| Sequence 1: | NP_996267.1 | Gene: | p53 / 2768677 | FlyBaseID: | FBgn0039044 | Length: | 495 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001120731.1 | Gene: | Trp63 / 22061 | MGIID: | 1330810 | Length: | 680 | Species: | Mus musculus |
| Alignment Length: | 514 | Identity: | 106/514 - (20%) |
|---|---|---|---|
| Similarity: | 188/514 - (36%) | Gaps: | 112/514 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 ASFSLTFNQNTSIVSRSNSRTIFEAFKEFLDFWD-IGNEVSAESAVRV------SSNGAFN-LPQ 63
Fly 64 SFGNESNEYAHLATPVDPAYGGNNTNNMM--QFTNNLEILANNNSD-GNNKINACNKFVCHKGT- 124
Fly 125 DSEDDSTEVDIKEDIPKTVEVSGSELTTEPMAFLQGLNSGNLMQFSQQSVLREMMLQDIQIQANT 189
Fly 190 LPKLENHNIGGYCFSMVLDEPPKSLWMYSIPLNKLYIRMNKAFNVDVQFKSKMPIQPLNLRVFLC 254
Fly 255 F--SNDVSAPVVRCQNHLSVEPLTANNAKMRESLLRSENPNSVYCGNAQGKGISE----RFSVVV 313
Fly 314 PLNMSRSVTRSGLTRQTLAFKFVCQNSCIG---RKETSLVFCLEKACGDIVGQHVIHVKICTCPK 375
Fly 376 RDRIQDERQLNSKKRKSVPEAAEEDEPSKVRRCIAIKTEDTESNDSRDCDDSAAEWNVSRTPDGD 440
Fly 441 YRLAITCPNKEW------LLQSIEGM--IKEAAAEVLRNPNQENLRRHANKLLSLKKRA 491 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| p53 | NP_996267.1 | P53 | 203..383 | CDD:176262 | 47/188 (25%) |
| P53_C | 429..495 | CDD:288471 | 14/71 (20%) | ||
| Trp63 | NP_001120731.1 | Transcription activation. /evidence=ECO:0000250 | 1..107 | 17/79 (22%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 123..171 | 9/47 (19%) | |||
| P53 | 163..358 | CDD:307150 | 55/264 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 351..393 | 10/56 (18%) | |||
| Interaction with HIPK2. /evidence=ECO:0000250 | 352..388 | 9/40 (23%) | |||
| P53_tetramer | 392..431 | CDD:311579 | 9/49 (18%) | ||
| Oligomerization. /evidence=ECO:0000250 | 394..443 | 12/49 (24%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 436..472 | 4/22 (18%) | |||
| Forkhead_N | 452..535 | CDD:312062 | 1/6 (17%) | ||
| SAM_tumor-p63 | 543..607 | CDD:188971 | |||
| Transactivation inhibition. /evidence=ECO:0000250 | 610..680 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167836963 | |
| Domainoid | 1 | 1.000 | 65 | 1.000 | Domainoid score | I9999 |
| eggNOG | 1 | 0.900 | - | - | E1_2C1DX | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0002925 | |
| OrthoInspector | 1 | 1.000 | - | - | otm43341 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR11447 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R5172 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.830 | |||||