DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33337 and oac-55

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_001317839.1	Gene:	oac-55 / 178792	WormBaseID:	WBGene00021479	Length:	742	Species:	Caenorhabditis elegans

Alignment Length:	764	Identity:	182/764 - (23%)
Similarity:	316/764 - (41%)	Gaps:	147/764 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LSFILLSGL--------------VLIGAIQSEDRSVLEEYQRLRK---LKPLGIEF-ADY----- 46
            |.||:.:.|              .|:|.:.:....|:|:.::.:.   :..|||.. |:|
Worm    10 LVFIIFANLQCSSGIEFDPHKAMELLGELIAHPIEVMEQLEKYKTSDLIAALGIHSNANYSISQE 74

  Fly    47 ------FQNVTLNDLSLFDSRLPTQADLLCLNDLTKLVSALQGGQYWAFKMIDAWGGIPSGIFTG 105
                  |....:.|.:.:.....|.|....:.|        |..:.:...|:||.|.:.|||..|
Worm    75 CHEELSFLGYGVIDAARYARHHSTAAVPASMTD--------QERKDYLIPMMDAAGKLGSGIVRG 131

  Fly   106 NVYDLGNFDECINIKKDS------IRGKYCFLDVSPAKIL-------GVESSLAGILKIKTATCF 157
            ::...|.|.||.:|:..|      ::|.|     ..::||       ...:|...:.:|....|.
Worm   132 HILSTGAFSECKSIQMFSSSLNRTVQGDY-----YSSRILFDMKMRPNSFNSSCNLPQIGVDLCL 191

  Fly   158 PASCSATHMNKFVDTILKRILNVSIPSTAMSISDDSCQTAE-SEPWSGLTILTIVILSLMGVIVA 221
            |.||    .|:.:....:..|.   ||.|:|   ..|.... ::....:::.|.::|.::.:||.
Worm   192 PWSC----RNEDLTGYFREALG---PSKALS---PVCSVRNVNQRVPVISLGTWIVLLILSLIVG 246

  Fly   222 IATLYDYFLVKSQDQLHTAV--------KLFSA---RANSCALFRIVVNQSNPNVIECLHGIRCM 275
            :..|..:..:..:.||:...        |||||   ..|...:|. ..|......:..|:.||.:
Worm   247 LCILSGFSDIFQKFQLNDKTRKEEGFGWKLFSAFSFHRNLKEIFN-TKNCHKEGQVTSLNCIRVI 310

  Fly   276 SLFWVVWIHQYDNVFSAPNINRFRFLSWLQTPFT-MFFLEGNFSVDSFFFIGGFLVSLNALGTME 339
            |.|||::.|..:..|.... |......:.:..:| .......||||:||||..||:|......:|
Worm   311 STFWVIFGHCSEITFMVIT-NPIDLYDFTKDTYTGTLISNAYFSVDTFFFISAFLLSFLWFKQLE 374

  Fly   340 KNNGKINVP----RMYIRRFIRIFPILAMSILVYT-QLTGVLGDGPLFKGGYSKKASCAKTWYMT 399
            |....:..|    ..|:.|..|:.|:..::||.:| ..|..:.|.|.|........:|..::::.
Worm   375 KQWNALLSPGGWLMFYVHRIARLSPVYYVTILFFTFVFTRSMVDMPAFMTPAVVDDTCQNSYWVN 439

  Fly   400 LLFVVNFA--NDMCLDHTWYLAVDMQLFLISPILLFALYKWGKKAAAAIGVLI---VLLSGCLFA 459
            ||::.|..  .|:|...:||||.|:|::::||::|.:....|    |.:|:||   ..|:...|.
Worm   440 LLYIQNIVGPKDICYFISWYLATDLQIYIMSPLILLSFGLGG----AVVGLLISTAAFLASTAFN 500

  Fly   460 T--MMVNHYSIKSLDFSLQKKTYFYTHTHAAPW------------LIGFLYGYFVFLNKGRKFKM 510
            .  |:..|:.....::..:...|..:....|.|            ::|.:.||  |:.:..|..:
Worm   501 AYQMIFWHFPPSDYNYGPKDPLYDPSKRRYAAWNYHNPLIRCQIYIMGMVLGY--FMRRIPKINI 563

  Fly   511 N-WI--AVWSGWILCL---AMLFTSIFALYPKLESGKPWLMTTLEVSSYYTLTRVGWPMAVGWVV 569
            | |:  .:|     ||   :|:|  :..:.....||..|  :.|:.:.|...:||.|.:|:.|:|
Worm   564 NPWVDRIMW-----CLSLGSMIF--VIVIMEDYTSGHLW--SPLQTALYSCFSRVVWGLALSWIV 619

  Fly   570 FACMQGYGGMANTFLSSPLWQPISKLSYSIYIWHSFIQEINKRIVRTNTYFSN--YQVML----- 627
            .:... ..|:.|.|:|.|:|.|:::||:..|:.|..:.........:..|||.  |.|::
Worm   620 ISTYY-RKGLINKFMSLPVWTPLARLSFCAYLVHLMVAAYFFGRNHSELYFSTLPYFVLVIAIPV 683

  Fly   628 --------NFWSTMGFTVLFSYLLYLLIEAPIGGLDRLLRPK-KKAPAE 667
                    .||||| |.:.|:.:..||    :||..|...|. .|.|.:
Worm   684 ISCSFLVAIFWSTM-FELPFAKVEALL----LGGGSRSSAPDIPKTPID 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	31/123 (25%)
		Acyl_transf_3	266..645	CDD:280013	109/424 (26%)
		OafA	300..666	CDD:224748	106/412 (26%)
oac-55	NP_001317839.1	NRF	111..220	CDD:214781	31/123 (25%)
oac-55	NP_001317839.1	OafA	299..690	CDD:224748	102/407 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.680