DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pxd and mpo

DIOPT Version :9

Sequence 1:	NP_001163633.1	Gene:	Pxd / 2768671	FlyBaseID:	FBgn0004577	Length:	690	Species:	Drosophila melanogaster
Sequence 2:	XP_002935236.4	Gene:	mpo / 100490938	XenbaseID:	XB-GENE-482502	Length:	725	Species:	Xenopus tropicalis

Alignment Length:	623	Identity:	205/623 - (32%)
Similarity:	306/623 - (49%)	Gaps:	101/623 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 CEKTAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGISAP-----TRSVTGDELPSARLVS- 158
            |..:.|||..|.||:...|..||:|..|.|||..:|.|..|.|     .|.:.|..||.||.||
Frog   141 CPNSRYRTFTGECNNRRFPNFGVSNRPYTRLLPAQYEDSRSLPRGWTENRRINGFMLPLARAVSN 205

  Fly   159 -LVAFGEQDVPDPEFTLHN------MQWGQIMTHDMSMQAGGTQSKKHPTRCCTDDGRLIGLDTA 216
             ::.|     |:.|.||.|      |||||.:.||:.:      :.:.|.|    ...|.|:|..
Frog   206 QILQF-----PEREQTLDNQRSLMFMQWGQWIDHDVDL------APETPAR----SSFLKGIDCD 255

  Fly   217 HK-----TCFAIIVPPHDPAYSQVGTECLNFVRTLTDRDSNCQYQGGPAEQLTVVTSYLDLSLVY 276
            |.     .||.:.:||:||.. |..::|:...|:     |.....|...||:.|:|||:|.|.||
Frog   256 HSCAKELPCFPLRIPPNDPRI-QNRSDCIPLFRS-----SPACVPGPVLEQINVLTSYVDASQVY 314

  Fly   277 GNSIQQNSDIREF-------QGGRMIVEER---NGAKWLPLSRNVTGDCDAVDASE--VCYRSGD 329
            |::    :|:...       |.|.|.|..|   .|..:||.|......|...:.:.  .|:.:||
Frog   315 GST----NDLARMLRNNTAGQLGLMAVNTRFTDGGLPYLPFSTMKEDFCVLTNETSGLPCFLAGD 375

  Fly   330 VRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFLG 394
            .||::.|||....||.:|||||||..|..:||::....:|||||||..|..|:|:|.::||:.||
Frog   376 ARVSEQPGLTAFHTIFVREHNRIARELRRINPNWTGEIIFQEARKIVGAVEQKINYKDYLPLLLG 440

  Fly   395 GENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQIEGRLDLL-------SELRQ 452
            ..   ..|::   |..:..||   :::|...|.. :..||..|:.|:..:..|       |.|..
Frog   441 SS---MPRVL---PRYTTYND---SVNPGASNVF-SLVFRMGHTMIQPFIFRLVDGYRASSSLPP 495

  Fly   453 VLGSLTLSDWFNRPGIIEVGDNFDSLTRGHA-------TQPE----ELTDINFDRQIKHFLFRRN 506
            |...||   :||...:|..| ..|.|.||..       ||.:    :|||..|:      ||:|
Frog   496 VPLHLT---FFNTWRVILEG-GVDPLLRGLIANKAKLNTQTQILVTQLTDHLFE------LFKR- 549

  Fly   507 MPFGSDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYGDLI-SPPILEKLKSLYPSHEDVD 570
              .|.||.::::||.|||||..||..|..|||.:..:......:: :..:.:||.|||.:.:::|
Frog   550 --LGLDLGAINMQRGRDHGLPGYNAFRRLCGLSQPRNESELAAVLRNNQLAQKLISLYGTPDNID 612

  Fly   571 LTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMARLL 635
            :.:||..|..:.....|....|::.:||.|||.||||::|   :.:.|||.||..:.:||:||::
Frog   613 IWMGAVAEPLITNGRVGELLACLIGDQFRRTRDGDRFYYE---RASVFTPAQLRSIERASLARIV 674

  Fly   636 CDNGNHISSMQPEAFRTVSHSNPIIPCSNIPQVDLTKW 673
            ||| ..|:.:..:.|:..::....:.||:||.:||:.|
Frog   675 CDN-TRITEVPRDVFKANNYPANFVRCSSIPALDLSPW 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	195/586 (33%)
Pxd	NP_001163633.1	peroxinectin_like	260..638	CDD:188655	137/408 (34%)
mpo	XP_002935236.4	An_peroxidase	146..688	CDD:397287	196/593 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	1	1.000	-	-		FOG0000202
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010