DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pxd and epx

DIOPT Version :9

Sequence 1:	NP_001163633.1	Gene:	Pxd / 2768671	FlyBaseID:	FBgn0004577	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	XP_002933592.2	Gene:	epx / 100496213	XenbaseID:	XB-GENE-6039946	Length:	716	Species:	Xenopus tropicalis

Alignment Length:	624	Identity:	200/624 - (32%)
Similarity:	291/624 - (46%)	Gaps:	97/624 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 PAVCEKTAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGISAP-----TRSVTGDELPSARL 156
            |..|:::.|||:.|.||:.:.|.||.:|:.:.|||...|.||:|.|     ...:.|..||.||.
Frog   138 PRACQESTYRTITGECNNRKNPILGASNTGFTRLLPAVYEDGVSLPRGWTENLPINGFPLPLARA 202

  Fly   157 VS--LVAFGEQDVPDPEFTLHN------MQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGL 213
            ||  :|.|     |:...||..      |||||...||:.:      |.:.|.|....:|  |..
Frog   203 VSNEIVRF-----PNENLTLDQGRALIFMQWGQWTDHDLDL------SPETPARSTFLEG--IDC 254

  Fly   214 DTA---HKTCFAIIVPPHDPAYSQVGTECLNFVRTLTD-----RDSNCQYQGGPA-EQLTVVTSY 269
            ||:   ...||.:.:||:||.           :|..:|     |.|.....|.|. ||:.|:||:
Frog   255 DTSCAKQPPCFPLKIPPNDPR-----------IRNQSDCIPLFRSSPVCTPGSPVREQINVLTSF 308

  Fly   270 LDLSLVYGN------SIQQNSDIREFQGGRMIVEER---NGAKWLPLSRNVTGDCDAVDASE--V 323
            ||.|.|||:      .::.|::    |.|.|.:.::   ||..:||........|...:.|.  .
Frog   309 LDGSQVYGSDWPLAVKLRNNTN----QLGLMAINQKFTDNGLPFLPFETAEEDFCVLTNRSSGIP 369

  Fly   324 CYRSGDVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEW 388
            |:..||.||::.|||....|:.:|.||.||..|..|||.:...||:||||||.....|:|:|.:|
Frog   370 CFLGGDPRVSEQPGLTAFHTLFVRAHNNIATRLRELNPRWSGETLYQEARKIVGGILQKITYKDW 434

  Fly   389 LPIFLGGENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQI--------EGRLD 445
            ||:.||.| |......|::        ::.|:||.|.|.. |..||..|:.|        :|...
Frog   435 LPLLLGSE-MATVLPAYRS--------YNENVDPRVANVF-TVVFRMGHTLIQPFIYRLADGYRP 489

  Fly   446 LLSELRQVLGSLTLSDWFNRPGIIEVGDNFDSLTRGHATQPEELTDIN---FD--RQIKHFLFRR 505
            |..|.|..|.....:.|    .::..| ..|.|.||......:|...|   .|  |:....||:|
Frog   490 LNPEPRVPLHMTFFNSW----RVVREG-GIDPLLRGLMANRAKLNRQNQLVVDELRERLFVLFKR 549

  Fly   506 NMPFGSDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYGDLI-SPPILEKLKSLYPSHEDV 569
               .|.||.::::||.|:|||..||..|.||||....:.:....:: :..:.||...||.:.|::
Frog   550 ---IGLDLTAINMQRGREHGLPGYNAWRRFCGLSAPRNVDELAAVLNNRGLAEKFVKLYGTPENI 611

  Fly   570 DLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMARL 634
            |:.||...|:.|.....|....|::..||.|.|.||||::|   :.|.||..|...:.:.::||:
Frog   612 DIWVGGVAESLVRNGRIGKLLTCLIGNQFRRARDGDRFYYE---QPTVFTNAQRASIERVTLARV 673

  Fly   635 LCDNGNHISSMQPEAFRTVSHSNPIIPCSNIPQVDLTKW 673
            :||| ..|:.:....|....:.....|||.||.:||..|
Frog   674 ICDN-TKITEVPRNVFLGNQYPRDFFPCSRIPTLDLNPW 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	188/584 (32%)
Pxd	NP_001163633.1	peroxinectin_like	260..638	CDD:188655	130/403 (32%)
epx	XP_002933592.2	myeloperoxidase_like	288..697	CDD:188656	137/434 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	1	1.000	-	-		FOG0000202
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010