DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33337 and oac-31

DIOPT Version :9

Sequence 1:	NP_996269.2	Gene:	CG33337 / 2768678	FlyBaseID:	FBgn0053337	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_503441.2	Gene:	oac-31 / 178643	WormBaseID:	WBGene00018707	Length:	705	Species:	Caenorhabditis elegans

Alignment Length:	718	Identity:	197/718 - (27%)
Similarity:	326/718 - (45%)	Gaps:	115/718 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKILSFILLSGLVL-----IGAIQSEDRSVLEEYQRLRKLKPLGIEFADYFQNVT---LNDLSL 57
            |.::| |::|| |.|     |..:.|..:.:.:.       |||. :.::...|.|   |..|.:
Worm     1 MTRLL-FLVLS-LFLPFSHCISTMNSNWKDIFDP-------KPLH-DLSEKCLNDTDTWLKSLEI 55

  Fly    58 FDSRLPTQADLLCLNDLTKLVSALQGGQYWAFKMIDAWGGIPS-GIF-TGNVYDLGNFDECINIK 120
            |.:   ...:.|.||:.|...|.:.....:|.|.:||:|..|: |:. ...:|| |::.||..|.
Worm    56 FST---VSVECLTLNNCTTQESKILDENLYAVKQLDAFGEFPTPGLLELRTLYD-GSYQECDRID 116

  Fly   121 KDSIRGKYCFLDVSPAKILGVES-SLAGILKIKTATCFPASCSATHMNKFVDTILKRILNV---- 180
            .:..:..||:|.::..|.:...: |:...:.::.|.|.|.|||...|           :|:
Worm   117 GERYKTNYCYLILNFGKNISCSAPSVYSNVTLRMAVCLPDSCSHQDM-----------INIFNQL 170

  Fly   181 -SIPSTAMSISDDSC--QTAESE-PWSGLTI-LTIVILSLMGVIVAIATLYDYFL--------VK 232
             ..|.||   .|..|  .|.|.: |:.|.|: |||||     .:...|||.||..        :|
Worm   171 SPYPFTA---CDAYCVKNTVEKDVPFWGFTVFLTIVI-----AVAIFATLLDYVQDAVLGLSNLK 227

  Fly   233 SQDQLHTAVKLFSARANSCALFRIVVNQSNPNVIECLHGIRCMSLFWVVWIHQYDNVFSAPN--- 294
            .::.....:..||...|  |...:.|.:..|..|:.|..||.:|:|||:..|.:..:..|..
Worm   228 EKNIFIKIILTFSLWTN--AELILSVKEHKPGFIKSLDCIRGLSIFWVITGHSFIYMTQADTMKP 290

  Fly   295 INRFRFLSWLQTPFTMFFLEGNFSVDSFFFIGGFLVSLNALGTMEKNNGKINVPRM-----YIRR 354
            :..|:...|     ....:....||||||.:.|.:|:.  |....|.|.|:....:     |:.|
Worm   291 VMEFQNQFW-----NHLIINAPVSVDSFFALSGIVVAY--LFFKMKPNIKMAASPVTWILFYVHR 348

  Fly   355 FIRIFPILAMSILVYTQLTGVLGDGPLFKGGYS-----KKASCAKTWYMTLLFVVNFAN------ 408
            ::|:.|.:.:.|..:|.....: .|| |...:|     :..:|...|:..||::.||.|
Worm   349 YLRLTPTVMIFIGFFTVYFPYV-QGP-FAASFSNVQFPQVEACKDYWWHNLLYINNFDNSQHRER 411

  Fly   409 DMCLDHTWYLAVDMQLFLISPILLFALYKWGKKAAAAIGVLIVLLSGC---LFAT-MMVNHYSIK 469
            :.|...|||||||.||::::||:|.||:     .:.|:|..|: ::||   :.|| ::.:.|.:.
Worm   412 NTCYAITWYLAVDTQLYILAPIVLIALF-----FSFAVGTAII-VAGCVGSIIATYILFDLYDVP 470

  Fly   470 SLDFSLQKKTYFYTHTHAAPW------LIGFLYGYFVFLNKGRKFKMNWIAVWSGWILCLAMLFT 528
            :.........||:...::.||      |:|.|.||.:.....|:.::||......||:...:...
Worm   471 ADPLGNGDHRYFFGIGYSKPWIRCPPYLVGLLTGYLLATYGTRRIRLNWAVSIGVWIVAFVVAGF 535

  Fly   529 SIFALYPKLESGKPWLMTTLEVSSYYTLTRVGWPMAVGWVVFACMQGYGGMANTFLSSPLWQPIS 593
            .||:.| ..:.|:.|  :|...::::...|:||.:.|.|||.|...|:||..:||:|.|:|||..
Worm   536 CIFSTY-DYDKGEQW--STFSRATFFNFHRLGWGVFVCWVVGANHMGWGGPIDTFMSHPIWQPFG 597

  Fly   594 KLSYSIYIWHSFIQEINKRIVRTNTYFSNYQVMLNFWSTMGFTVL---FSYLLYLLIEAPIGGLD 655
            :|||..||.|..:......:.....|.|.:.|.|  :.::..|||   |::....|.|.||..|:
Worm   598 RLSYCAYIVHWMVLYFYLNVGGALHYTSAWHVFL--YISIPATVLSFVFAFFWSCLFEMPILKLE 660

  Fly   656 RLL 658
            ::|
Worm   661 KML 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33337	NP_996269.2	NRF	85..196	CDD:214781	31/120 (26%)
		Acyl_transf_3	266..645	CDD:280013	116/410 (28%)
		OafA	300..666	CDD:224748	111/388 (29%)
oac-31	NP_503441.2	NRF	80..184	CDD:214781	31/118 (26%)
oac-31	NP_503441.2	OafA	253..659	CDD:224748	121/425 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I2120
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14368
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.680