DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33337 and oac-50

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_001309487.1	Gene:	oac-50 / 179284	WormBaseID:	WBGene00020864	Length:	731	Species:	Caenorhabditis elegans

Alignment Length:	809	Identity:	171/809 - (21%)
Similarity:	298/809 - (36%)	Gaps:	229/809 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ILSFILLSGLVLIGAIQSEDRSVLEEYQRLRKLKPLGIEFADY---------------------- 46
            |:.:|||.   :.|.:.::.|     .|.|.......||..||
Worm    10 IIFWILLQ---IEGVVVNDSR-----IQALLLNSSFSIEQLDYRNKNEIRSGEVATPDLCKTLMK 66

  Fly    47 --FQNVTLNDLSLFDSRLPTQADLLCLNDLTKLVSALQGGQYWAFKMIDAWGGIPS-GIFTGNVY 108
              |||:.    ||.:.......|  ||:.|.:|               ||:...|: |  :.|:|
Worm    67 RWFQNLN----SLKNGTCKNSDD--CLDALDQL---------------DAFARYPAPG--SPNIY 108

  Fly   109 DLGNFDECINI-KKDSIRGKYCFLDVSPAKILGVESSLAGILK-IKTA--TCFPASCSAT----- 164
            | |:|.:|.:: :|...|.|||:|..:..|:...|...:.:.| .:||  .|.|..|...
Worm   109 D-GSFRKCNDLNEKGGHRRKYCYLIQADEKMNCREEYHSILFKPNRTAFGFCGPEICHGKDYASM 172

  Fly   165 --HMNKFVDTILKRILNVSIPSTAMSISDDSCQTAESEPWSGLTILTIVILSLMGVIVAIATLYD 227
              .|.|....::.|.:..:.           | |....|...........|.::|.:|..::|||
Worm   173 FGSMEKTFHFLMDRPVCAAF-----------C-TVRDIPKKLQFYFFTAFLIMLGSVVFFSSLYD 225

  Fly   228 Y-----FLVKSQDQLHTAVKLFSAR-ANSCALF---RIVVNQSNPNVIECLHGIRCMSLFWVV-- 281
            |     :.:.|:.:     |:|..| ..|.:|:   ..:.....|:.|..|..||.::..|||
Worm   226 YVRDTRYRLSSESE-----KVFGQRIILSFSLWSNIEFIFQDKRPDYIRSLDCIRAITFTWVVGQ 285

  Fly   282 ----WIHQYDN---------------VFSAPNINRFRFLSWLQTPFTMFFLEGNFSVD------- 320
                .:..||:               :.|...|..:.|:|.|...:|  ||:|..|:|
Worm   286 NVVGHLGFYDDKIRVDPSKISLASSAMSSLLPIYTYLFMSGLTVSYT--FLKGKPSLDVLKQPFT 348

  Fly   321 --SFFFIGGFLVSLNALGTMEKNNGKINVPRMYIRRFIRIFPILAMSILVYTQLTGVLG---DGP 380
              .|||                            .|:||    |..:::|:.......|   .||
Worm   349 WLIFFF----------------------------HRWIR----LTSALMVFIGFFDAYGKYIQGP 381

  Fly   381 L-FKGGYSKKAS---CAKTWYMTLLFVVNF--ANDMCLDHTWYLAVDMQLFLISPILLFALYKWG 439
            . ...|||....   |  |::|.::.:.||  .::||....|:||||.|..:.:|..|.|.:
Worm   382 YDALTGYSMVTQTDLC--TYWMDIIHISNFVAVDEMCYLPAWHLAVDFQFTIFAPFFLLAFH--- 441

  Fly   440 KKAAAAIGVLIVLLSGCLFATMMVNHYSIKSLDFSLQKKTYFYTHTH---------------AAP 489
              .:..:|.::.:::..:.:.:.|..:    |..::....:...|.|               .||
Worm   442 --YSTVLGTILAIIASLIGSGLTVFFF----LQNTILNSAFTGDHVHDDKLVEIILSKPWNQMAP 500

  Fly   490 WLIGFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAM-LFTSIFALYPKLESGKPWLMTTLEVSSY 553
            :::|.:.|..:..:.|.|..::.:|....||:...: |...||..:.         .:.||.:..
Worm   501 YMMGMIAGCILGKHSGSKRIIHPVASSIIWIIITVLGLVALIFGHFG---------TSQLEKALT 556

  Fly   554 YTLTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQPISKLSYSIYIWHS----FIQEINKRIV 614
            ...||..|.:.:.|::.:......|....:|..|.|:|..|||:..:|.|.    |:..|.:...
Worm   557 NVSTRAVWSICLMWIIISTELKSAGPIGHYLEHPFWRPFGKLSFCAFIVHHMLLYFLFNIQEEAP 621

  Fly   615 RTNTYFSNYQVMLNFWSTMGFTVLFSY----LLYLLIEAPIGGLDRLL--------RPKKKAPAE 667
            :..:::..|     |..|:.. |::||    .|.:::|.||..:|||:        :.:||...|
Worm   622 KYTSFWHEY-----FHYTIPI-VIYSYFLAFFLSVVVEIPILRIDRLIIDQFVPVSKIEKKTDVE 680

  Fly   668 N----KPMTNSDRVGEGHGHDVDLSNQRE 692
            .    |..:|.....:|....:..|.:.:
Worm   681 EDDSFKDTSNRSDNTDGSSKKIKKSPENQ 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	28/122 (23%)
		Acyl_transf_3	266..645	CDD:280013	92/441 (21%)
		OafA	300..666	CDD:224748	89/415 (21%)
oac-50	NP_001309487.1	NRF	86..195	CDD:214781	32/138 (23%)
oac-50	NP_001309487.1	Acyl_transf_3	268..646	CDD:376607	91/437 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.730