DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pxd and CG42331

DIOPT Version :9

Sequence 1:	NP_001163633.1	Gene:	Pxd / 2768671	FlyBaseID:	FBgn0004577	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_001189281.1	Gene:	CG42331 / 42948	FlyBaseID:	FBgn0259233	Length:	1615	Species:	Drosophila melanogaster

Alignment Length:	597	Identity:	206/597 - (34%)
Similarity:	304/597 - (50%)	Gaps:	36/597 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 PPAVCEKTAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGISAPTRSVTGDELPSARLVSLV 160
            ||.:.....|||.||:||:..:|..|.|...:.|.|.|:|.||:.....|..|..|.|:|.|||:
  Fly   174 PPCMPASERYRTHDGTCNNKRRPRWGAAQMPFNRFLPPEYGDGVDTVRSSADGSTLSSSRFVSLL 238

  Fly   161 AFGEQDVPDPEFTLHNMQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGLDTAHKTCFAIIV 225
            ..|.::...| .||...||||::.|||:..|...........||       |....|..||.|.|
  Fly   239 VHGAREGEAP-LTLMIAQWGQMLDHDMTSTAQPRSINGSIPSCC-------GGKDFHPACFPIKV 295

  Fly   226 PPHDPAYSQVGTECLNFVRTLTDRDSNCQYQGGPAEQLTVVTSYLDLSLVYGNSIQQNSDIREFQ 290
            |..||..:.:...||.|:|:...:..:|....  .||...||||:|.|.:|.||.:.:.:.|.|:
  Fly   296 PLDDPWLAPLKVRCLEFLRSAPAQRRDCVLSW--REQTNQVTSYIDASPIYSNSAKSSDNARVFR 358

  Fly   291 GGRMIVEERNGAKWLPLSRNVTGDCDAVDASEVCYRSGDVRVNQNPGLAILQTILLREHNRIADA 355
            .|.::....:.|:.:         |.....:..|.||||.|..:.|||..:..:.:.||||||..
  Fly   359 HGLLVYGRGDPAEDV---------CQRGAIATKCIRSGDGRSGEQPGLLAMHHVWVGEHNRIAME 414

  Fly   356 LSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFLGGENMLKNRLIYKAPSGSYINDFDPNI 420
            ||.||||:.|..::||.|:|..|.:|.|::.|:||:.||.| ::|...:...||| |...:...:
  Fly   415 LSELNPHWSDEKVYQETRRIVGAMFQHITFREFLPVILGRE-VVKLFDLELMPSG-YYERYSSKV 477

  Fly   421 DPSVLNEHATAAFRYFHSQIEGRLDLLSELRQVL-GSLTLSDWFNRPGIIEVGDNFDSLTRGHAT 484
            :|:|.|..|.||||:.||.::...........|: .:::|.:.|.|..|...| :...|.||.|:
  Fly   478 NPTVANAFAAAAFRFGHSLVQNSYTRCDRHHNVINNNVSLHEEFQRGDIGSAG-SLHRLLRGLAS 541

  Fly   485 QPEELTDINFDRQIKHFLFRR-NMPFGSDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYG 548
            |.....|.....::.:.||:. ..|||.||.:::|||.||||:|.|:..|..|||....||:.:.
  Fly   542 QRALKRDEFITPELTNHLFQTPGFPFGLDLAAINIQRGRDHGIAPYSAWRVPCGLSPILSWDDFA 606

  Fly   549 DLISPPILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGD 613
            :::.|...:::...|.|..|:||.||...|..|.|.|.||||.||:.:||..:|.||||::|||.
  Fly   607 NVVGPESAKRIGHAYRSVHDIDLFVGGIAERPVVGGLVGPTFACIIAQQFSNSRRGDRFWYENGG 671

  Fly   614 KLTGFTPDQLEELRKASMARLLCDN-GNHISSMQPEAFRTVS-HSNPIIPC--SNIPQVDLTKWI 674
            ..:.|||.||..||:.|:|::||.. |.  .::||..|.... ..|....|  .::..:||:.|:
  Fly   672 FESSFTPAQLHSLRRVSLAQVLCRTVGG--GTLQPHIFIPAEFEDNERQTCGVGSLSPIDLSPWL 734

  Fly   675 DQKLYATVDPSH 686
            :|      ||.|
  Fly   735 EQ------DPFH 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	192/540 (36%)
Pxd	NP_001163633.1	peroxinectin_like	260..638	CDD:188655	139/379 (37%)
CG42331	NP_001189281.1	An_peroxidase	183..699	CDD:281139	191/537 (36%)
CG42331	NP_001189281.1	peroxinectin_like	328..696	CDD:188655	139/379 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920