Protein Alignment Pxd and Lpo

DIOPT Version :10

• Sequence 1: NP_996223.1
• Gene: Pxd / 2768671
• FlyBaseID: FBgn0004577
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_536345.2
• Gene: Lpo / 76113
• MGIID: 1923363
• Length: 710
• Species: Mus musculus
• Alignment Length: 610
• Identity: 208/610 - (34%)
• Similarity: 304/610 - (49%)
• Gaps: 52/610 - (8%)

  Fly    95 APPAVCE-KTAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGIS-----APTRSVTGDELPS 153
            ||...|. .:.|||:.|.||:.:.|.||.||....|.|..:|.||:|     .|.:...|..||.
Mouse   125 APTMTCNISSPYRTITGYCNNRKNPALGSANRALARWLPAEYEDGLSLPYGWTPGKMRNGFPLPQ 189

  Fly   154 ARLVS--LVAF-GEQDVPDPEFTLHNMQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGLDT 215
            .|.||  :.|: .|:||.|.:.::..||||||:.|||.............|:...|:..:.|
Mouse   190 PREVSNQIAAYLNEEDVLDQKRSMLFMQWGQIVDHDMDFAPETEMGSDTYTKAQCDEHCIQG--- 251

  Fly   216 AHKTCFAIIVPPHDPAYSQVGTECLNFVRTLTDRDSNC---QYQGGPAEQLTVVTSYLDLSLVYG 277
              ..||.|:.||.||.....| :|:.|.|.    ...|   .|:....||:..:||:||.||||.
Mouse   252 --DNCFPIMFPPGDPKLKTQG-KCMPFFRA----GFVCPTPPYKSLAREQINALTSFLDASLVYS 309

  Fly   278 NSIQQNSDIREFQG--GRMIVEER---NGAKWLPLSRNVTGDCDAVDASE--VCYRSGDVRVNQN 335
            ......:.:|....  |.|.|.|.   ||..:.|..:.....|:.::|:.  .|:.:||.|.::.
Mouse   310 PEPSLANRLRNLSSPLGLMAVNEEVSDNGRPFPPFVKMKPSPCEVINATAGVPCFLAGDSRASEQ 374

  Fly   336 PGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFLGGENMLK 400
            ..||...|:.:|||||:|..||.||||:|..||:||||||..|..|..::.::|||.||.| |.|
Mouse   375 ILLATSHTLFIREHNRLATELSRLNPHWDRETLYQEARKIMGAFIQITTFRDYLPILLGDE-MQK 438

  Fly   401 NRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQIEGRLDLLSELRQVLGS---LTL-SD 461
                :..|...|    :.::||.:.|.. |.|.|:.|.:|...:..|.|..|..||   |.| :.
Mouse   439 ----WIPPYQGY----NESVDPRISNVF-TFALRFGHLEIPSTVYRLDENYQPWGSESELPLHTV 494

  Fly   462 WFNRPGIIEVGDNFDSLTRGHATQPEELTDIN--FDRQIKHFLFRRNMPF-GSDLRSLDIQRNRD 523
            :||...:::.| ..|.|.||...:..:|...|  ...::::.||:.|... |.||.|::|||:||
Mouse   495 FFNTWRLVKDG-GIDPLVRGLLAKNAKLMHQNKMMTGELRNKLFQPNHTIHGFDLASINIQRSRD 558

  Fly   524 HGLASYNDMREFCGLRRAHSWEGYGDLISPPIL-EKLKSLYPSHEDVDLTVGASLEAHVAGALAG 587
            ||...||..|.||||.:..:.|....::...:| :||..||.:..::|:.:||..|..|.....|
Mouse   559 HGQPGYNSWRAFCGLSQPKTLEELSAVMKNEVLAKKLMDLYGTPSNIDIWLGAVAEPLVHRGRVG 623

  Fly   588 PTFLCILTEQFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMARLLCDNGNHISSMQPEAFRT 652
            |...|:|.:||.|.|.||||::||...   ||..|.|.|:|.|.:||:||| ..|..:....|:.
Mouse   624 PLLTCLLGQQFQRIRDGDRFWWENPGV---FTEKQRESLQKMSFSRLVCDN-TGIDKVPLNPFQA 684

  Fly   653 VSHSNPIIPCSNIPQVDLTKWIDQK 677
            .::.:..:.||:|.::||:.|...|
Mouse   685 NAYPHGFVDCSSIDKLDLSPWASVK 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_996223.1	An_peroxidase	105..650	CDD:460804	197/570 (35%)
Lpo	NP_536345.2	myeloperoxidase_like	281..692	CDD:188656	146/425 (34%)