Protein Alignment Pxd and MPO

DIOPT Version :9

• Sequence 1: NP_001163633.1
• Gene: Pxd / 2768671
• FlyBaseID: FBgn0004577
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_000241.1
• Gene: MPO / 4353
• HGNCID: 7218
• Length: 745
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 202/662 - (30%)
• Similarity: 310/662 - (46%)
• Gaps: 98/662 - (14%)

  Fly    53 PYVIGNSLPTSPAPQNPFSSPASPPVSAYGYSFPTAGRVSCAAPPAVCEKTAYRTLDGSCNHLEQ 117
            |:.:.:.|  :||..|..|..:       |.::...| |:|.      |:..|||:.|.||:...
Human   137 PFNVTDVL--TPAQLNVLSKSS-------GCAYQDVG-VTCP------EQDKYRTITGMCNNRRS 185

  Fly   118 PGLGVANSKYGRLLTPKYADGISAP---TRSVTGDELP--SARLVS--LVAF-GEQDVPDPEFTL 174
            |.||.:|..:.|.|..:|.||.|.|   |..|..:..|  .||.||  :|.| .:|..||.|.:|
Human   186 PTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSL 250

  Fly   175 HNMQWGQIMTHDM------SMQAGGTQSKKHPTRCCTDDGRLIGLDTAHKTCFAIIVPPHDPAYS 233
            ..|||||::.||:      :.:|.........|.|           .....||.:.:||:||...
Human   251 MFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSC-----------VQQPPCFPLKIPPNDPRIK 304

  Fly   234 QVGTECLNFVRT--------LTDRDSNCQYQGGPAEQLTVVTSYLDLSLVYGNSIQQNSDIREF- 289
            . ..:|:.|.|:        :|.|:           |:..:||::|.|:|||:......::|..
Human   305 N-QADCIPFFRSCPACPGSNITIRN-----------QINALTSFVDASMVYGSEEPLARNLRNMS 357

  Fly   290 -QGGRMIVEER---NGAKWLPLSRNVTGDCDAVDASE--VCYRSGDVRVNQNPGLAILQTILLRE 348
             |.|.:.|.:|   ||...||........|...:.|.  .|:.:||.|.::.|.|..:.|:||||
Human   358 NQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLRE 422

  Fly   349 HNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFLGGENMLKNRLIYKAPSGSYI 413
            |||:|..|.:|||.:|...|:||||||..|..|.|:|.::||:.||...|.|....|::
Human   423 HNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRS------ 481

  Fly   414 NDFDPNIDPSVLNEHATAAFRYFHSQIEG---RLD-----LLSELRQVLGSLTLSDWFNRPGIIE 470
              ::.::||.:.|.. |.||||.|:.|:.   |||     :....|..|..:..:.|   ..::|
Human   482 --YNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASW---RVVLE 540

  Fly   471 VGDNFDSLTRGHATQPEEL---TDINFDRQIKHFLFRRNMPFGSDLRSLDIQRNRDHGLASYNDM 532
            .|  .|.:.||....|.:|   ..|..| :|:..||.:.|..|.||.:|::||:|||||..||..
Human   541 GG--IDPILRGLMATPAKLNRQNQIAVD-EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAW 602

  Fly   533 REFCGLRRAHSWEGYGDLI-SPPILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFLCILTE 596
            |.||||.:..:....|.:: :..:..||...|.:..::|:.:|...|........||...||:..
Human   603 RRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGT 667

  Fly   597 QFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMARLLCDNGNHISSMQPEAFRTVSHSNPIIP 661
            ||.:.|.||||::||...   |:..|.:.|.:.|:.|::|||....:..:...|.:.|:....:.
Human   668 QFRKLRDGDRFWWENEGV---FSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVN 729

  Fly   662 CSNIPQVDLTKW 673
            ||.:|.::|..|
Human   730 CSTLPALNLASW 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	184/578 (32%)
		peroxinectin_like	260..638	CDD:188655	130/396 (33%)
MPO	NP_000241.1	myeloperoxidase_like	316..728	CDD:188656	136/440 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	1	1.000	-	-		FOG0000202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750