DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pxd and Nox3

DIOPT Version :9

Sequence 1:	NP_001163633.1	Gene:	Pxd / 2768671	FlyBaseID:	FBgn0004577	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	NP_945196.2	Gene:	Nox3 / 224480	MGIID:	2681162	Length:	568	Species:	Mus musculus

Alignment Length:	173	Identity:	37/173 - (21%)
Similarity:	62/173 - (35%)	Gaps:	48/173 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   502 LFRRNMPFGSDLRSLDIQRNRDH----GLASYNDMREFCGLRRAHSWEGYGDLISPPIL---EKL 559
            :.|...|  ..||..::...|||    ..|:...:.:|.| :...:|:.   .:.|.:|   |::
Mouse   225 IIRGQTP--ESLRLHNVTYCRDHYAEWQAAALCPVPQFSG-KEPSAWKW---ALGPVVLYACERI 283

  Fly   560 KSLYPSHEDVDLT-----VGASLEAHVAGA-----------LAGPTFLCILTEQFYRTRVGDRFF 608
            ...:.||::|.:|     ..|.||.|:...           :..|:...:....|..|......|
Mouse   284 IRFWRSHQEVVITKVVSHPSAVLELHMKKRDFKMAPGQYIFIQCPSVSPLEWHPFTLTSAPQEDF 348

  Fly   609 FE-----NGD---------KLTGFTPDQLEELRKASMARLLCD 637
            |.     :||         ::.|..|.:|     .||.||..|
Mouse   349 FSVHIRASGDWTEALLKAFRVEGQAPSEL-----CSMPRLAVD 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	37/173 (21%)
Pxd	NP_001163633.1	peroxinectin_like	260..638	CDD:188655	37/173 (21%)
Nox3	NP_945196.2	Ferric_reduct	66..217	CDD:280043
Nox3	NP_945196.2	NOX_Duox_like_FAD_NADP	295..568	CDD:99783	20/97 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910