DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33337 and oac-14

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_509701.1	Gene:	oac-14 / 181226	WormBaseID:	WBGene00008602	Length:	710	Species:	Caenorhabditis elegans

Alignment Length:	739	Identity:	195/739 - (26%)
Similarity:	314/739 - (42%)	Gaps:	148/739 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 IEFADYFQNVTLNDLSLFDSRLPTQADLLCLNDLTKLVSALQ----------------------- 82
            :::.|.|:...|:.||      |.     ||||....:.:|:
Worm    20 LDWKDIFKPKPLHGLS------PQ-----CLNDTQTWIKSLELFAGVSEACLKKQTCSLKELKIL 73

  Fly    83 GGQYWAFKMIDAWG--GIPSGIFTGNVYDLGNFDECINIKKDSIRGKYCFLDVSPAKILGV---- 141
            ....:|.:.:|::|  .:|..:....:|| |::.||..:........||:|.:.|.|....
Worm    74 KANLYAIQELDSFGKLPVPGMLEVATLYD-GSYQECKRVSGVKYNTNYCYLMLKPGKNASCSASG 137

  Fly   142 ESSLAGILKIKTATCFPASCSATHMNKFVDTILKRILN--VSIPSTAMSISDDSCQTAESEPWSG 204
            .||...:|.::.|.|.|.||   :.::.:|     |.|  ...|.||........:..:..|:.|
Worm   138 SSSAYSMLPMRLAVCLPDSC---NQHEIID-----IFNQLSPYPFTACHAYCSEYEVKKDTPFWG 194

  Fly   205 LTILTIVILSLMGVIVAIATLYDY-----FLVKSQDQLHTAVKL---FSARANSCALFRIVVNQS 261
            .:|..||    |.||...|:|.||     :.:||..:.:..:|:   ||...|:..|  :.|.:.
Worm   195 FSIFLIV----MVVIALAASLTDYIRDTVYGIKSIKERNVFLKILLSFSLWTNAELL--LSVKEQ 253

  Fly   262 NPNVIECLHGIRCMSLFWVVWIHQYDNVFSAPNINRFRFLSWLQTP---FTMFFLEGNFSVDSFF 323
            .|..|:.|..||..|:.|||..|.:..:..:..     |:..:..|   :....|....|||:||
Worm   254 KPGFIKSLDCIRLFSMCWVVTGHSFIYLVLSDT-----FMPVIDFPKHFWNHLLLNAFVSVDTFF 313

  Fly   324 FIGGFLVSLNALGTMEKNNGKINVP----RMYIRRFIRIFPILAMSILVYTQLTGVLGDGPLFKG 384
            .:.|.:::.....|..|....:| |    ..|:.|::|:.|.:.:.|..:|..      .|..:|
Worm   314 VLSGLVLTYMFFKTTPKKKMIVN-PVTWIMFYVHRYLRLTPPIMLFIGFFTVY------APYIQG 371

  Fly   385 GYS---------KKASCAKTWYMTLLFVVNFA--NDM-CLDHTWYLAVDMQLFLISPILLFALYK 437
            .:|         :...|..||:..||::.:||  |.| |...|||||||.||:|::||:|..||
Worm   372 PFSASQMNQLVMEADECKTTWWQNLLYINDFASSNSMGCYGPTWYLAVDTQLYLVAPIVLIGLY- 435

  Fly   438 WGKKAAAAIGVLIVLLSGCLFAT-MMVNHYSIKSLDFSLQKKTYFYTHTHAAPW------LIGFL 495
              ...|...|:::....|.:..| ::.:.|::.:..|.....|.|:|..:..||      |:|.|
Worm   436 --FSFAVGTGLIVAGCVGSIITTYILFSVYNLPADMFGNGSGTNFFTIAYEKPWVRCPPYLVGML 498

  Fly   496 YGYFVFLNKGRKFKMNWIAVWSGWILCLAMLFTSIFALYPKLESGKPWLMTTLEVSSYYTLTRVG 560
            .||.:.:...||.::||:...:|||:.:.:....:||.| ..:.|..|.:.|.  .::|...|:|
Worm   499 TGYLLAVYGNRKIRLNWVLSLAGWIIAVVIAGFCLFATY-DYDKGSHWSVFTR--GTFYNFHRLG 560

  Fly   561 WPMAVGWVVFACMQGYGGMANTFLSSPLWQPISKLSYSIYI--WHSFIQEINKRIVRTNTY---- 619
            |.|.:.|||.|...|:||..:.|:|.|:|||..:|||..||  |......:|.....|:.|
Worm   561 WGMFICWVVAANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWVVLFWFLNVGGHATHYYSALE 625

  Fly   620 ----------FSNYQVMLNFWSTMGFTVLFSYLLYLLIEAPIG-GLDRLLRPKKKA-PAENKPMT 672
                      |.:| :...|||.: |.:....|..:||||.:| |     ||..|. |.|....|
Worm   626 VFTYTSIPATFLSY-IFAFFWSCL-FEIPTLKLEKMLIEAILGTG-----RPSNKVEPIETGKTT 683

  Fly   673 NSDRVGEGHGHDVDLSNQRELEGN 696
            .              ..:::||||
Worm   684 P--------------ILEKKLEGN 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	28/118 (24%)
		Acyl_transf_3	266..645	CDD:280013	119/420 (28%)
		OafA	300..666	CDD:224748	119/409 (29%)
oac-14	NP_509701.1	NRF	76..183	CDD:214781	28/115 (24%)
oac-14	NP_509701.1	OafA	252..656	CDD:224748	119/423 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.680