DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pxd and Ptgs1

DIOPT Version :9

Sequence 1:	NP_001163633.1	Gene:	Pxd / 2768671	FlyBaseID:	FBgn0004577	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_058739.4	Gene:	Ptgs1 / 24693	RGDID:	3439	Length:	602	Species:	Rattus norvegicus

Alignment Length:	426	Identity:	90/426 - (21%)
Similarity:	157/426 - (36%)	Gaps:	139/426 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   270 LDLSLVYGNSIQQNSDIREFQGGRMIVEERNGAKWLPLSRNVTGDCDAVDASEVCYR-------S 327
            :||..:||:|:::...:|.|:.|::..:..:|..:.|          :|:.:.|..|       .
  Rat   230 VDLGHIYGDSLERQYHLRLFKDGKLKYQVLDGEVYPP----------SVEQASVLMRYPPGVPPE 284

  Fly   328 GDVRVNQN-----PGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYE 387
            ..:.|.|.     |||.:..||.||||||:.|.|...:|.:||..|||..|.|.|.:..:|...|
  Rat   285 KQMAVGQEVFGLLPGLMLFSTIWLREHNRVCDLLKEEHPTWDDEQLFQTTRLILIGETIKIIIEE 349

  Fly   388 WLPIFLGGENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQIEGRLDLLSELRQ 452
            ::....|....||               |||.:              .|.:|.:.|
  Rat   350 YVQHLSGYFLQLK---------------FDPEL--------------LFRAQFQYR--------- 376

  Fly   453 VLGSLTLSDWFNRPGIIEVGDNFDSLTRGHATQPEELTDINFDRQIKHFLFRRNM--PFGSDL-- 513
                       ||     :...|:.|...|...|:.....:.:...:.|||..:|  .:|.:.
  Rat   377 -----------NR-----IALEFNHLYHWHPLMPDSFQVGSQEYSYEQFLFNTSMLVDYGVEALV 425

  Fly   514 --------------RSLD----------IQRNRDHGLASYNDMREFCGLRRAHSWEGY-GDLISP 553
                          |:.|          |:.:|:..|.|:|:.|:..||:...|::.: |:   .
  Rat   426 DAFSRQRAGRIGGGRNFDYHVLHVAEDVIKESREMRLQSFNEYRKRFGLKPYTSFQEFTGE---K 487

  Fly   554 PILEKLKSLYPSHEDVDLTVGASLEAHVAGALAGPTFL--------------CILTEQFYR--TR 602
            .:..:|:.||...:.::...|..||.....:|.|.:.:              .|.:.::::  |.
  Rat   488 EMAAELEELYGDIDALEFYPGLMLEKCQPNSLFGESMIEMGAPFSLKGLLGNPICSPEYWKPSTF 552

  Fly   603 VGDRFFFENGDKLTGFTPDQLEELRKASMARLLCDN 638
            .||          .||     ..:..||:.:|:|.|
  Rat   553 GGD----------VGF-----NIVNTASLKKLVCLN 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	90/426 (21%)
Pxd	NP_001163633.1	peroxinectin_like	260..638	CDD:188655	89/424 (21%)
Ptgs1	NP_058739.4	EGF_CA	35..72	CDD:238011
Ptgs1	NP_058739.4	prostaglandin_endoperoxide_synthase	92..578	CDD:188648	90/426 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810