DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33337 and oac-7

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_507120.3	Gene:	oac-7 / 180096	WormBaseID:	WBGene00007835	Length:	702	Species:	Caenorhabditis elegans

Alignment Length:	712	Identity:	184/712 - (25%)
Similarity:	306/712 - (42%)	Gaps:	105/712 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKILSFILLSGLVLIGAIQSED-RSVLEEYQRLRKLKPLGIEFADYFQNVTLNDLSLFDSRLPT 64
            :.|.....|.:..:.||.::::. ..:|:.......|..:..:.|    |.|...|.........
Worm     2 LYKYFYIFLFTFAIFIGTLEADSWEKILKSENASNSLNEVNAQCA----NDTRTWLQSLKLVAEV 62

  Fly    65 QADLLCLNDLTKLVSALQGGQYWAFKMIDAWGGIP-SGIFTGNVYDLGNFDECINIKKDSIRGKY 128
            ..|.|......|....:....::|.:.:||:|.:| ||||...:...|::.||..|........|
Worm    63 SVDCLISRKCNKKEIQIIKDNFYAIEQLDAFGKLPSSGIFEVPLIFDGSYQECQRISGKKYETNY 127

  Fly   129 CFLDVSPAK-----ILGVESSLAGILKIKTATCFPASCSATHMNKFVDTILKRILNVSIPSTAMS 188
            |:|.:.|.:     |.|....|......::|||...||::..:.:..:.:      ..:|.||.:
Worm   128 CYLVLVPGRNSSCSIGGGGGFLPSAAFFRSATCMSVSCTSEDLPQLFNQL------PLMPFTACA 186

  Fly   189 ISDDSCQTAESEPWSGLTILTIVILSLMGVIVAIATLYDYF--LVKSQ----DQLHTAVKL---F 244
            ....|....:...:.|.:....|::|    |:.:||..||.  .:|::    .|.:..:|:   |
Worm   187 AFCSSFPVEKDSAFWGFSAFMCVMIS----ILVLATFIDYLKDAMKNEHSPPPQPNLIMKMLLTF 247

  Fly   245 SARANSCALFRIVVNQSNPNVIECLHGIRCMSLFWVVWIHQYDNVFSAP-----NINRFRFLSWL 304
            |...|:..|  :.|.:..|..|:||..||.:|:.|||..|.:  .|..|     :::.|....|
Worm   248 SLWTNAGVL--LSVKEQKPGFIKCLDCIRFLSMLWVVTGHTF--TFVIPPDTLLSMSHFTDHFW- 307

  Fly   305 QTPFTMFFLEGNFSVDSFFFIGGFLVSLNALGTMEKNNGKINVPR----MYIRRFIRIFPILAMS 365
                ....|....|||:||.:.|.:|:........|:: :|..|.    .|:.|::|:.|...:.
Worm   308 ----NHLLLNAFVSVDTFFLLSGIVVAYLFFKQKHKSS-QIKSPLTWIIFYMHRYLRLTPPYMIF 367

  Fly   366 I---LVYTQLTGVLGDGPL----FKGGYSKKASCAKTWYMTLLFVVNF--ANDMCLDHTWYLAVD 421
            |   :||    |....||.    |....|..|:|...|:..|.::.|.  ::..|...:||||||
Worm   368 IGFYIVY----GKYVQGPFSASQFNTLLSSIATCESYWWKNLFYINNMGDSSTACYAPSWYLAVD 428

  Fly   422 MQLFLISPILLFALYKWGKKAAAAIG--VLIVLLSGCLFATMMVNHYSIKSL--DFSLQKKT-YF 481
            .||::.:||:|..||     .:|.||  ::.|.:.|.|....::  |||..|  ||.....| ..
Worm   429 TQLYIFAPIILVGLY-----YSAIIGSSLIAVGMIGSLVTVYIL--YSIYDLPADFFGNGNTNLL 486

  Fly   482 YTHTHAAPW------LIGFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAMLFTSIFALYPKLESG 540
            |...:..||      |||.|.||.:.:...||.:::|.....||::...:....:|:.| ..:.|
Worm   487 YDMIYHKPWIRCPPYLIGLLIGYGLAVFGQRKIRIHWFLAVIGWLVAFGLGMACMFSTY-DYDKG 550

  Fly   541 KPWLMTTLEVSSYYTLTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQPISKLSYSIYIWHSF 605
            ..|  :....::||..:|:.|.:||.||:.|...|:||..:.|:|.|:|||:.:|||..||.|.|
Worm   551 AYW--SIFARATYYNFSRIAWSIAVSWVIVANHMGWGGPIDAFMSHPMWQPLGRLSYCAYIVHFF 613

  Fly   606 ----IQEINKRIVRTNTYFSNYQVMLN--------------FWSTMGFTVLFSYLLYLLIEA 649
                ...||...:.   ::|.:||.:.              |||:: |.:....|..::|||
Worm   614 TLFWYLNINDSSMH---FYSTFQVFIYYAVPACLLSYIFAFFWSSL-FEIPILKLKKMMIEA 671

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	29/116 (25%)
		Acyl_transf_3	266..645	CDD:280013	122/425 (29%)
		OafA	300..666	CDD:224748	112/392 (29%)
oac-7	NP_507120.3	NRF	83..191	CDD:214781	28/113 (25%)
oac-7	NP_507120.3	OafA	261..666	CDD:224748	123/430 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.680