....||:|    .|.:||..||.          .::....|:..:..||...|:..:..:   .|
Worm   206 AFMFVIVS----TVILATTVDYLRESVYDISSKSIEKSASLYRLLYSFSFWTNASTILNV---SS 263

  Fly   262 NPNV-IECLHGIRCMSLFWVVWIHQYDNVFSAPNINRFRFLSWLQTPF--------TMFFLEGNF 317
            .|.. |:||..||.:|:.||:..|.         :|.|.|...|. |.        ..||:...|
Worm   264 QPATHIKCLDCIRGLSMAWVLSGHM---------LNYFAFADTLM-PIKSFANYFADYFFMNAVF 318

  Fly   318 SVDSFFFIGGFLVSLNALGTMEKNNGKINVPR----MYIRRFIRIFPILAMSILVYTQLTGVLGD 378
            |||:||.:.|..|:.:.. .::.....:..|.    .|:.|::|:.|...:.|..|. :..:...
Worm   319 SVDTFFLVSGITVAYSFF-RLKPTTKTLKSPATWILFYVHRYVRLTPPYIIFIGFYA-VYALYIQ 381

  Fly   379 GP----LFKGGYSKKASCAKTWYMTLLFVVNFAN--DMCLDHTWYLAVDMQLFLISPILLFALYK 437
            ||    ||.....:..:|..:|:..|:::.||.|  :.|...:||||||.||:|::||||.|| .
Worm   382 GPLAASLFNFTVLQVEACKASWWRNLIYINNFDNGENPCYGPSWYLAVDTQLYLVAPILLVAL-T 445

  Fly   438 WGKKAAAAIGVLIVLLSGCLFATMMV----NHYSIKSLDFSLQK--KTYFYTH----THAAPWLI 492
            |     ..|..|:|.:.||:.:.::|    ..:.:.:..|:...  |..||.:    |...|:|:
Worm   446 W-----TPIAGLVVSMVGCIGSMIIVFILYQKFDMPADSFNADSSGKFNFYVYQKPWTRCPPYLV 505

  Fly   493 GFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAMLFTSIFAL--YPKLESGKPWLMTTLEVSSYYT 555
            |.|.|||:........|::::......:|.:.::|..:.|.  |.:.:....|...|     ||.
Worm   506 GILGGYFLSRFATSPVKLSFVKKLIPMLLAVGLIFACLTANIGYDQGDHWSSWTKAT-----YYN 565

  Fly   556 LTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQPISKLSYSIYIWHSFIQEINKRIVRTNTYF 620
            .:|..|.::|.|::.:|..|:.|....|:|.|:|||:.:||||.||.|..:.          .||
Worm   566 FSRFFWALSVLWIILSCHYGWAGPIGNFMSHPIWQPLGRLSYSAYIVHLMVV----------YYF 620

  Fly   621 SNY-QVMLNFWSTMG-----------FTVLFSYLLYLLIEAPIGGLDR-----LLR----PKKKA 664
            .|. ...|:|.||..           .|.:|::....|.|.|:..|::     |||    |:||.
Worm   621 LNVGDKPLHFVSTWQVYVYYILPATILTYIFAFFWSCLFEIPVVKLEKFLLEILLRKKRLPEKKT 685

  Fly   665 PAE 667
            ..|
Worm   686 GKE 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	32/117 (27%)
		Acyl_transf_3	266..645	CDD:280013	114/420 (27%)
		OafA	300..666	CDD:224748	113/416 (27%)
oac-3	NP_506446.2	NRF	85..191	CDD:214781	32/114 (28%)
oac-3	NP_506446.2	Acyl_transf_3	269..653	CDD:376607	114/416 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.680