Protein Alignment Pxd and Epx

DIOPT Version :10

• Sequence 1: NP_996223.1
• Gene: Pxd / 2768671
• FlyBaseID: FBgn0004577
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_001100507.1
• Gene: Epx / 303414
• RGDID: 1311882
• Length: 715
• Species: Rattus norvegicus
• Alignment Length: 710
• Identity: 213/710 - (30%)
• Similarity: 323/710 - (45%)
• Gaps: 120/710 - (16%)

  Fly     1 MIRARDLLLLALLGFISSALGLKVSSGYHIVHNQPQSSFPNYHGFSYLQGSAPYVIGNSLPTSPA 65
            :::|.|.:.:| ||.:...|             |||.|.|                .|.......
  Rat    86 VVQAADYMHVA-LGLLEEKL-------------QPQESRP----------------FNVTDVLTE 120

  Fly    66 PQNPFSSPASPPVSAYGYSFPTAGRVSCAAPPAVCEKTA--YRTLDGSCNHLEQPGLGVANSKYG 128
            ||....|.||                .||....| ||.:  |||:.|.||:..:|.||.:|....
  Rat   121 PQLRLLSQAS----------------GCALQDQV-EKCSNKYRTITGRCNNRRRPWLGASNQALA 168

  Fly   129 RLLTPKYADGIS-----APTRSVTGDELPSARLVS--LVAFGEQDV-PDPEFTLHNMQWGQIMTH 185
            |.|..:|.|..|     .|.:...|..||..|.||  :|.|..:.: .|...:|..|||||.:.|
  Rat   169 RWLPAEYEDHRSLPFGWTPGKRRNGFLLPLVRAVSNQIVRFPSKKLTSDQGRSLMFMQWGQFIDH 233

  Fly   186 DMSMQAGGTQSKKHPTRCCTDDGRLIGLDTAHKT------CFAIIVPPHDPAY-SQVGTECLNFV 243
            |:..      :.:.|.|...:    :|:| ..||      ||.|.:||:||.. ||  .:|:.|.
  Rat   234 DLDF------TPESPARVTFN----MGVD-CEKTCAQLPPCFPIKIPPNDPRIKSQ--RDCIPFF 285

  Fly   244 RTLTDRDSNCQYQGGPAEQLTVVTSYLDLSLVYGNSIQQNSDIREFQG--GRMIVEER---NGAK 303
            |:......|   :.....|:..:||::|.|:|||:.:.....:|....  |.:...::   ||..
  Rat   286 RSAPACPQN---RNKVRNQINSLTSFVDASMVYGSEVSLALRLRNRTNYLGLLATNQQFQDNGRA 347

  Fly   304 WLPLSRNVTGDCDAVD--ASEVCYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDR 366
            .||........|...:  ....|:.:||.|.::.|.||.|.|:.:|||||:|..|..||||:...
  Rat   348 LLPFDNLHEDPCLLTNRLVRIPCFLAGDSRASETPKLAALHTLFVREHNRLATELKRLNPHWSGD 412

  Fly   367 TLFQEARKINIAQYQQISYYEWLPIFLGGENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATA 431
            .|:.|||||..|..|.|:|.::||:.||...|.:....|:.        :..|:||.|.|.. |.
  Rat   413 KLYNEARKIVGAMVQIITYRDFLPLVLGKARMRRTLGPYRG--------YCSNVDPRVANVF-TL 468

  Fly   432 AFRYFHSQIEG---RLDLLSELRQ-------VLGSLTLSDWFNRPGIIEVGDNFDSLTRGHATQP 486
            |||:.|:.::.   |||  |:.|.       :|.|...:.|    .|:..| ..|.:.||....|
  Rat   469 AFRFGHTMLQPFMFRLD--SQYRTSAPNSHVLLSSAFFASW----RIVYEG-GIDPILRGLMATP 526

  Fly   487 EELT--DINFDRQIKHFLFRRNMPFGSDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYGD 549
            .:|.  |.....:::..||::....|.||.:|::||:|||||..||..|.||||.:..:......
  Rat   527 AKLNRQDSMLVDELRDKLFQQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSR 591

  Fly   550 LI-SPPILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGD 613
            :: :..:..|..:||.:.:::|:.|||..|..:.||..||...|:...||.|.|.||||:::
  Rat   592 VLKNRNLARKFLNLYKTPDNIDIWVGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQ--- 653

  Fly   614 KLTGFTPDQLEELRKASMARLLCDNGNHISSMQPEAFRTVSHSNPIIPCSNIPQVDLTKW 673
            |...||..|.:.||:.|::|::||| ..||::..:.||...:....:.||.||:::|:.|
  Rat   654 KWGVFTKRQRKALRRISLSRIVCDN-TGISTVSRDIFRANIYPQGFVSCSRIPKLNLSAW 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_996223.1	An_peroxidase	105..650	CDD:460804	183/579 (32%)
Epx	NP_001100507.1	myeloperoxidase_like	287..699	CDD:188656	134/434 (31%)