DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33331 and TAM41

DIOPT Version :9

Sequence 1:	NP_996213.1	Gene:	CG33331 / 2768668	FlyBaseID:	FBgn0067628	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_011560.3	Gene:	TAM41 / 852937	SGDID:	S000003278	Length:	385	Species:	Saccharomyces cerevisiae

Alignment Length:	336	Identity:	104/336 - (30%)
Similarity:	150/336 - (44%)	Gaps:	95/336 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 YMFAYGSGVKQQEGYGKVGNGNNLRPPPGTVVDLVFCVRDARGFHAENLHRHPDHYSALRHLGPN 83
            ::|.|||||.:|.||.|    ::.:|.    :|::..|.....||:.|:.::|.|||:|::.|..
Yeast   126 FVFGYGSGVFEQAGYSK----SHSKPQ----IDIILGVTYPSHFHSINMRQNPQHYSSLKYFGSE 182

  Fly    84 FVAKYQERLGAGVYCNTLVPLPDV-GITIKYGVVSQEELLEDLLDWRHLYLAGRLHKPVTNLVNP 147
            ||:|:|: :|||||.|   |..:: |..:||||||.|.||:|:..|...||||||.|||..|.|.
Yeast   183 FVSKFQQ-IGAGVYFN---PFANINGHDVKYGVVSMETLLKDIATWNTFYLAGRLQKPVKILKND 243

  Fly   148 S-----DNPPLKAA--------LERNLVSALQVALLLLPEKFTAYGLFHTIAGLSYKGDFR-MIF 198
            .     :...||||        ||:|            ..||..:..:..|..|||.||.| .:.
Yeast   244 LRVQYWNQLNLKAAATLAKHYTLEKN------------NNKFDEFQFYKEITALSYAGDIRYKLG 296

  Fly   199 GENKQKVHNIVSPQINDFFALYQPSLGQLSDYVAVNMKGQEPGSRKPAIIFEQDKSSSATCQHLR 263
            |||..||:|||:.....|...|:|    :...|.:|..            |...|..:     |:
Yeast   297 GENPDKVNNIVTKNFERFQEYYKP----IYKEVVLNDS------------FYLPKGFT-----LK 340

  Fly   264 QLPRELQKRLQRNAACRGDYTQVVNHLSMASQLPEVLQASVNDIVWRSSVTQSIKNIPSAGILKS 328
            ...|.|..|:.                                   :||..|:||.:.:|||.||
Yeast   341 NTQRLLLSRIS-----------------------------------KSSALQTIKGVFTAGITKS 370

  Fly   329 LAYSYRKAQKT 339
            :.|::.|..|:
Yeast   371 IKYAWAKKLKS 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33331	NP_996213.1	Mmp37	5..338	CDD:286252	103/333 (31%)
TAM41	NP_011560.3	Mmp37	113..380	CDD:401180	103/333 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346725
Domainoid	1	1.000	123	1.000	Domainoid score	I1222
eggNOG	1	0.900	-	-		E1_KOG2986
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	152	1.000	Inparanoid score	I1113
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005617
OrthoInspector	1	1.000	-	-		oto100244
orthoMCL	1	0.900	-	-		OOG6_103248
Panther	1	1.100	-	-	LDO	PTHR13619
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1478
SonicParanoid	1	1.000	-	-		X4021
TreeFam	1	0.960	-	-
	13	12.780