Protein Alignment Fancd2 and AT4G14970

DIOPT Version :10

• Sequence 1: NP_996246.1
• Gene: Fancd2 / 2768674
• FlyBaseID: FBgn0038827
• Length: 1478
• Species: Drosophila melanogaster
• Sequence 2: NP_001319941.1
• Gene: AT4G14970 / 827156
• AraportID: AT4G14970
• Length: 1484
• Species: Arabidopsis thaliana
• Alignment Length: 1667
• Identity: 340/1667 - (20%)
• Similarity: 614/1667 - (36%)
• Gaps: 513/1667 - (30%)

  Fly    31 TTNISVESSSGGSEENIPA--------------SQEHTQRFLSQHSVILAATLGRTQSSSRNIAT 81
            |..:|..|::.|..:|:.|              |..:.:|.||..|     |..|.:|..||:
plant    72 TGRLSSFSANSGERDNVGALCSVFVAGFSLYIQSPSNLRRMLSSSS-----TTKRDESLVRNL-- 129

  Fly    82 LSRQPNNFFELVLVRAGVQLDQGDSLILACDHVPIVSKLREIFTSASSYTDKMETFKTGLNAAMA 146
                        |:.:.:|||..:.|:         .||.|.|
plant   130 ------------LLVSPIQLDIQEMLL---------EKLPEYF---------------------- 151

  Fly   147 PGSKLVQKLLTGCTVDAAGEEQIYQSQNSMFMN-FLMIDFMRDACVEVLLNKIEEVAKSDRVIMG 210
                   .::|||::    ||.:.:    :.:| |..:||:.:.  .|..:|:.:|
plant   152 -------DVVTGCSL----EEDVAR----LIINHFRWLDFIVNP--HVFTDKLMQV--------- 190

  Fly   211 KAAIPLPLLPLMLTQLRYLTASHKVEIYSRI-EVIFNRATESAKLDIIANAELILDASMHDEFVE 274
                 |.:.||.|          |.||...: |:|.:.           |.:.::| |:.....|
plant   191 -----LSICPLHL----------KKEIIGSLPEIIGDH-----------NCQAVVD-SLEKMLQE 228

  Fly   275 LLNINYSSTEDLFHMTTVQTLGNLSLSDRTQAK-LRVRILDFATSGQCSDAI----LPHLIRLLL 334
                     :....:..:.:..||:|.|:.|.: :.|.|       .|...|    :|:|:|.||
plant   229 ---------DSAVVVAVLDSFSNLNLDDQLQEQAITVAI-------SCIRTIDGEHMPYLLRFLL 277

  Fly   335 NVLKIDTDDSVRDLIGSLRGIFNWRHTNETEKISASEDSKKSQLELF---GFLELGLIRSKKFYQ 396
            ...   |..:||.:|..:|....:...::.   .||::..|.::..:   |.:...|..|.:|..
plant   278 LAA---TPVNVRRIISQIREQLKFTGMSQP---CASQNKLKGKVPAYNAEGSILHALRSSLRFKN 336

  Fly   397 -ACQR-----SSASVPAAEFTSFDMILLLLLIHVNEDN-SLYIENILRRRIKLEHITVSILEEIR 454
             .||.     :|...| .:|...| :.||:|:::|.|. ...||.|.::::..|.|..::|::..
plant   337 ILCQEIIKELNSLEKP-RDFKVID-VWLLILMYMNGDPVRKSIEKIFKKKVVDECIQEALLDQCI 399

  Fly   455 QHYRHILEQHITTLMNILHDFMREKNRIVSDFAKSSYSILFKIF--NSIQKNILKKLLELTCDKS 517
            ...:..::.:..:.:::....:..|.....:.....||.||:.|  |..::.||..|:......:
plant   400 GGNKEFVKDNFASFVSLAEHLLSSKEEKAREIGSHIYSRLFEEFTDNYSRQEILGALVTHVGSDN 464

  Fly   518 SPHLTTMALELLRELQRKSAKDVQNCATLLIPMLDRISDLSLTQTRVAMDLLCHVAFP-----DP 577
            ...:::: ||::..|.:|.|:.:...::.:..:||.:...::.......::...:|..     |.
plant   465 KFEVSSV-LEMMTALVKKYAQQLLPFSSHINGILDYLEGFTIDNLHKVYEVFSLLALSARASGDS 528

  Fly   578 NLSPCLQLQEQVDMVVKKQLINSIDNIKKQGIIGCVQLIDAMARIANNGVDRDEFIASVENVDSL 642
            ..|   .:..::.|:|:||:.:.....||.|::|.:::                 ::|:.:..|:
plant   529 FRS---SISNELMMIVRKQVSHPDLKYKKMGLVGSLRI-----------------VSSLGDAKSV 573

  Fly   643 PDGRGKMAANL-----IIRTEA-SIGNSTESLALFFEELATVFNQRNEGTSGCELDNQFIAWACD 701
            ||......::.     :::|.. |...|..:|.:|::|.||:.:.:       .|..:.:.|...
plant   574 PDFSSSQVSDCGEILELLKTSVESCRQSNLALIMFYDEFATILSHK-------LLQPEIMEWIGK 631

  Fly   702 LVTFRFQASFVTENVPETLKGIKLEYQLNINELD-DTDANTESDVLNIGINISKLVLSPKVKACD 765
            .:. .|::.|:.:     |:..|:..:.:.:.|: |...|.:..:..|.:||..|..|.....|
plant   632 HLG-EFESLFLAD-----LENEKMAEKGSYSGLEGDLWMNLDGSISPICLNILALASSSSESCC- 689

  Fly   766 SIYVLAPLFNYVRVLYKHRHQDSLESINALLGCAIVLPS--FFEDDNYVSVFENFEAEQQKDILS 828
             :.:|...|..:..:.:..:..||..::|||||.:.|||  :|....:.|:     |::||:|||
plant   690 -LQILPSNFLLLSTVERLTNDGSLAGVDALLGCPLHLPSSKYFAAAGWQSL-----AKKQKEILS 748

  Fly   829 I-YFHTVNWMRVSISAFASQRD-----------PPTRRRVLSRLGELIRIEQRMKPLLARAPVDF 881
            : .::..||:|..::||:||.|           .....::|.||..|:.:|..:..|:..:|...
plant   749 LSLYYAANWIRELLNAFSSQIDEKIGCISQATVKDVTTKLLKRLRNLVFLESLLSNLITLSPQSL 813

  Fly   882 VAP---PY--------------------------QFLTNVKLS-----NQNQKRPGPKPAAK--- 909
              |   ||                          ....|:|.|     |:..::|....|.|
plant   814 --PELHPYSESHVEHPRKKNEKRKLDDDASQRKVSMKNNLKKSKHSDVNEKLRQPTIMDAFKKAG 876

  Fly   910 ---------LNATLPEPDLTGNQPS-IADFTIKVGQCKTVKTKTDFEQMYGPRERYRPMEVEIIM 964
                     |..|...|.:.|:..: ..|......:...||.......:...|.::||:..:.:.
plant   877 AVMSHSQTQLRGTPSLPSMDGSTAAGSMDENCSDNESLIVKIPQVSSALEAQRFKFRPLLPQCLS 941

  Fly   965 LLVEQKFVLNHQLEEEQMG--EFLGLLEL-RFLLEDVVQKLEAAV-------------------- 1006
            :|...|.:      .:.||  |:...|.| .:||.|:..||:..|
plant   942 ILNFPKVL------SQDMGSPEYRAELPLYLYLLHDLHTKLDCLVPPGKQHPFKRGSAPGYFGRF 1000

  Fly  1007 ---------------LRHH-----------DSYDADSFRPHLA---KPE------------DFIC 1030
                           ||.|           |.....::|...|   .|.            ..:|
plant  1001 KLVELLNQIKRLFPSLRIHLNIAISLLIRGDETSQTTWRDEFALSGNPNTSSIVVSESLVYTMVC 1065

  Fly  1031 -DLLPCLHEV---------NNHLITLGEAIDNQLTEV-----------------SHVYSNLDLFK 1068
             ::|.|..::         .:.|:.|.||.  |.||:                 .::|..:..|.
plant  1066 KEVLYCFSKILTLPEFETDKSLLLNLLEAF--QPTEIPVANFPDFQPFPSPGTKEYLYIGVSYFF 1128

  Fly  1069 DQ-------FCYIKSCFGL-CVRLFALYFAWSEWSDKSQEQLLHKSLLKLQPKTQWKRLEKQSVP 1125
            :.       ||.....|.. |...|.|.|               :.||.||       |...||.
plant  1129 EDILNKGNYFCSFTDDFPYPCSFSFDLAF---------------ECLLTLQ-------LVVTSVQ 1171

  Fly  1126 QLANLTFQYFLKYEKSVLNLSTAVHLHRLLCNL-LKLGSLQSDASQPRFQQAEDLRILCGTLLRR 1189
                   :|..|..:.........|.|.|:.|| .|||:           .||       .|||.
plant  1172 -------KYLGKVSEEANRKRNPGHFHGLVPNLHAKLGT-----------SAE-------KLLRH 1211

  Fly  1190 KWFHYSGTLDKGGQCNI-----------YLDELVKGFLK--KSNAKSQTELLTELVKQCSIL--N 1239
            ||...| |.:||.:..:           :..|:|:..|:  ...:.|.::||.||.  |:||  .
plant  1212 KWVDES-TDNKGLKNKVCPFVSNLRIVQFTGEMVQTILRIYLEASGSTSDLLDELA--CTILPQA 1273

  Fly  1240 TKDKALTSFPNFKKANFPLL----FRGLCEVLIHSLSGQVSVDSRGDKLKLWESAVDLLNGLLSI 1300
            :..|:.....:.:...||.|    |||..:.|:                   |..:.:||.|:..
plant  1274 SLSKSTGEDDDARDHEFPTLCAATFRGWYKTLL-------------------EENLAILNKLVKT 1319

  Fly  1301 V----QQVEQPRNFGLFLKHSLLFLKLLLQHGMSALESIVR--EDPERLT----------RFLHE 1349
            |    :|..||:.....||:        :|..::.:.|:|.  ...|::|          :::..
plant  1320 VSSEKRQNCQPKTTEAHLKN--------IQKTVNVVVSLVNLCRSHEKVTIHGMAIKYGGKYVDS 1376

  Fly  1350 LQKVTRFL------HQLCCHSKSIKNTAIISYIPSLRETIETLVFRVKALLAANNCHSAFHMGNM 1408
            ..||..||      |:.......:|.|||.|.||:.:.::|..:|.|||||...:..|.|.||::
plant  1377 FLKVFDFLEAHFQDHKELVIQLGMKQTAITSKIPATKRSLERFLFHVKALLHRTSGGSNFWMGSL 1441

  Fly  1409 INRDLHGDSIITPRSSFAGEENSDDELPADDTSVDETVLGDD 1450
            .::||.|..:    ||.|..:|..||       |:||:.|::
plant  1442 KHKDLRGQIV----SSQAYIDNEADE-------VEETMSGEE 1472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fancd2	NP_996246.1	FANC	132..1422	CDD:473054	305/1522 (20%)
AT4G14970	NP_001319941.1	FANC	95..1455	CDD:473054	326/1618 (20%)